- Insect Resistance and Genetics
- Insect and Pesticide Research
- Biotin and Related Studies
- Entomopathogenic Microorganisms in Pest Control
- Genetically Modified Organisms Research
- Insect Pest Control Strategies
- CRISPR and Genetic Engineering
- Gun Ownership and Violence Research
- Lymphoma Diagnosis and Treatment
- Plant and animal studies
- Ear and Head Tumors
- Insect-Plant Interactions and Control
- Injury Epidemiology and Prevention
- CNS Lymphoma Diagnosis and Treatment
- Rabies epidemiology and control
- Chronic Lymphocytic Leukemia Research
- Chronic Myeloid Leukemia Treatments
- Eosinophilic Disorders and Syndromes
Middlemore Hospital
2022
Brooke Army Medical Center
2009-2016
Michigan State University
2004-2015
Monsanto (United States)
2015
Texas A&M University
2015
ABSTRACT Soybean aphid ( Aphis glycines Matsumura) is a native pest of soybean [ Glycine max (L.) Merr.] in eastern Asia and was detected on soybeans North America 2000. In 2004, the cultivar Dowling described to be resistant aphids with Rag1 gene for resistance. 2006, virulent biotype Ohio reported proliferate gene. The objective survey occurrence populations indicator lines across geographies years. Nine were identified basis their degree resistance importance breeding programs. Naturally...
Abstract The sustainable deployment of resistant crop varieties is a critical issue for the implementation biotechnology in pest management. Feeding, biomass accumulation, and mortality were evaluated susceptible, insecticide‐resistant, Bacillus thuringiensis (Bt) Cry 3A‐selected Colorado potato beetle ( Leptinotarsa decemlineata Say) (Coleoptera, Chrysomelidae) larvae fed on: cultivated potato, Solanum chacoense line expressing leptine glycoalkaloids, transformed Bt toxin, or to express...
Colorado potato beetle, Leptinotarsa decemlineata (Say), is a destructive pest of potato, Solanum tuberosum (L.), in North America. It renowned for adapting to insecticides. With the arsenal effective insecticides decreasing, it important consider alternative forms control. Biotin an essential coenzyme insect growth and development. Avidin protein found chicken egg that sequesters biotin has shown insecticidal properties against range insect. We assessed effectiveness avidin beetle neonates...
The potato tuberworm [ Phthorimaea operculella (Zeller)] is one of the most destructive insect pests to ( Solanum tuberosum L.) in tropical and subtropical regions, it has recently become established Pacific Northwest United States. Combining natural resistance mechanisms with Bacillus thuringiensis Bt ) cry genes could be a potential solution improve tuberworm. We have expressed cry1Ac two lines: Spunta, susceptible line, ND5873-15, moderately resistant line high foliar glycoalkaloids...
The Colorado potato beetle, Leptinotarsa decemlineata (Say) (Coleoptera: Chrysomelidae), is the most destructive insect pest of potato, Solanum tuberosum (L.), in North America. Avidin sequesters available biotin, thereby causing abnormal growth and development insects. We expressed avidin two lines: MSE149-5Y, a susceptible line, ND5873-15, line with S. chacoense-derived resistance. A preliminary study was conducted to determine bioactivity transgene each background. single transgenic...
Non-Hodgkin lymphomas (NHLs) are a heterogeneous group of hematologic malignancies which typically respond to standard first-line chemoimmunotherapy regimens. Unfortunately, patients with refractory NHL face poor prognosis and represent an unmet need for improved therapeutics. We present two cases CD30+ who responded novel brentuximab vedotin- (BV-) based The first is patient stage IV anaplastic large cell lymphoma (ALCL) cranial nerve involvement failed front-line treatment...
The Colorado potato beetle, Leptinotarsa decemlineata Say, is the major insect pest of potato, Solanum tuberosum L., in eastern North America and renowned for resistance development, currently resistant to >40 insecticides worldwide. Host plant may assist delaying development insecticides. We evaluated natural host mechanisms (glandular trichomes chacoense Bitter-derived resistance) engineered (Bacillus thuringiensis [Bt] Berliner cry3A cry1Ia1) a no-choice cage study. Six different lines...
Colorado potato beetle, Leptinotarsa decemlineata (Say), is a destructive pest of potato, Solanum tuberosum (L.), in North America. It renowned for adapting to insecticides. With the arsenal effective insecticides decreasing, it important consider alternative forms control. Biotin an essential coenzyme insect growth and development. Avidin protein found chicken egg that sequesters biotin has shown insecticidal properties against range insect. We assessed effectiveness avidin beetle neonates...
Colorado potato beetle ( Leptinotarsa decemlineata Say) is the leading insect pest of Solanum tuberosum L.) in northern latitudes. Host plant resistance an important tool integrated management program for controlling pests. Field studies were conducted to compare natural host mechanisms (glandular trichomes and chacoense Bitter-derived resistance), engineered [ Bacillus thuringiensis Bt ) Berliner Bt-cry3A ], combined + S. -derived transgenic lines) sources control colorado beetle. Six...