A5100344008- Parkinson's Disease Mechanisms and Treatments
- Sleep and Wakefulness Research
- Intracerebral and Subarachnoid Hemorrhage Research
- Sleep and related disorders
- Neuroblastoma Research and Treatments
- Intracranial Aneurysms: Treatment and Complications
- Neurosurgical Procedures and Complications
- Vascular Malformations Diagnosis and Treatment
- Moyamoya disease diagnosis and treatment
- Nuclear Receptors and Signaling
- Cancer therapeutics and mechanisms
- COVID-19 Clinical Research Studies
- Myasthenia Gravis and Thymoma
- Cerebrospinal fluid and hydrocephalus
- Ginkgo biloba and Cashew Applications
- Long-Term Effects of COVID-19
- Neurological disorders and treatments
- Cancer, Hypoxia, and Metabolism
- Restless Legs Syndrome Research
- Intensive Care Unit Cognitive Disorders
- Amyotrophic Lateral Sclerosis Research
- Retinoids in leukemia and cellular processes
- Retinal Diseases and Treatments
- Selenium in Biological Systems
- Axon Guidance and Neuronal Signaling
Inner Mongolia Agricultural University
2025
Nanjing Second Hospital
2025
Sichuan University
2018-2023
West China Hospital of Sichuan University
2018-2023
Union Hospital
2015-2023
Huazhong University of Science and Technology
2015-2023
Hebei Medical University
2022
Second Hospital of Hebei Medical University
2022
Zhongda Hospital Southeast University
2022
Columbia University
2021
Recent researches regarding to exosomal involvement in alpha-synuclein (α-syn) transmission relating the pathological process of Parkinson's disease (PD) have attracted considerable attention. It is highly desirable make clear diffusion and cellular uptake α-syn-associated exosomes underlying mechanism exosomes-involved communication synucleinopathy pathogenesis. To determine contribution initiation progression PD, plasma derived from PD patients were stereotaxically injected into striatum...
Camel milk is known to have hypoglycemic properties. Previous studies found that camel exosomes (CM-exo) may regulate cellular glucose metabolism through the inhibition of mitochondrial complex I, but this hypothesis has not been verified by other experiments. The objective study was verify CM-exo regulated in hepatocytes inhibiting I pathway. AML12 cells were treated with extracted from and effect on cell viability examined counting kit (CCK)-8 assays. content culture medium measured...
Current research predominantly emphasizes the impact of diet on sleep, while overlooking role oxidative effects influenced by lifestyle factors. The Oxidative Balance Score (OBS) provides a comprehensive measure individual overall stress exposure, integrating 16 dietary nutrients and 4 factors that affect processes. To explore relationship between OBS sleep-related problems, data from National Health Nutrition Examination Survey (NHANES) conducted 2005 2008 were utilized for cross-sectional...
(1) Background: Parkinson's disease (PD) is the most common movement disorder. Imbalanced protein homeostasis and α-syn aggregation are involved in PD pathogenesis. Autophagy related to occurrence development of can be regulated by histone deacetylases (HDACs). Various inhibitors HDACs exert neuroprotective effects within vitro vivo models PD. HDAC4, a class Ⅱ HDAC, colocalizes with α-synuclein ubiquitin Lewy bodies also accumulates nuclei dopaminergic neurons models. (2) Methods: In present...
Arsenic trioxide (As2O3), a drug that has been used in China for approximately two thousand years, induces cell death variety of cancer types, including neuroblastoma (NB). The tyrosine kinase receptor (Trk) family comprises three members, namely TrkA, TrkB and TrkC. Various studies have confirmed TrkA TrkC expression is associated with good prognosis NB, while overexpression can lead to tumor growth invasive metastasis. Previous shown As2O3 inhibit the proliferation human NB line also...
Traditional Chinese medicine (TCM) non-pharmaceutical therapies are frequently used for chronic insomnia in China, but clinical practice, most practitioners choose appropriate treatments based on personal experience. In our study, Bayesian network meta-analysis will be to identify differences efficacy and safety between diverse adult insomnia.
Patients with essential tremor (ET) syndrome have more prevalent and serious gait balance impairments than healthy controls. In this cross-sectional study, we explored whether are associated falls as well pronounced non-motor symptoms in patients ET syndrome.We assessed the tandem (TG) test, or near-falls that occurred over previous year. Non-motor symptoms-including cognitive deficits, psychological sleep disorders-were evaluated. univariate analyses, statistical significance was corrected...
Traditional Chinese medicine (TCM) has gradually drawn the attention of clinicians as an alternative choice for insomniacs and TCM yangxin anshen therapy (TYAT), a crucial treating insomniacs, is based on theory syndrome differentiation. However, owing to lack evidence-based medical evidence, authors intend carry out this study evaluate TYAT's effectiveness safety.Seven electronic databases will be searched from inception July 2019. Two independently identify randomized controlled trials,...
Neuroblastoma (NB) is one of the most common extracranial, solid, pediatric malignancies. Despite improvements in conventional therapies, including surgery, chemotherapy and radiation therapy, prognosis stage IV NB remains poor, indicating that novel treatment strategies are required. Immunotherapies, such as anti‑GD2 monoclonal antibodies, used alone or combination with cytokines, peripheral blood mononuclear cells cord (CBMNCs), have been indicated to cause cell death prolong patient...
Background: We conducted this study to assess the value of clinically relevant data for predicting failure removing urinary catheters among patients with intracerebral hemorrhage postoperatively. Materials and Methods: retrospectively analyzed medical records all who underwent surgery removal hematoma between January 2014 December 2019, whom retained their catheter. The were classified into 2 groups. Group A included successful catheter while group B a failed removal. Univariate analysis was...
Intracranial aneurysms associated with cerebral arteriovenous malformations (AVMs) are a rare condition in the clinic, and treatment is very difficult due to their particular anatomical features. We present our experience of intracranial AVMs evaluate effectiveness safety endovascular combined microsurgical resection (the hybrid operation).This was single-center retrospective study neurosurgical department from January 2015 2021. collected clinical data 48 patients categorized them according...
Objective To evaluate the efficacy and safety of intensive blood pressure control for patients with intracerebral hemorrhage (ICH). Methods Retrieve relevant randomized controlled trials (RCTs) from online databases (January 1, 1980-September 30, 2015) as PubMed, EBMASE/SCOPUS Cochrane Library key words: hemorrhage, ICH, pressure, intensive, acute. Selection studies was performed according to pre-designed inclusion and exclusion criteria. Quality evaluated by using Jadad Scale. All data were...