A5020421885- Shoulder Injury and Treatment
- Hip disorders and treatments
- Knee injuries and reconstruction techniques
- Sports injuries and prevention
- Orthopaedic implants and arthroplasty
- Exercise and Physiological Responses
- Tendon Structure and Treatment
- Muscle Physiology and Disorders
- Medical research and treatments
- Winter Sports Injuries and Performance
- Osteoarthritis Treatment and Mechanisms
- Musculoskeletal Disorders and Rehabilitation
- Sports Performance and Training
- Muscle activation and electromyography studies
- Lower Extremity Biomechanics and Pathologies
- Cardiac Valve Diseases and Treatments
- Muscle metabolism and nutrition
- Thermoregulation and physiological responses
- Neurogenetic and Muscular Disorders Research
- Hematological disorders and diagnostics
- Shoulder and Clavicle Injuries
- Musicians’ Health and Performance
- Total Knee Arthroplasty Outcomes
University of Michigan
2013-2022
Hospital for Special Surgery
2020
Michigan Medicine
2014
Background: In the diagnosis and surgical treatment of cam-type femoroacetabular impingement (FAI), 3-dimensional (3D) imaging is gold standard for detecting femoral head-neck junction malformations preoperatively. Intraoperative fluoroscopy used by many surgeons to evaluate verify adequate correction deformity. Purpose: (1) To compare radial reformatted computed tomography (CT) scans with 6 defined intraoperative fluoroscopic views before determine whether could adequately depict cam...
Background: After anterior cruciate ligament (ACL) reconstruction, there is significant atrophy of the quadriceps muscles that can limit full recovery and place athletes at risk for recurrent injuries with return to play. The cause this muscle not fully understood. Hypothesis: Circulating levels proatrophy, proinflammatory, cartilage turnover cytokines biomarkers would increase after ACL reconstruction. Study Design: Descriptive laboratory study. Methods: Patients (N = 18; mean age, 28 ± 2.4...
Background: Femoroacetabular impingement (FAI) is one of the most common causes early cartilage and labral damage in nondysplastic hip. Biomarkers degradation inflammation are associated with osteoarthritis. It was not known whether patients FAI have elevated levels biomarkers inflammation. Hypothesis: Compared athletes without FAI, would inflammatory C-reactive protein (CRP) oligomeric matrix (COMP), a marker. Study Design: Controlled laboratory study. Methods: Male radiographically...
ABSTRACT Introduction : Patients with anterior cruciate ligament (ACL) tears have persistent quadriceps strength deficits that are thought to be due altered neurophysiological function. Our goal was determine the changes in muscle fiber contractility independent of ability motor neurons activate fibers. Methods We obtained biopsies patients undergoing ACL reconstruction, and additional 1, 2, 6 months after surgery. Muscles assessed vitro , along whole testing. Results Compared controls, had...
Cryotherapy is commonly used in the treatment of skeletal muscle injuries. However, data to support use cryotherapy inconclusive, and biochemical etiology human remains largely unknown. We therefore sought determine how a clinically-relevant dose would impact transcriptome metabolome muscle. Eight healthy male subjects (age 24.7 ± 4.5 years, BMI 22.2 1.6) received 15 minute bout local cryotherapy, delivered via ice cup massage over anterolateral thigh. This resulted an 85% decrease skin...
Background: Tendons are viscoelastic tissues that deform (elongate) in response to cyclic loading. However, the ability of a tendon recover this elongation is unknown. Hypothesis: Tendon length significantly increases after vivo or vitro loading, and return its original through cell-mediated contraction mechanism an age-dependent phenomenon. Study Design: Controlled laboratory study. Methods: In vitro, rat tail fascicles (RTTfs) from Sprague-Dawley rats 3 age groups (1, 3, 12 months)...
Background: Anterior cruciate ligament (ACL) tears are common knee injuries. Despite undergoing extensive rehabilitation after ACL reconstruction (ACLR), many patients have persistent quadriceps muscle weakness that limits their successful return to play and also at an increased risk of developing osteoarthritis (OA). Human growth hormone (HGH) has been shown prevent atrophy in various models disuse disease but not evaluated ACLR. Hypothesis: Compared with placebo treatment, a 6-week...
Objectives: A common pathophysiological change that occurs in torn rotator cuff muscles is atrophy of muscle fibers and an accumulation intramuscular fat, collectively referred to as "fatty degeneration." For many patients with chronic tears undergo surgical repair, fatty degeneration not resolved. The etiology has been characterized humans, gaining greater insight into the mechanisms lead development fat will likely improve recovery who repair a cuff. purpose this study was gain...
Cryotherapy is a commonly used therapeutic modality for skeletal muscle injuries in sports medicine. Despite the widespread use of this modality, there little known about biochemical effects cryotherapy human tissue humans. PURPOSE: To determine has on transcriptome and metabolome muscle. METHODS: Using paired design, 8 healthy male subjects (mean age 24.7 years, mean BMI 22.2) received ice-cup massage or sham cup over 45 cm2 area each thigh 15 min. Two hours after application, bilateral...
Objectives: Patients with Femoroacetabular impingement (FAI) have been shown to elevated circulating biomarkers of inflammation and cartilage catabolism, but little is known about whether corrective surgical intervention improves objective measures hip strength inflammation. This study measured several variables including pain, function, quality life, symptoms, strength, inflammatory in a cohort subjects undergoing FAI surgery postoperative (postop) rehabilitation. We hypothesized that...
Background: Patients with symptomatic femoroacetabular impingement (FAI) have hip strength deficits, instability, and increased risk for concomitant injury. While surgical intervention is an effective method of treatment FAI, more information needed about the recovery process. Purposes: We sought to understand how patients FAI recover from correction in short term. Do patients’ perceptions improvement correspond measured improvements strength? Methods: conducted a prospective cohort study 17...