A5024297014- Healthcare Regulation
- Antifungal resistance and susceptibility
- Public Health in Brazil
- Fungal Infections and Studies
- Healthcare during COVID-19 Pandemic
- Health, Nursing, Elderly Care
- Phytochemistry Medicinal Plant Applications
- Nail Diseases and Treatments
- Infection Control in Healthcare
- Antibiotics Pharmacokinetics and Efficacy
- Analytical Chemistry and Chromatography
- Pneumocystis jirovecii pneumonia detection and treatment
- Youth, Drugs, and Violence
- Antibiotic Use and Resistance
- Drug Solubulity and Delivery Systems
- Phytochemicals and Antioxidant Activities
- Skin Protection and Aging
- Computational Drug Discovery Methods
- Antibiotic Resistance in Bacteria
- Pharmaceutical Practices and Patient Outcomes
- Essential Oils and Antimicrobial Activity
- Sleep and related disorders
- Health Education and Validation
- Bacterial biofilms and quorum sensing
- Transplantation: Methods and Outcomes
Universidade Federal da Bahia
2020-2025
Universidade do Estado da Bahia
2021-2025
Universidade Federal do Rio Grande do Sul
2017-2025
Universidade Salvador
2022-2024
Instituto de Ciências Farmacêuticas
2022
Hospital Ana Nery
2020-2021
Universidade Federal do Rio Grande
2021
Universidade Federal de Juiz de Fora
2021
Universidade Regional Integrada do Alto Uruguai e das Missões
2010-2020
Universidade Federal de Santa Maria
2009-2012
Herbal drugs have been used since ancient times to treat a wide range of diseases. Morinda citrifolia Linn (popularly known as "Noni") has in folk medicine by Polynesians for over 2,000 years. It is reported broad therapeutic effects, including effects against headache, fever, arthritis, gingivitis, respiratory disorders, infections, tuberculosis, and diabetes. The aim this study was investigate the antioxidant, anti-inflammatory, antinociceptive, antibacterial properties aqueous extract...
Assessing the disseminated meningitis caused by Cryptoccocus neoformans in Wistar rats and its impact on antifungal distribution microdialysis (µD). The yeast presence was investigated different tissues histological microbiological assays, biochemical parameters such as urea, glutamate oxaloacetate transaminase (GOT), pyruvate (GPT), creatinine, creatine kinase (CK), albumin level, leukocyte counts, brain vascular permeability (Evans blue test) were evaluated healthy infected groups. Levels...
Tyrosine is an enzyme responsible for melanin production. Its abnormal accumulation in different parts of the body known as hyperpigmentation. Tyrosinase inhibitors have been used one main approaches to treat these kinds cosmetic and medical issues. This review aimed discuss advances patents this class inhibitors, focusing on synthetic ones, by studying recent patent applications (2012-2022). We performed a screening using European Patent Office's Espacenet database, from which 15 inventions...
ABSTRACT To make advances in the treatment of cryptococcal meningitis, it is crucial to know a given drug's free fraction that reaches biophase. In present study, we applied microdialysis (μD) as tool determine levels reached by voriconazole (VRC) brains healthy and Cryptococcus neoformans -infected rats. The infection was induced intravenous (i.v.) administration 1 × 10 5 CFU yeast. dose administered mg/kg (of body weight) VRC, i.v. Plasma microdialysate samples were analyzed liquid...
Pereskia aculeata has been widely investigated due to its anti-inflammatory potential. Among the metabolites found in this species are phytosterols beta-sitosterol (β-SIT) and stigmasterol (STIG). The objective of study was evaluate toxicity activities hexane partition P. (PHEX), as well β-SIT STIG. PHEX prepared were quantified. In terms against L929 fibroblast cells, showed up 200 μg/mL; STIG 25 μg/mL. inhibited 66 % nitric oxide radicals, while 33.73 34.94 %, respectively. an test...
In this study, the distribution and prevalence of extended-spectrum beta-lactamases belonging to TEM, SHV CTX-M families were estimated among samples Escherichia coli Klebsiella spp. at university hospital Santa Maria, Rio Grande do Sul. Over a 14-month period, 90 microorganisms selected as likely ESBL producers. The isolates subjected confirmatory phenotype tests for presence ESBL. Through investigating respective genes using polymerase chain reaction, types present in each microorganism...
INTRODUÇÃO: A candidíase vaginal é uma condição que afeta um grande número de mulheres em idade fértil. Candida albicans a espécie mais frequentemente isolada secreção vaginal, entretanto, outras espécies resistentes às drogas antifúngicas podem ser isoladas amostras clínicas vaginais. MÉTODOS: Foram identificadas as 30 isolados vaginais sp por PCR utilizando o primer universal ITS4 e primers espécie-específicos para C. albicans, glabrata, tropicalis krusei. sensibilidade destes frente à...
Justificativa: Atualmente há um aumento das infecções fúngicas, especialmente em pacientes imunocomprometidos. Dentre os fungos causadores de invasivas destacam-se as leveduras do gênero Candida, considerada marcador progressão HIV. A terapêutica antifúngica e diagnóstico são importantes para o tratamento candidíase oral, devido à resistência atribuída a algumas espécies. Assim, destaca-se importância determinar incidência oral portadores vírus Objetivo: Pesquisar Candida spp HIV positivos,...
Objetivo: Identificar os microrganismos presentes nas mãos dos profissionais de saúde uma unidade terapia intensiva e verificar as causas da baixa adesão à higienização das mãos. Método: Estudo quali-quantitativo, exploratório, do tipo transversal. A coleta dados qualitativos foi por meio entrevista semiestruturada quantitativos análise cultura coletada intensiva. Participaram estudo enfermeiros, técnicos em enfermagem médicos. Utilizou-se a conteúdo para observação crescimento placas...