A5077876683- Epigenetics and DNA Methylation
- Histone Deacetylase Inhibitors Research
- SARS-CoV-2 and COVID-19 Research
- COVID-19 Clinical Research Studies
- Long-Term Effects of COVID-19
- Vehicle License Plate Recognition
- Cancer Cells and Metastasis
- Genomics and Chromatin Dynamics
- Protein Degradation and Inhibitors
- Millimeter-Wave Propagation and Modeling
- Fatty Acid Research and Health
- Income, Poverty, and Inequality
- IoT-based Smart Home Systems
- Nanoplatforms for cancer theranostics
- Network Security and Intrusion Detection
- Advanced Antenna and Metasurface Technologies
- Cancer-related gene regulation
- PARP inhibition in cancer therapy
- Agriculture Sustainability and Environmental Impact
- Advanced Malware Detection Techniques
- Glioma Diagnosis and Treatment
- Essential Oils and Antimicrobial Activity
- Pesticide Residue Analysis and Safety
- Phytochemistry and Biological Activities
- Diet and metabolism studies
National Institute of Technology Meghalaya
2024
Cleveland Clinic Lerner College of Medicine
2021-2023
Cleveland Clinic
2021-2023
Galgotias University
2023
Gordon College
2023
Thapar Institute of Engineering & Technology
2020-2022
Shoolini University
2022
University of Aberdeen
2022
Indian Institute of Science Education and Research, Bhopal
2021
Glioblastomas (GBMs) are heterogeneous, treatment-resistant tumors driven by populations of cancer stem cells (CSCs). However, few molecular mechanisms critical for CSC population maintenance have been exploited therapeutic development. We developed a spatially resolved loss-of-function screen in GBM patient-derived organoids to identify essential epigenetic regulators the SOX2-enriched, therapy-resistant niche and identified WDR5 as indispensable this population. is component WRAD complex,...
Digitally coded programmable metasurface (DCPM) plays a pivotal role in manipulating electromagnetic wave propagation desired direction. To make them or reconfigurable active devices like PIN and varactor diodes are employed to acquire 2 <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">n</sup> number states. This paper analytically methodologically explores the reflection characteristics of different sizes 2-bit DCPM at their central frequency...
In this paper we have presented the design of voice based navigation system for blind using recognition module and GPS implemented on arduino board.This helps person to navigate.The will give destination's name as input module.GPS continously receives latitude longitude current location .GPS compares it with longitude.The pronounced directions which he needs follow reach his destination.
ABSTRACT Collective cell migration (CCM), in which cell–cell integrity remains preserved during movement, plays an important role the progression of cancer. However, studies describing CCM cancer are majorly focused on effects extracellular tissue components moving plasticity. The molecular and cellular mechanisms remain poorly explored. Here, we report that proteolipid protein 2 (PLP2), a colonic epithelium-enriched transmembrane protein, vital invasive human colorectal (CRC) epithelium by...
INTRODUCTION: Mobile devices are integrated into daily activities of people's life. Compared to desktop computers the growth mobile is tremendous in recent years. The opens vast scope for attackers on these devices.OBJECTIVES: This paper presents a deep study different types security risks involved and applications. METHODS: In this we various mechanisms their We also how prevent devices.RESULTS: Various solutions provided through which operators can protect privacy user data keep customers'...
A major issue nowadays is aquatic contamination by heavy metals like Chromium as a result of industrial, agricultural and domestic activities cause threat to the ecosystem. This study's objective was evaluate toxicological effects chromium (VI) in freshwater food fish, Channa punctatus. For experiment, medium-sized fish (10 ± 2 cm, 30 5 g) collected from local habitat acclimatised lab under controlled conditions. There were one control three exposed groups having different sublethal...
Abstract Bistorta macrophylla (D. Don) Sojak. is a medicinal plant of high altitude and so far, not been scientifically explored? Since prehistoric times, B. has used to cure stomach pain, pyretic fever, flu, lungs infections, diarrhea, vomiting. The present research was aimed examine the phytochemicals, antifungal, synergistic potential methanolic extracts macrophylla. Methanolic extract found have phenolic (191.18 ± 29.18 mg g −1 GAE) flavonoid (26.71 3.21 RE) content. also demonstrate...
Abstract Glioblastomas (GBMs) are heterogeneous, treatment-resistant tumors that driven by populations of cancer stem cells (CSCs). Despite their importance for tumor growth, few molecular mechanisms critical CSC population maintenance have been exploited therapeutic development. We developed a spatially resolved loss-of-function screen in GBM patient-derived organoids to identify essential epigenetic regulators the SOX2-enriched, therapy resistant niche and identified WDR5 as indispensable...
OBJECTIVES/GOALS: Glioblastomas (GBMs) are heterogeneous, treatment-resistant tumors that driven by populations of cancer stem cells (CSCs). In this study, we perform an epigenetic-focused functional genomics screen in GBM organoids and identify WDR5 as essential epigenetic regulator the SOX2-enriched, therapy resistant cell niche. METHODS/STUDY POPULATION: Despite their importance for tumor growth, few molecular mechanisms critical CSC population maintenance have been exploited therapeutic...
Abstract Glioblastomas (GBMs) are heterogeneous, treatment-resistant tumors that driven by populations of cancer stem cells (CSCs). In this study, we perform an epigenetic-focused functional genomics screen in GBM organoids and identify WDR5 as essential epigenetic regulator the SOX2-enriched, therapy resistant cell niche. Despite their importance for tumor growth, few molecular mechanisms critical CSC population maintenance have been exploited therapeutic development. We developed a...
The purpose of this paper is to concede the significance good governance and socio-economic performance different political regimes in India during time period 1996-2018. casual research design was employed using a quantitative approach construct Governance indices. In order showcase how parties performed their respective years power, study pioneers constructing index data on six worldwide indicators (WGI). These seek address concerns policymaking public audiences by operationalizing such...
Since the first case reports in Wuhan, China, SARS-CoV-2 virus took lives of &gt;6,85,000 people all around world. This single stranded RNA used Angiotensin converting enzyme 2 (ACE2) as a receptor for entry into host cell. Overexpression ACE2 is observed hypertensive, diabetic and heart patients that make them prone to COVID-19 infection. All world, mitigations strategies were opted by governments minimize transmission via implementation social distancing norms, wearing facemasks,...
Abstract Glioblastoma (GBM) progression and resistance to conventional therapies is driven in part by cells within the tumor with stem cell properties including quiescence, self-renewal drug efflux potential. It thought that eliminating these cancer (CSCs) a key component successful clinical management of GBM. However, currently, few known molecular mechanisms driving CSCs can be exploited for therapeutic development. Core transcription factors such as SOX2, OLIG2, OCT4 NANOG maintain CSC...