A5016680883- Advanced biosensing and bioanalysis techniques
- Biosensors and Analytical Detection
- Electrochemical Analysis and Applications
- Advanced Nanomaterials in Catalysis
- Electrochemical sensors and biosensors
- Microfluidic and Capillary Electrophoresis Applications
- Crystallization and Solubility Studies
- X-ray Diffraction in Crystallography
- Analytical Chemistry and Sensors
- Advanced Photocatalysis Techniques
- Nanocluster Synthesis and Applications
- Hydrocarbon exploration and reservoir analysis
- Gold and Silver Nanoparticles Synthesis and Applications
- Molecular Junctions and Nanostructures
- Hydraulic Fracturing and Reservoir Analysis
- RNA Interference and Gene Delivery
- Carbon and Quantum Dots Applications
- Advanced Biosensing Techniques and Applications
- Polyoxometalates: Synthesis and Applications
- Microfluidic and Bio-sensing Technologies
- Metal-Organic Frameworks: Synthesis and Applications
- MXene and MAX Phase Materials
- Nanoplatforms for cancer theranostics
- Antibiotics Pharmacokinetics and Efficacy
- MicroRNA in disease regulation
Xinyang Normal University
2016-2025
Ministry of Education of the People's Republic of China
2025
Northwest University
2025
Research Institute of Petroleum Exploration and Development
2017-2022
Xidian University
2022
Jiangsu Normal University
2022
Xinyang College of Agriculture and Forestry
2014-2021
Qingdao University of Science and Technology
2021
Nanjing University
2012-2015
The design of an ideal drug delivery system with targeted recognition and zero premature release, especially controlled specific release that is triggered by exclusive endogenous stimulus, a great challenge. A traceable aptamer-targeted nanocarrier has now been developed; the was obtained capping mesoporous silica-coated quantum dots programmable DNA hybrid, microRNA. Once nanocarriers had delivered into HeLa cells aptamer-mediated endocytosis, overexpressed miR-21 served as key to unlock...
This article describes a multimodified core–shell gold@silver nanoprobe for real-time monitoring the entire autophagy process at single-cell level. Autophagy is vital understanding mechanisms of human pathologies, developing novel drugs, and exploring approaches controlling. A major challenge study lies in monitoring. One solution might come from detection situ superoxide radicals (O2•–), because it main regulator autophagy. In this work, our proposed nanoprobes were etched by O2•– gave...
The detection of biomarkers with high sensitivity and accuracy in real biosamples remains challenging. Herein, a universal spatial-resolved photoelectrochemical (PEC) ratiometry for biodetection prostate-specific antigen (PSA) as model biomarker was designed the first time based on dual-electrode array modified by CdS@g-C3N4 heterojunction coupled CuS quantum dots (QDs) signal amplification tags. Specifically, new kind photoactive material, p–n photoelectric conversion efficiency good...
To achieve high sensitivity for biomolecule detection in photoelectrochemical (PEC) bioanalysis, the ideal photoelectrode and ingenious signaling mechanism play crucial roles. Herein, feasibility of photogenerated hole-induced chemical-chemical redox cycling amplification strategy on a Z-scheme heterostructure was validated, toward enhanced multiple signal advanced PEC immunoassay application developed. Specifically, direct Bi2S3/Bi2MoO6 synthesized via classic hydrothermal method served as...
As one of the interesting signaling mechanisms, in situ growth reaction on a photoelectrode has proven its powerful potential photoelectrochemical (PEC) bioanalysis. However, specific interaction between species with photoactive materials limits general application signal mechanism. Herein, basis an single-atom-based material, PEC immunoassay was developed split-type mode consisting immunoreaction and detection procedure. Specifically, single-atom material that incorporates Fe atoms into...
It is valuable to develop a sensing platform for not only detecting tumor marker in body fluids but also measuring its expression at single cells. In the present study, simple closed bipolar electrodes-based electrochemiluminescence (BPEs-ECL) imaging strategy was developed visual immunoassay of prostate specific antigen (PSA) cells using functional nanoprobes heterogeneous Ru(bpy)32+@SiO2/Au nanoparticles. Multiple-assisted ECL signal amplification introduced into detection system on basis...
Signal amplification is essential for ultrasensitive photoelectrochemical (PEC) bioanalysis. Exploration of the facile and efficient route multiple signal highly appealing. Herein, we present concept photoelectrochemical-chemical-chemical (PECCC) redox cycling as an advanced a proof-of-concept toward PEC The system operated upon bridging between enzymatic generation signaling species ascorbic acid (AA) from sandwich immunoassay PECCC among ferrocenecarboxylic mediator, AA,...
This work reports the elegant bridging of enzymatic generation electron donor with photogenerated hole-induced chemical redox cycling amplification (RCA) for innovative photoelectrochemical (PEC) immunoassay, by aid a heterojunction photoelectrode split-type strategy. Specifically, system was exemplified alkaline phosphatase (ALP) catalytic ascorbic acid (AA), AA tris (2-carboxyethyl) phosphine (TCEP) as reductant, and use novel Bi2S3/Bi2Sn2O7 myoglobin (Myo) target, respectively. After...
Novel exciton–plasmon interactions (EPI) between CdS@g-C3N4 heterojunction and Au@Ag nanoparticles (NPs) was introduced for the first time into photoelectrochemical (PEC) biosensing system highly sensitive microRNA-21 detection using duplex-specific nuclease-assisted cycle amplification sensitivity enhancement. The photoelectrode of nanowires could generate a great photocurrent because formation p–n heterojunction. Due to natural absorption overlap, exciton plasmon NPs be induced...
A facile label-free electrochemiluminescence aptasensor based on cadmium sulfide–graphene nanocomposites was designed for the detection of carcinoembryonic antigen.
Abstract The design of an ideal drug delivery system with targeted recognition and zero premature release, especially controlled specific release that is triggered by exclusive endogenous stimulus, a great challenge. A traceable aptamer‐targeted nanocarrier has now been developed; the was obtained capping mesoporous silica‐coated quantum dots programmable DNA hybrid, microRNA. Once nanocarriers had delivered into HeLa cells aptamer‐mediated endocytosis, overexpressed miR‐21 served as key to...
A ferrocenecarboxylate-functionalized titanium-oxo cluster [Ti<sub>6</sub>(μ<sub>3</sub>-O)<sub>6</sub>(OiPr)<sub>6</sub>(O<sub>2</sub>CFc)<sub>6</sub>] was synthesized, in which the ferrocene wheel performs as a sensitizer for photocurrent response.