Matthew J. Collins
- Forensic Anthropology and Bioarchaeology Studies
- Archaeology and ancient environmental studies
- Forensic and Genetic Research
- Pleistocene-Era Hominins and Archaeology
- Identification and Quantification in Food
- Isotope Analysis in Ecology
- Cultural Heritage Materials Analysis
- Paleopathology and ancient diseases
- Collagen: Extraction and Characterization
- Enzyme Structure and Function
- Geology and Paleoclimatology Research
- Environmental DNA in Biodiversity Studies
- Pacific and Southeast Asian Studies
- Bone and Dental Protein Studies
- Genomics and Phylogenetic Studies
- Evolution and Paleontology Studies
- Molecular Biology Techniques and Applications
- Advanced Proteomics Techniques and Applications
- Image Processing and 3D Reconstruction
- Meat and Animal Product Quality
- Wildlife Ecology and Conservation
- Genetic diversity and population structure
- Calcium Carbonate Crystallization and Inhibition
- Oral microbiology and periodontitis research
- Microbial Community Ecology and Physiology
Evolutionary Genomics (United States)
2022-2025
University of Copenhagen
2007-2025
Arthur B. McDonald-Canadian Astroparticle Physics Research Institute
2022-2025
University of Cambridge
2018-2025
Globe University
2025
Jefferson Hospital
2024
University of York
2013-2023
Natural History Museum Aarhus
2017-2023
Duke University
2002-2023
Globe Institute of Technology
2023
Claims of extreme survival DNA have emphasized the need for reliable models degradation through time. By analysing mitochondrial (mtDNA) from 158 radiocarbon-dated bones extinct New Zealand moa, we confirm empirically a long-hypothesized exponential decay relationship. The average half-life within this geographically constrained fossil assemblage was estimated to be 521 years 242 bp mtDNA sequence, corresponding per nucleotide fragmentation rate (k) 5.50 × 10(-6) year. With an effective...
Species identification of fragmentary bone, such as in rendered meat and bone meal or from archaeological sites, is often difficult the absence clear morphological markers. Here we present a robust method analysing genus-specific collagen peptides by mass spectrometry simply using solid-phase extraction (a C18 ZipTip) for peptide purification, rather than liquid chromatography/mass (LC/MS). Analysis 32 different mammal species identified total 92 markers that could be used identification,...
It is difficult to obtain fossil data from the 10% of Earth's terrestrial surface that covered by thick glaciers and ice sheets, hence, knowledge paleoenvironments these regions has remained limited. We show DNA amino acids buried organisms can be recovered basal sections deep cores, enabling reconstructions past flora fauna. high-altitude southern Greenland, currently lying below more than 2 kilometers ice, was inhabited a diverse array conifer trees insects within million years. The...
Significance The displacement of Neandertals by anatomically modern humans (AMHs) 50,000–40,000 y ago in Europe has considerable biological and behavioral implications. Châtelperronian at the Grotte du Renne (France) takes a central role models explaining transition, but association hominin fossils this site with is debated. Here we identify additional specimens through proteomic zooarchaeology mass spectrometry screening obtain molecular (ancient DNA, ancient proteins) chronometric data to...
Proteins persist longer in the fossil record than DNA, but longevity, survival mechanisms and substrates remain contested. Here, we demonstrate role of mineral binding preserving protein sequence ostrich (Struthionidae) eggshell, including from palaeontological sites Laetoli (3.8 Ma) Olduvai Gorge (1.3 Tanzania. By tracking diagenesis back time find consistent patterns preservation, demonstrating authenticity surviving sequences. Molecular dynamics simulations struthiocalcin-1 -2, dominant...
Abstract Milk is a major food of global economic importance and its consumption regarded as classic example gene-culture evolution. Humans have exploited animal milk resource for at least 8500 years, but the origins, spread scale dairying remain poorly understood. Indirect lines evidence, such lipid isotopic ratios pottery residues, faunal mortality profiles lactase persistence allele frequencies, provide partial picture this process; however, in order to understand how, where when humans...
Late Pliocene and Early Pleistocene epochs 3.6 to 0.8 million years ago
How humans got their goats Little is known regarding the location and mode of early domestication animals such as for husbandry. To investigate history goat, Daly et al. sequenced mitochondrial nuclear sequences from ancient specimens ranging hundreds to thousands years in age. Multiple wild populations contributed origin modern during Neolithic. Over time, one type spread became dominant worldwide. However, at whole-genome level, goat are a mix different sources provide evidence multilocus...
How cow genomes have moo-ved Cattle were domesticated ∼10,000 years ago, but analysis of modern breeds has not elucidated their origins. Verdugo et al. performed genome-wide 67 ancient Near Eastern Bos taurus DNA samples. Several populations aurochs progenitors domestic cows. These genetic lineages mixed ∼4000 ago in a region around the Indus Valley. Interestingly, mitochondrial indicated that material likely derived from arid-adapted indicus (zebu) bulls was introduced by introgression....
The origins and prehistory of domestic sheep (Ovis aries) are incompletely understood; to address this, we generated data from 118 ancient genomes spanning 12,000 years sampled across Eurasia. Genomes Central Türkiye ~8000 BCE genetically proximal the but do not fully explain ancestry later populations, suggesting a mosaic wild ancestries. Genomic signatures indicate selection by herders for pigmentation patterns, hornedness, growth rate. Although first European flocks derive Türkiye, in...