Amelie Scheu
A5082220302- Forensic and Genetic Research
- Genetic and phenotypic traits in livestock
- Genetic diversity and population structure
- Archaeology and ancient environmental studies
- Forensic Anthropology and Bioarchaeology Studies
- Identification and Quantification in Food
- Paleopathology and ancient diseases
- Genomics and Phylogenetic Studies
- Animal Diversity and Health Studies
- Rabies epidemiology and control
- Wildlife Ecology and Conservation
- Human-Animal Interaction Studies
- Genetic Mapping and Diversity in Plants and Animals
- Digestive system and related health
- Pleistocene-Era Hominins and Archaeology
- Rangeland Management and Livestock Ecology
- Pacific and Southeast Asian Studies
- Environmental DNA in Biodiversity Studies
- Meat and Animal Product Quality
- Molecular Biology Techniques and Applications
- Innovation, Technology, and Society
- Nutrition, Genetics, and Disease
- Digital Transformation in Industry
- Cancer-related molecular mechanisms research
- Ancient and Medieval Archaeology Studies
Johannes Gutenberg University Mainz
2007-2025
Trinity College Dublin
2015-2024
Neu-Ulm University of Applied Sciences
2022
Deutsches Archäologisches Institut, Zentrale
2007-2015
Deutsches Archäologisches Institut, Eurasien-Abteilung
2007
Farming and sedentism first appeared in southwestern Asia during the early Holocene later spread to neighboring regions, including Europe, along multiple dispersal routes. Conspicuous uncertainties remain about relative roles of migration, cultural diffusion, admixture with local foragers Neolithization Europe. Here we present paleogenomic data for five Neolithic individuals from northern Greece northwestern Turkey spanning time region earliest farming into We use a novel approach...
Near Eastern genomes from Iran The genetic composition of populations in Europe changed during the Neolithic transition hunting and gathering to farming. To better understand origin modern populations, Broushaki et al. sequenced ancient DNA four individuals Zagros region present-day Iran, representing early Fertile Crescent. These unexpectedly were not ancestral European farmers, their structures did contribute significantly those Europeans. data indicate that a parallel probably resulted...
Horse domestication revolutionized warfare and accelerated travel, trade, the geographic expansion of languages. Here, we present largest DNA time series for a non-human organism to date, including genome-scale data from 149 ancient animals 129 genomes (≥1-fold coverage), 87 which are new. This extensive dataset allows us assess modern legacy past equestrian civilizations. We find that two extinct horse lineages existed during early domestication, one at far western (Iberia) other eastern...
Abstract Europe has played a major role in dog evolution, harbouring the oldest uncontested Palaeolithic remains and having been centre of modern breed creation. Here we sequence genomes an Early End Neolithic from Germany, including sample associated with early European farming community. Both dogs demonstrate continuity each other predominantly share ancestry dogs, contradicting previously suggested Late population replacement. We find no genetic evidence to support recent hypothesis...
How humans got their goats Little is known regarding the location and mode of early domestication animals such as for husbandry. To investigate history goat, Daly et al. sequenced mitochondrial nuclear sequences from ancient specimens ranging hundreds to thousands years in age. Multiple wild populations contributed origin modern during Neolithic. Over time, one type spread became dominant worldwide. However, at whole-genome level, goat are a mix different sources provide evidence multilocus...
How cow genomes have moo-ved Cattle were domesticated ∼10,000 years ago, but analysis of modern breeds has not elucidated their origins. Verdugo et al. performed genome-wide 67 ancient Near Eastern Bos taurus DNA samples. Several populations aurochs progenitors domestic cows. These genetic lineages mixed ∼4000 ago in a region around the Indus Valley. Interestingly, mitochondrial indicated that material likely derived from arid-adapted indicus (zebu) bulls was introduced by introgression....
The origins and prehistory of domestic sheep (Ovis aries) are incompletely understood; to address this, we generated data from 118 ancient genomes spanning 12,000 years sampled across Eurasia. Genomes Central Türkiye ~8000 BCE genetically proximal the but do not fully explain ancestry later populations, suggesting a mosaic wild ancestries. Genomic signatures indicate selection by herders for pigmentation patterns, hornedness, growth rate. Although first European flocks derive Türkiye, in...
The extinct aurochs ( Bos primigenius ) was a large type of cattle that ranged over almost the whole Eurasian continent. is wild progenitor modern cattle, but it unclear whether European contributed to this process. To provide new insights into demographic history and domestic we have generated high-confidence mitochondrial DNA sequences from 59 archaeological skeletal finds, which were attributed populations based on their chronological date and/or morphology. All pre-Neolithic belonged...
Archaeological evidence indicates that pig domestication had begun by ∼10,500 y before the present (BP) in Near East, and mitochondrial DNA (mtDNA) suggests pigs arrived Europe alongside farmers ∼8,500 BP. A few thousand years after introduction of Eastern into Europe, however, their characteristic mtDNA signature disappeared was replaced haplotypes associated with European wild boars. This turnover could be accounted for substantial gene flow from local boars, although it is also possible...
Abstract Summary Post-mortem damage (PMD) obstructs the proper analysis of ancient DNA samples and can currently only be addressed by removing or down-weighting potentially damaged data. Here we present ATLAS, a suite methods to accurately genotype estimate genetic diversity from samples, while accounting for PMD. It works directly raw BAM files enables building complete customized pipelines other low-depth in very user-friendly way. Based on simulations show that, presence PMD, dedicated...
Abstract The two living species of bison (European and American) are among the few terrestrial megafauna to have survived late Pleistocene extinctions. Despite extensive bovid fossil record in Eurasia, evolutionary history European (or wisent, Bison bonasus ) before Holocene (<11.7 thousand years ago (kya)) remains a mystery. We use complete ancient mitochondrial genomes genome-wide nuclear DNA surveys reveal that wisent is product hybridization between extinct steppe ( priscus ancestors...
High-throughput sequencing has dramatically fostered ancient DNA research in recent years. Shotgun sequencing, however, does not necessarily appear as the best-suited approach due to extensive contamination of samples with exogenous environmental microbial DNA. capture-enrichment methods represent cost-effective alternatives that increase focus on endogenous fraction, whether it is from mitochondrial or nuclear genomes, parts thereof. Here, we explored experimental parameters could impact...
The recovery and analysis of ancient DNA protein from archaeological bone is time-consuming expensive to carry out, while it involves the partial or complete destruction valuable rare specimens. fields palaeogenetic palaeoproteomic research would benefit greatly techniques that can assess molecular quality prior sampling. To be relevant, such screening methods should effective, minimally-destructive, rapid. This study reports results based on spectroscopic (Fourier-transform infrared...
Abstract Ancient genomic analyses are often restricted to utilizing pseudohaploid data due low genome coverage. Leveraging low-coverage by imputation calculate phased diploid genotypes that enables haplotype-based interrogation and single nucleotide polymorphism (SNP) calling at unsequenced positions is highly desirable. This has not been investigated for ancient cattle genomes despite these being compelling subjects archeological, evolutionary, economic reasons. Here, we test this approach...
Abstract Farming and sedentism first appear in southwest Asia during the early Holocene later spread to neighboring regions, including Europe, along multiple dispersal routes. Conspicuous uncertainties remain about relative roles of migration, cultural diffusion admixture with local foragers Neolithisation Europe. Here we present paleogenomic data for five Neolithic individuals from northwestern Turkey northern Greece – spanning time region earliest farming into We observe striking genetic...
Abstract Ancient genomic analyses are often restricted to utilising pseudo-haploid data due low genome coverage. Leveraging coverage by imputation calculate phased diploid genotypes that enable haplotype-based interrogation and SNP calling at unsequenced positions is highly desirable. This has not been investigated for ancient cattle genomes despite these being compelling subjects archaeological, evolutionary economic reasons. Here we test this approach sequencing a Mesolithic European...
Abstract Europe has played a major role in dog evolution, harbouring the oldest uncontested Paleolithic remains and having been centre of modern breed creation. We sequenced whole genomes an Early End Neolithic from Germany, including sample associated with one Europe’s earliest farming communities. Both dogs demonstrate continuity each other predominantly share ancestry European dogs, contradicting previously suggested Late population replacement. Furthermore, we find no genetic evidence to...