A5032876913- Chronic Lymphocytic Leukemia Research
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Acute Myeloid Leukemia Research
- Multiple Myeloma Research and Treatments
- Chronic Myeloid Leukemia Treatments
- Platelet Disorders and Treatments
- Immunodeficiency and Autoimmune Disorders
- Hematopoietic Stem Cell Transplantation
- Eosinophilic Disorders and Syndromes
- Neutropenia and Cancer Infections
- Blood disorders and treatments
- Blood groups and transfusion
- Central Venous Catheters and Hemodialysis
- Monoclonal and Polyclonal Antibodies Research
- Venous Thromboembolism Diagnosis and Management
- Acute Lymphoblastic Leukemia research
- Kruppel-like factors research
- Heparin-Induced Thrombocytopenia and Thrombosis
- Helicobacter pylori-related gastroenterology studies
- Hemoglobinopathies and Related Disorders
- Iron Metabolism and Disorders
- Hematological disorders and diagnostics
- Extracellular vesicles in disease
- Glutathione Transferases and Polymorphisms
- Immunotoxicology and immune responses
Ospedale Valduce
2007-2024
University of Chieti-Pescara
2021
Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico
2011-2019
Hospital Clínico de la Universidad de Chile
2018
University of Milan
2011-2017
Ospedale Maggiore
2012-2017
Istituti di Ricovero e Cura a Carattere Scientifico
2012
Invasive fungal infections (IFIs) are a leading cause of morbidity and attributable mortality in oncohematologic patients. Timely diagnosis is essential but challenging. Herein we retrospectively describe 221 cases antifungal treatments (AFT) administered monocentric real-life cohort hematological malignancies. Between January 2010 July 2017, 196 patients were treated with AFT at our Hematology Department. Diagnosis IFIs was carried out according to EORTC/MSG-2008 guidelines.The most...
Acute treatment of menstrual migraine (MM) attacks is often incomplete and unsatisfactory, perimenstrual prophylaxis with triptans, oestrogen supplementation or naproxen sodium may be needed for decreasing frequency severity the attack. In this pilot, open-label, non-randomised, parallel group study we evaluated, in 38 women a history MM, efficacy frovatriptan (n=14) 2.5 mg per os transdermal oestrogens (n=10) 25 μg 500 once-daily short-term prevention MM. All treatments were administered...
Abstract Introduction Ixazomib, lenalidomide, and dexamethasone (IRd) have been approved for the treatment of relapsed/refractory multiple myeloma (RRMM) based on results TOURMALINE‐MM1. Objectives Methods We conducted a retrospective–prospective analysis 106 RRMM patients (pts) treated with IRd in 21 centers Northern Italy, aim to evaluate efficacy safety real life. Results At initiation, 34% pts were aged ≥75 (median 72.5), 8.5% had an ECOG performance status ≥2, 54.7% evaluable carried...
Although pulmonary function abnormalities in thalassaemia major (TM) were described 1980, the pathogenetic mechanism is not clear and data are contradictory, probably because of study heterogeneity multifactorial nature pathogenesis. We retrospectively analysed 73 adult TM patients to evaluate prevalence dysfunction investigate relationships with iron load. All underwent body plethysmography carbon monoxide diffusion (DLCO) was assessed 63, addition blood tests, echocardiogram T2* myocardial...
Chronic lymphocytic leukemia (CLL) is frequently complicated during its course by autoimmune disorders (from 2 to 12% of cases), such as hemolytic anemia (AIHA) and immune thrombocytopenic purpura (ITP). In particular, ITP has been reported in about 2–5% CLL population. Recently, Cuker et al. the occurrence 6/216 patients with relapsing-remitting multiple sclerosis a phase clinical trial annual alemtuzumab. Alemtuzumab an anti-CD52 monoclonal antibody used both first-line treatment...
Background: Helicobacter pylori (HP) is the most widespread chronic human infection worldwide and important pathogenic factor of gastric cancer. The calculated prevalence at Clinical Hospital University Chile from 2002 to 2005 was 44.9%.
Introduction Chronic myeloid leukemia (CML) is a malignant clonal disorder of hematopoietic stem cells characterized by translocation genetic material between chromosomes 9 and 22 resulting in the BCR-ABL fusion oncogene expression. Nilotinib potent second-generation tyrosine kinase inhibitor available as first line treatment. Among side effects QTc interval prolongation, pancreatitis, metabolic disorders skin reactions are most commonly seen. Case Report Here we describe rare case lichen...