A5103127192- Parasite Biology and Host Interactions
- Invertebrate Immune Response Mechanisms
- Evolution and Paleontology Studies
- Crustacean biology and ecology
- Migration, Aging, and Tourism Studies
- Coral and Marine Ecosystems Studies
- Marine Bivalve and Aquaculture Studies
- Insect symbiosis and bacterial influences
- Aquatic Invertebrate Ecology and Behavior
- Forensic and Genetic Research
- Sodium Intake and Health
- Gestational Diabetes Research and Management
- Vibrio bacteria research studies
- Genetic diversity and population structure
- Nutritional Studies and Diet
- Genomics and Phylogenetic Studies
- Pleistocene-Era Hominins and Archaeology
- Paleontology and Evolutionary Biology
- Phagocytosis and Immune Regulation
- Korean Urban and Social Studies
- Lymphoma Diagnosis and Treatment
- Pacific and Southeast Asian Studies
- Intergenerational Family Dynamics and Caregiving
- Studies on Chitinases and Chitosanases
- Nematode management and characterization studies
Meharry Medical College
2024
Swansea University
2018-2022
Barwon Health
2019
University of Copenhagen
2016-2019
Natural History Museum Aarhus
2016-2019
Bangor University
2016-2019
Natural History Museum of Denmark
2017
Deakin University
2013
King's College London
1988-2012
Proteins persist longer in the fossil record than DNA, but longevity, survival mechanisms and substrates remain contested. Here, we demonstrate role of mineral binding preserving protein sequence ostrich (Struthionidae) eggshell, including from palaeontological sites Laetoli (3.8 Ma) Olduvai Gorge (1.3 Tanzania. By tracking diagenesis back time find consistent patterns preservation, demonstrating authenticity surviving sequences. Molecular dynamics simulations struthiocalcin-1 -2, dominant...
Background: People of Bangladeshi origin have the highest mortality ratio from coronary heart disease any minority ethnic group in UK and their rate kidney is three- to five-fold higher than that European population. However, there little information regarding dietary customs or knowledge, beliefs attitudes towards health nutrition. This multi-method qualitative study aimed identify: (i) barriers facilitators sodium restriction; (ii) traditional current diet UK; (iii) development...
Social interaction and participation in leisure activities are positively related to the health well-being of elderly people. The main focus this exploratory study was investigate peoples' perceptions experiences social living a residential aged care (RAC) facility. Six residents were interviewed. Themes emerging from discussions about their interactions included: importance family, fostering friendships with fellow residents, placement at dining room tables, multiple communication methods,...
The parasitic dinoflagellates of the genus Hematodinium represent causative agent so-called bitter or pink crab disease in a broad range shellfish taxa. Outbreaks Hematodinium-associated can devastate local fishing and aquaculture efforts. goal our study was to examine potential role common shore (green) Carcinus maenas as reservoir for Hematodinium. is native all shores UK Ireland North East Atlantic but has been introduced to, subsequently invaded waters of, USA, South Africa Australia....
The great auk was once abundant and distributed across the North Atlantic. It is now extinct, having been heavily exploited for its eggs, meat, feathers. We investigated impact of human hunting on demise by integrating genetic data, GPS-based ocean current analyses population viability. sequenced complete mitochondrial genomes 41 individuals from species' geographic range reconstructed structure dynamics throughout Holocene. Taken together, our data do not provide any evidence that auks were...
Host, pathogen, and environment are determinants of the disease triangle, latter being a key driver outcomes persistence within community. The dinoflagellate genus Hematodinium is detrimental to crustaceans globally - considered suppress innate defences hosts, making them more susceptible co-infections. Evidence supporting immune suppression largely anecdotal sourced from diffuse accounts compromised decapods. We used population shore crabs (Carcinus maenas), where sp. endemic, determine...
Abstract This study provides a morphological and phylogenetic characterization of two novel species the order Haplosporida ( Haplosporidium carcini n. sp., H. cranc sp.) infecting common shore crab Carcinus maenas collected at one location in Swansea Bay, South Wales, UK. Both parasites were observed haemolymph, gills hepatopancreas. The prevalence clinical infections (i.e. seen directly fresh haemolymph preparations) was low, ~1%, whereas subclinical levels, detected by polymerase chain...
One hundred and seventy-three years ago, the last two Great Auks, Pinguinus impennis, ever reliably seen were killed. Their internal organs can be found in collections of Natural History Museum Denmark, but location their skins has remained a mystery. In 1999, Auk expert Errol Fuller proposed list five potential candidate museums around world. Here we take palaeogenomic approach to test which—if any—of Fuller’s likely belong either birds. Using mitochondrial genomes from birds (housed...
There is a paucity of knowledge regarding the diversity and impact(s) disease-causing fungi in marine animals, especially shellfish. In efforts to address this gap for shore crab Carcinus maenas, year-long disease screen was carried out across two sites Swansea Bay (Wales, UK) with view characterising putative fungal infections. Crabs were sampled between November 2017 October 2018, screened systematically signatures using haemolymph (blood) preparations, targeted PCR tissue histopathology....
Abstract Background Effective nutrition health interventions are theory‐based, as well being drawn from practice and research, aiming to successfully accomplish dietary behavioural changes. However, the integration of theory, research develop community educational programmes is a challenge that many interventionists feel ill equipped achieve. Methods In present study, community‐based education programme was designed for Bangladeshi patients with chronic kidney disease hypertension. The goal...
Abstract Invasion and spread of alien species can drive ecosystem changes, such as, the dynamics infectious diseases. The non-native, marine gastropod Crepidula fornicata has become established across European coastlines over last century, but there remains little insight into its disease carrying capacity potential role as a source/sink parasites. To address this knowledge gap, we surveyed limpets from two sites in South Wales, UK for signatures disease/pathology using polymerase chain...
Abstract A large knowledge gap exists regarding the disease profile and pathologic condition of invasive, slipper limpet Crepidula fornicata . To help address this, we performed a year-long health survey at two sites in South Wales, UK – subtidal Swansea Bay intertidal Milford Haven. In total, 1,800 limpets were screened systematically for haemolymph bacterial burdens using both general vibrio-selective growth media (TSA + 2% NaCl TCBS, respectively), (blood) inspection microscopy, PCR-based...
G-protein coupled receptors inhibit Cav2.2 N-type Ca2+ channels by a fast, voltage-dependent pathway mediated Gai/Gbg and slow, voltage-independent Gaq-dependent reductions in phosphatidylinositol 4,5-bisphosphate (PIP2) or increases arachidonic acid. Studies of these forms regulation generally employ Ba2+ as the permeant ion, despite that Ca2+-dependent pathways may impinge upon modulation. To address this possibility, we compared tonic inhibition currents carried (IBa) (ICa) HEK293T cells...
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Abstract Host, pathogen, and environment are determinants of the disease triangle, latter being a key driver outcomes persistence within community. The dinoflagellate genus Hematodinium is detrimental to crustaceans globally – considered suppress innate defences hosts, making them more susceptible co-infections. Evidence supporting immune-suppression largely anecdotal sourced from diffuse accounts compromised decapods. We used population shore crabs ( Carcinus maenas ), where sp. endemic,...