A5019354309- Electrospun Nanofibers in Biomedical Applications
- Advanced Cellulose Research Studies
- Phytochemicals and Antioxidant Activities
- Natural Antidiabetic Agents Studies
- Hibiscus Plant Research Studies
- Silk-based biomaterials and applications
- Polysaccharides Composition and Applications
- Psidium guajava Extracts and Applications
- Polysaccharides and Plant Cell Walls
- Hydrogels: synthesis, properties, applications
- Synthesis and biological activity
- Moringa oleifera research and applications
- Bioactive natural compounds
- Synthesis and bioactivity of alkaloids
- 3D Printing in Biomedical Research
- Ultrasound and Hyperthermia Applications
- Advanced Sensor and Energy Harvesting Materials
- Bioactive Compounds in Plants
- Bee Products Chemical Analysis
- Tannin, Tannase and Anticancer Activities
- Wound Healing and Treatments
- Bone Tissue Engineering Materials
- Traditional and Medicinal Uses of Annonaceae
- Bioactive Compounds and Antitumor Agents
- Laser Applications in Dentistry and Medicine
University of Technology Malaysia
2015-2024
World Cancer Research Fund International
2017
Christian Medical College & Hospital
2012
University of Birmingham
2011
Banaras Hindu University
2009
Universiti Putra Malaysia
2007-2008
Jinan University
1987
Alginate hydrogels have been used widely in tissue engineering for cell encapsulation several reasons: low toxicity, the ability to gel under gentle condition and compatibility with cells. In this study, we determined effect of different conc
Delphinidin 3-sambubioside compound (Dp-3-sam) (patent number MY-193036-A) could be effective against diabetes. Results showed that Dp-3-sam caused BRIN BD11, 3T3F442A, L6 myoblast and HSF 1184 cells to become significantly less viable after three days incubation. By comparison positive control, in 50 µg/ml significant inhibitory effects 96.76% (p<0.05). Glucose diffusion was diminished by concentration (4.98 mmol/L; p<0.01) compared control (6.85 p<0.05). With regard wound healing,...
Herbal medicines play an important role in modern human life and have significant effects on treating diseases; however, the quality safety of these herbal products has now become a serious issue due to increasing pollution air, water, soil, etc. The present study proposes Fourier transform infrared spectroscopy (FTIR) along with statistical method principal component analysis (PCA) identify discriminate for control. plants been characterized using FTIR spectroscopy. Characteristic peaks...
Justicia gendarussa methanolic leaf extracts from five different locations in the Southern region of Peninsular Malaysia and two flavonoids, kaempferol naringenin, were tested for cytotoxic activity. Kaempferol naringenin flavonoids detected using gas chromatography-flame ionization detection (GC-FID). The results indicated that highest concentrations leaves extracted Mersing with 1591.80 mg/kg 444.35 mg/kg, respectively. Positive correlations observed between all analysed Pearson method....
Alginate is an interesting natural biopolymer to be considered for biomedical applications due its advantages and good biological properties. These properties make electrospun alginate nanofibers suitable various uses in the field, such as wound healing dressings, drug delivery systems, or both. Unfortunately, fabrication of by electrospinning very challenging because high viscosity solution, surface tension rigidity water hydrogen bonding, also their diaxial linkages. This review presents...
The present study was designed to evaluate the cytotoxic activity of Justicia gendarussa methanolic leaf extracts from five different locations in Johor and also two standards flavonoids (naringenin kaempferol) as these compounds were detected chromatogram. In this study, tested against various human cancer cell lines (HT-29, HeLa BxPC-3) by using MTT assay. results showed that Mersing kaempferol very toxic BxPC-3 cells with IC50 values 16 µg/ml 5 µg/ml, respectively. It is suggested J. have...
Abstract The aim of this study is to evaluate the optimum sodium hydroxide (NaOH) concentrations (2 12 wt%) for extraction cellulose from agricultural waste – rice straw fiber towards preparation cellulose‐based hydrogel. increase in weight loss with increasing alkaline concentration, suggested that delignification took place progressively up 6 wt% NaOH as supported by reduction color intensity and chemical analysis using Fourier transform infrared spectroscopy (FTIR). After extraction, was...
To provide in vitro evidence for antidiabetic activity through potential inhibition of α-glucosidase enzyme, glucose diffusion and enhancement the wound healing using methanolic extract fractions from Hibiscus sabdariffa Linn. fruit. The inhibitory action such fruit on enzyme movement assay assessment was reported. Their activities were tested scratch assay. Ethyl acetate fraction at 50 mg/mL concentration exhibited significant (95.79 mg/mL) with P < 0.05. At same concentration, as well...
This study was carried out to observe prescription pattern of anti depressants as well other psychotropic medications for the treatment depression. A sample 100 adult patients selected participate in study. First five depression (with or without psychotic symptoms) from twenty patient departments (OPDs) various consultant psychiatrists Department Psychiatry, C. S. M. Medical University, Lucknow, were included with sample. It found that a large number (84%) co-prescribed Clonazepam. observed...
In this study, methanolic extracts of 14 traditional plants in Malaysia were screened for insulinotrophic properties, using rat pancreatic B-cell lines, BRIN-BD11 cells.In 30min acute static incubation test, all showed varying degree responsivess insulin release with Labisa pumila, Morinda charantia and Tinospora crispa having high activities.These also displayed appreciably low cyotoxic results show a promising avenue development novel secretagogues.
The effect of laser wavelength on gold nanoparticle fabrication is reported. Colloidal solutions nanoparticles were prepared by pulsed ablation technique in deionized water. A Q-switched Nd:YAG with constant energy 65mJ and operation at fundamental second harmonic generation was utilized as a source energy. Fabricated particles characterized using Smart Nanoparticles Measurements (SNM) system. average diameters achieved as19 nm 12 corresponding to 1064 532 respectively. fragmentation...
Orthosiphon aristatus (Blume) Miq. is traditionally used for wound healing in South East Asia and scientifically proven its antidiabetic potential. Wounds due to diabetes, especially diabetic foot ulcer (DFU), always involve a complicated process. The present work aims review the information on rationale of phytochemicals from O. promoting DFU healing. findings showed that potential was characterized by reduction blood glucose level, mainly attributed significant concentration constituents...
A series of heterocyclic chalcone (3a–e, 5, 7) were synthesized and characterized by Infrared, 1H 13C nuclear magnetic resonance, mass spectra. Crystal structure 1-(4-iodophenyl)-3-(5-methylfuran-2-yl)prop-2-en-1-one was determined using single crystal X-ray diffraction. All the compounds evaluated for their cytotoxic activities on MDA MB 231 CHO cell MTT assay. Compound 3c showed good effect with IC50 values 9.8 µg/mL.
Cancers are diseases that can cause death and breast cancer is one of the prevalence cancers. Conventional treatments have been used to treat cancer. However, these produced inefficient effects low survival rate. Therefore, most patients began consume complementary utilized alternative alleviate their pain. This study identify cytotoxicity effect methanolic leaves extract Typhonium flagelliforme Clinacanthus nutans on cells (MDA-MB-231). MTT assay has determine both plants MDA-MB-231 CHO...
Over the last few decades, use of agro by-products as a biopolymer for various applications has attracted significant interest researchers. Rice husk (RH) is one produced abundantly worldwide and great deal studies in extracting utilizing silica from RH have been reported but scarcely its cellulose components. A specific study on utilization extracted electrospinning process also remains unreported. Chemical pre-treatment seems to be most crucial step which improves elimination cementing...
Justicia gendarussa methanolic leaves extract from four different locations in Southern region of Malaysia and distribution two flavonoids, naringenin kaempferol plant organs (young mature leaves) were determined using gas chromatography-flame ionization detector (GC-FID) analysis.Naringenin contents detected quantified extract.The results indicated that contained more compared to young leaves.The highest concentration recorded Skudai Muar regions which 507.692 1226.964mgkg -1 ,...
According to the World Cancer Research Fund International (WCRFI), breast cancer is most common type of in women worldwide with recorded 1.7 million new cases 2012.The main line treatments still limited chemotherapy, surgery and radiotherapy which could lead a wide range dangerous side effects.This study was conducted evaluate effect low intensity ultrasound (LIUS) on cell proliferation, percentage living dead cells induction apoptosis MCF-7 CHO as control for non-cancerous group.In order...