A5049057154- Parkinson's Disease Mechanisms and Treatments
- Neurological disorders and treatments
- Advanced Neuroimaging Techniques and Applications
- Neuroscience and Neuropharmacology Research
- Acute Ischemic Stroke Management
- Epilepsy research and treatment
- Multiple Sclerosis Research Studies
- Metabolism and Genetic Disorders
- Mitochondrial Function and Pathology
- Alzheimer's disease research and treatments
- Genetic Neurodegenerative Diseases
- Fungal Infections and Studies
- Systemic Lupus Erythematosus Research
- Neuroinflammation and Neurodegeneration Mechanisms
- Cerebrovascular and Carotid Artery Diseases
- Intracerebral and Subarachnoid Hemorrhage Research
- Muscle Physiology and Disorders
- Adenosine and Purinergic Signaling
- Neurogenetic and Muscular Disorders Research
- Pharmacological Effects and Toxicity Studies
- Adipokines, Inflammation, and Metabolic Diseases
- Head and Neck Anomalies
- T-cell and B-cell Immunology
- Dysphagia Assessment and Management
- Botulinum Toxin and Related Neurological Disorders
Dalian Medical University
2012-2025
Second Affiliated Hospital of Chongqing Medical University
2012-2025
Chongqing Medical University
2012-2025
Ningbo No.6 Hospital
2015-2017
University of Malaya
1987-2012
National Neuroscience Institute
2007
Sungkyunkwan University
2006
Hospital Kuala Lumpur
1989-2002
Mount Elizabeth Hospital
1993
The aims of this study were to examine the clinical and laboratory features Malaysian patients with systemic lupus erythematosus (SLE) identify any difference in disease expression between different genders among three major ethnic groups Malaysia. Retrospective analysis all SLE admitted followed-up at University Hospital Kuala Lumpur from 1974—90 was undertaken. Ethnic Chinese had highest prevalence compared other groups. There a high incidence renal disease, 74% patient significant...
Cerebral ischemia-reperfusion (I/R) is associated with increased levels of reactive oxygen species (ROS) and brain edema, which lead to the deterioration patient prognosis. Resveratrol serves a neuroprotective role in I/R injury, this may be its anti‑oxidative effects. However, resveratrol's mechanism action cerebral injury remains fully understood. In order investigate effect resveratrol I/R‑induced male Sprague‑Dawley rats were randomly assigned four groups: The sham‑operation group, group...
• Thirty consecutive patients from peninsular Malaysia with clinically definite multiple sclerosis were studied; 80% ethnic Chinese, a female-male ratio of 5:1. The average age at onset was 29.7 years, one relapse every 1.9 years. Optic-spinal recurrence the most common clinical pattern disease, accounting for 63.3% (19/ 30) cases. All had spinal cord involvement sometime during course illness. mortality high 36.7% (11/30), an duration symptoms 7.6 There characteristic severe residual visual...
Objective: To identify risk factors for early neurological deterioration (END) in acute lacunar stroke patients and its influence on functional outcome. Methods: Consecutive defined by magnetic resonance imaging (MRI) between January 2018 June 2020 were included the study. END was as any persisting increase National Institutes of Health Stroke Scale (NIHSS) score ⩾ 2 points post admission, favorable outcome a modified Rankin (mRS) 0–2 at discharge. Univariable multivariable logistic...
Thirty four patients with cryptococcal meningitis seen in the University of Malaya medical centre since 1980 were reviewed. Eleven had bilateral papilloedema and visual impairment but eventually survived. Seven intensive aggressive measures, including shunting to reduce intracranial hypertension irrespective ventricular size shown CT scan, showed substantial improvement vision. It is concluded that failure reflects raised pressure this should be treated vigorously.
The aim of the study was to determine spectrum clinical ocular involvement in patients with inactive systemic lupus erythematosus (SLE) who have no symptoms. Patients a diagnosis SLE based on 1982 revised American College Rheumatology criteria and complaints were recruited from clinic. Clinical data regarding their disease activity recorded full ophthalmic examination carried out. 52 mixed ethnicity comprising 75% Chinese, 19% Malays 6% Indian recruited. Of these, 51 (98%) female mean age...
Magnetic resonance imaging (MRI) of the brain is most important paraclinical diagnostic test in multiple sclerosis (MS). The appearance MRI Asians with MS not well defined. We retrospectively surveyed first and spinal cord patients diagnosed to have MS, according Poser's criteria seven regions throughout Asia define changes among MS. There were 101 brain, 86 MRI, 66 whom had both. showed a mean 17 lesions per patient T2 weighted images, mostly asymptomatic. Almost all white matter,...