A5061891377- Hematopoietic Stem Cell Transplantation
- Renal Transplantation Outcomes and Treatments
- T-cell and B-cell Immunology
- Pharmacovigilance and Adverse Drug Reactions
- Rheumatoid Arthritis Research and Therapies
- Heavy Metal Exposure and Toxicity
- Curcumin's Biomedical Applications
- Academic integrity and plagiarism
- Pharmaceutical Practices and Patient Outcomes
- Methemoglobinemia and Tumor Lysis Syndrome
- Cytokine Signaling Pathways and Interactions
- Dental Health and Care Utilization
- Oral microbiology and periodontitis research
- Dental Research and COVID-19
- Infrared Thermography in Medicine
- Erythrocyte Function and Pathophysiology
- Polyomavirus and related diseases
- interferon and immune responses
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Tryptophan and brain disorders
- Monoclonal and Polyclonal Antibodies Research
- Spondyloarthritis Studies and Treatments
- Renal Diseases and Glomerulopathies
- Computational Drug Discovery Methods
- Cytomegalovirus and herpesvirus research
Riyadh Elm University
2016-2023
Jackson Laboratory
2006-2007
Journal Article Enhanced half-life of genetically engineered human IgG1 antibodies in a humanized FcRn mouse model: potential application humorally mediated autoimmune disease Get access Stefka B. Petkova, Petkova 1Jackson Laboratory, Bar Harbor, ME 04609, USA Search for other works by this author on: Oxford Academic PubMed Google Scholar Shreeram Akilesh, Akilesh USA4Present address: Department Pathology, Washington University, St Louis, MO, Thomas J. Sproule, Sproule Gregory Christianson,...
Cadmium, a ubiquitous environmental toxicant, disrupts testicular function and fertility. The dipeptidyl peptidase-4 inhibitor linagliptin has shown pronounced anti-inflammatory anti-apoptotic features; however, its effects against cadmium-evoked impairment have not been examined. Herein, the present study investigated targeting inflammation, apoptosis, autophagy by for potential modulation of cadmium-induced dysfunction in rats. After 60 days cadmium chloride administration (5 mg/kg/day,...
Colitis is one of the inflammatory states that affect intestinal wall and may even predispose to malignancy due chronic irritation. Although etiology colitis not yet fully explored, a combination genetic environmental factors strongly incriminated. Perindopril an angiotensin-converting enzyme inhibitor used for management wide range cardiovascular diseases. Ambrosin sesquiterpene lactone was proven have beneficial effects in disorders characterized by nature. The objective this study make...
To study the impact of examination stress on total antioxidant capacity (TAC) senior dental students and compare changes in TAC between who exercise regularly those do not.A questionnaire designed to evaluate physical activity levels, body mass index (BMI) academic performance was distributed 325 students. Of 312 responded, a 70 were enrolled study, whom 60 completed study. The composed low-activity group (n = 30), had Goddard-Sheppard (GS) score <25, high-exercise GS >60. Dental Environment...
The success of orthotopic liver transplantation as a life-saving treatment has led to new indications and greater competition for organ grafts. Pediatric patients with acute liver-related crises can benefit from transplantation, but availability in the limited time be major obstacle. Crossing ABO blood group barriers could increase organs available such patients.From November 2010 June 2015, 176 children aged 0.2-to18 y were transplanted King Faisal Specialist Hospital Research Center. Out...
Abstract Background: primary graft failure is a devastating complication after allogeneic transplant. Donor specific antibodies has been reported as major risk factor contributing to failure. We retrospectively analyzed our haploidentical transplant registry report the incidence and impact of DSA anti-HLA on engraftment in cohort malignant hematologic disease conditioned with myeloablative regimens. Methods: retrospective analysis consecutive cases disorders who received haplo-HSCT at single...
Aim: Drug Ineffective (DI) reports are Adverse Events (ADE) important for post-marketing surveillance (PMS). Currently drug safety information from the DI received by Saudi Food and Authority (SFDA) via Vigilance System (SVS) is undetermined. The study aims to describe SVS different stakeholders.
 Methods: between January 2020 December 2021 were retrieved characterized based on patients’ demographics, reporter type suspected group in comparison non-DI reports. Potential determinants of...
Abstract Studies both in mice and humans have argued that immunodominant MHAg eliciting CD8 T cells cause increased risk for GVHD. We shown the H60 is remarkably an overwhelmingly predominant cell response developed after transfer of bone marrow (BM) into MHAg-mismatched lethally irradiated recipients directed against H60. Here we address whether a barrier to lethal (L) Matching donor while remaining disparate all other failed result improved survival, indicating not LGVHD. Expression...
Glucose-6-phosphate dehydrogenase (G6PD) is an enzyme responsible for the production of NADPH pathway. Mutation in G6PD gene results abnormal functional and structural changes red blood cells (RBCs). The aim current study to compare levels apoptosis Saudi people suffering from deficiency. Twenty samples unrelated children neonates between ages 1 month 10 years were collected. Ten ml Blood collected by venipuncture EDTA tubes, hematological parameters assessed using Coulter Counter Analyzer....