A5079028544- Prostate Cancer Treatment and Research
- Estrogen and related hormone effects
- Hormonal and reproductive studies
- Medical Imaging and Pathology Studies
- Gastric Cancer Management and Outcomes
- Pediatric Urology and Nephrology Studies
- Bladder and Urothelial Cancer Treatments
- Venous Thromboembolism Diagnosis and Management
- Metastasis and carcinoma case studies
- Catalysis and Hydrodesulfurization Studies
- Cerebral Venous Sinus Thrombosis
- Neuroendocrine Tumor Research Advances
- Zeolite Catalysis and Synthesis
- Cardiac tumors and thrombi
- Neurological and metabolic disorders
- Bone health and treatments
- Esophageal and GI Pathology
- Urinary Bladder and Prostate Research
- Developmental Biology and Gene Regulation
- Urinary and Genital Oncology Studies
- Spine and Intervertebral Disc Pathology
- Catalysis for Biomass Conversion
- Prostate Cancer Diagnosis and Treatment
- Urologic and reproductive health conditions
- Esophageal Cancer Research and Treatment
University of Yamanashi
2021
Tachikawa Hospital
2021
Tonami General Hospital
2021
Niigata Prefectural Central Hospital
2018-2020
Niigata City General Hospital
2015-2017
Niigata University
2009-2017
Kumamoto University Hospital
2014
Kumamoto University
2010-2013
Research Institute for Bioscience and Biotechnology
2013
Kitasato University
2007
Frequencies of voiding and urinary incontinence are commonly measured by a patient's recall or diary. The recommended diary length varies from 1 to 14 days, with 7 days apparently being most common. To examine the statistical precision these different modalities, we analyzed data 74 patients frequency, incontinence, both. Recall on frequency were systematically higher more variable than data. Longer provided less confidence interval was calculated applying normal distribution daytime Poisson...
The present study was undertaken to determine whether asbestos exposure induces the formation of nitric oxide (NO.) radical by rat alveolar macrophages (AM). For this purpose, AM from Sprague-Dawley rats were cultured for 48 h in presence or absence either chrysotile (serpentine) crocidolite (amphibole) fibers. effects fibers compared with those nonfibrogenic carbonyl iron particles. Nitrite (NO2-), stable oxidation product NO. macrophage conditioned medium, assayed Griess reaction....
Danforth's short tail (Sd) is a semidominant mutation on mouse chromosome 2, characterized by spinal defects, urogenital and anorectal malformations. However, the gene responsible for Sd phenotype was unknown. In this study, we identified molecular basis of mutation. By positional cloning, insertion an early transposon in candidate locus approximately 12-kb upstream Ptf1a. We found that caused overexpression three neighboring genes, Gm13344, Gm13336, Ptf1a, mutant embryos not disruption...
Transurethral double J (DJ) stent placement is a standard method for drainage during ureteral obstruction caused by stone and the management of complications after transurethral ureterolithotripsy (TUL). This safe minimally invasive technique; however, severe cases DJ migration have been reported, although rarely. Herein, we report CASE 48-year-old man with as renal penetration, which arose complication an unsuccessful TUL. As one basic techniques performed urologists, possible rare should...
Hematoma of the ligamentum flavum is a rare cause neural compression, for which treatment has consisted excising hematoma via open surgical approaches, including total laminectomy or bilateral partial laminectomy. This article presents first report microscope-assisted endoscopic decompression to resect flavum.A 52-year-old man presented with back and leg pain, as well difficulty initiating micturation. Magnetic resonance imaging demonstrated an epidural mass at L5/S1 that was continuous...
Bladder cancer commonly metastasizes to the lymph nodes. Rectal obstruction (RO) caused by bladder has been reported rarely, and its underlying mechanism remains unclear. Herein, we present an autopsy case of a 67-year-old man with RO urothelial carcinoma (UC) micropapillary variant in bladder. The showed high-grade UC infiltrating rectum via bladder's lateral pedicle, widely spreading within retroperitoneum due lymphatic dissemination. Given that is typically diagnosed after it become...
Duodenal and rectal obstructions due to urological malignancies are relatively uncommon. We report an autopsy case of 83-year-old man with a history renal pelvic cancer who presented these obstructions. Autopsy revealed that urothelial infiltrated the bladder wall, duodenal prostate widely spread in retroperitoneal lymphatic vessel. concluded recurred wall then into each organ because dissemination. The gastrointestinal urinary tract were lethal. Further knowledge clinical experience...
Abstract Intratumoural dihydrotestosterone (DHT) synthesis could be an explanation for castration resistance in prostate cancer (PC). By using liquid chromatography-mass spectrometry, we evaluated the intratumoral DHT from 5α-androstane-3β,17β-diol (3β-diol), which is inactive androgen metabolized DHT. 3β-diol had biochemical potential to converted via three metabolic pathways and stimulate PC cell growth. Especially, was not only back upstream androgens such as dehydroepiandrosterone (DHEA)...
Abstract Sickle tail ( Skt ) was originally identified by gene trap mutagenesis in mice, and the trapped is highly expressed notochord, intervertebral discs (IVD), mesonephros. Here, we report generation of cre mice expressing Cre recombinase IVD due to target insertion into Sk t locus recombinase‐mediated cassette exchange. Crossing a conditional lacZ Reporter (R26R), expression from allele specifically activates β‐galactosidase whole notochord E9.5 onwards. In E15.5 ;R26R embryos, reporter...
Late-onset rectal bleeding after transrectal prostate needle biopsy is potentially life-threatening. We report the case of a 75-year-old male who presented with severe 3 days biopsy. Because could not be arrested by conservative treatment, emergent colorectal endoscopic clipping (twice) and elective angiography were performed. Packed red blood cell transfusion (14 units in total) was required to treat developed hemorrhagic shock. Colorectal endoscopy arterial embolization are effective...
Abstract Endoscopic submucosal dissection (ESD) is recognized as an important technique in the nonsurgical management of early gastrointestinal carcinoma and it continuously undergoing evolution terms equipment. The pocket-creation method was recently developed for overcoming various difficulties such large tumor size severe fibrosis ESD. Circumferential ESDs are rare pose technical difficulties. We present a case circumferential rectal ESD using with two pockets. associated planning,...
Introduction A part of hypercalcemia is a paraneoplastic syndrome. Its association with lymph node metastasis bladder cancer has been infrequently reported in the literature. Case presentation 75‐year‐old male presented gross hematuria and was diagnosed without metastasis. Following neoadjuvant chemotherapy, radical cystectomy performed. The surgical margin negative. classified as pT 3bN0 mainly constituted squamous differentiated urothelial carcinoma sarcomatoid variant. His perioperative...
Clarifying the mechanisms underlying prostate cancer (PC) progression and resistance to androgen deprivation therapy (ADT) is an urgent clinical issue. ADT influences steroidal metabolism in patients with PC promotes accumulation of carbon 21 steroids (C21s), such as progestin. Because enzymes responsible for C21s are similar those metabolism, cells may be able metabolize intracellularly. Therefore, there a possibility that intracrine implicated ADT, influence on yet elucidated. In present...
Both Leydig cell tumor (LCT), which is a sex cord-stromal tumor, and spermatocytic (ST), germ are rare testicular tumors. Synchronous LCT ST in the unilateral testis extremely because of their different origins. Herein, we report case an 84-year-old male patient with right scrotal swelling due to tumor. His age was out onset peak but within ST. To best our knowledge, this first synchronous testis.
Neuroendocrine prostate cancer has a poor prognosis. Although disseminated intravascular coagulation associated with malignancy can be lethal, it very rarely occurs among patients primary neuroendocrine cancer.
Liposarcoma is a malignant neoplasm of the adipose tissue, and dedifferentiated liposarcoma relatively rare subtype. Liposarcomas are typically located in lower extremities or retroperitoneum, but spermatic cord no case it with macroscopic ossification has been reported literature.A male presented to our hospital painful, palpable, hard left suprapubic mass, formed over 3 months. The mass was diagnosed as tumor resected using high orchiectomy. Due histological diagnosis positive margins,...