A5002643397- Sustainable Supply Chain Management
- Complex Network Analysis Techniques
- Supply Chain Resilience and Risk Management
- Transportation Planning and Optimization
- Supply Chain and Inventory Management
- Facility Location and Emergency Management
- Alzheimer's disease research and treatments
- Dementia and Cognitive Impairment Research
- Infrastructure Resilience and Vulnerability Analysis
- Complex Systems and Time Series Analysis
- Opinion Dynamics and Social Influence
- Recycling and Waste Management Techniques
- Formal Methods in Verification
- Muscle Physiology and Disorders
- Network Traffic and Congestion Control
- Genetic Neurodegenerative Diseases
- VLSI and Analog Circuit Testing
- Network Security and Intrusion Detection
- Game Theory and Applications
- 14-3-3 protein interactions
- Economic theories and models
- Environmental Sustainability in Business
- Software Testing and Debugging Techniques
- Parkinson's Disease Mechanisms and Treatments
- Urban Transport and Accessibility
Huadong Hospital
2015-2025
Fudan University
2014-2025
University of Occupational and Environmental Health Japan
2022-2025
Changzhou No.2 People's Hospital
2023-2024
Pennsylvania State University
2009-2022
Tsinghua University
2022
Pepperdine University
2022
Great Valley Center
2007-2021
Taiyuan University of Technology
2019
University of Massachusetts Amherst
2007-2019
In this paper, we propose a network efficiency measure for congested networks, that captures demands, costs, flows, and behavior. The efficiency/performance can identify which components, is, nodes links, have the greatest impact in terms of their removal, due to, example, natural disasters, structural failures, terrorist attacks, etc., and, hence, are important from both vulnerability as well security standpoints. new is applied to Braess paradox demands varied over horizon explicit...
Abstract This paper provides an overview of some the recent developments in assessment network vulnerability and robustness through appropriate tools that assist quantification efficiency/performance identification importance components, such as nodes links. We demonstrated how rigorously constructed well‐defined measures can capture not only topology underlying a particular critical system, but also behavior decision‐makers, resulting flows, induced costs reality demands for resources,...
ABSTRACT This paper proposes environmental impact assessment indices to evaluate the effects of link capacity degradation in transportation (road) networks. The are applicable case either user-optimizing or system-optimizing behavior. We also construct importance indicators that allow for ranking links networks terms their importance, should they be removed/destroyed. Numerical network examples illustrate proposed quantitative and further substantiate behavior does not necessarily lead...
In this paper we consider the design of supply chain networks in case critical needs as may occur, for example, disasters, emergencies, pending epidemics, and attacks affecting national security. By 'critical needs' mean products that are essential to survival population, which can include, vaccines, medicine, food, water, etc., depending upon particular application. 'Critical' implies demand product should be met nearly possible since otherwise there additional loss life. The model develop...
Polyglutamine (polyQ) diseases are inherited neurodegenerative disorders that caused by the expansion of trinucleotide CAG repeats in causative genes. Spinal and bulbar muscular atrophy (SBMA) is an motor neuron disease a polyQ tract within androgen receptor (AR). p62 ubiquitin- light-chain 3-binding protein known to regulate degradation targeted proteins via autophagy inclusion formation. In this study, we examined effects depletion overexpression on cultured cells transgenic mouse model...
To test whether cerebrospinal fluid (CSF) growth-associated protein 43 (GAP-43) concentration is elevated in Alzheimer's disease (AD) dementia and its associations with other hallmarks of AD, we examined the CSF GAP-43 measurements 787 participants (245 cognitively normal (CN), 415 individuals mild cognitive impairment (MCI) 127 AD dementia) from Disease Neuroimaging Initiative (ADNI) study. Associations were investigated between clinical diagnosis, Aβ/tau/neurodegeneration (AT(N)) status,...
In this study, we investigated the antioxidant properties of dry-cured beef crude peptide (BPH) at different storage periods. The combination characteristics concentrations Phe-Asp-Gly-Asp-Phe (FDGDF) and superoxide dismutase (SOD) temperatures were analyzed by ultraviolet–visible spectroscopy, fluorescence FT-IR combined with detection a SOD activity box. It was found that FDGDF could improve changing its secondary structure. Bonds formed O32/O40/O52 using quantum chemical simulation...
Atypical teratoid/rhabdoid tumor (AT/RT) is a kind of central nervous system malignant in children. In this study, we aimed to develop practically clinical nomogram and risk grouping predict 1-year overall survival for patients with atypical tumor. The was constructed based on the pediatric registry Xinhua Hospital affiliated Shanghai Jiaotong University School Medicine. Fifty-four information-integrated were included from database. Cox regression analyses used select independent prognostic...
In this paper, we demonstrate how to capture the robustness of a transportation network in case degradable links represented by decreasing capacities. The analysis is conducted utilizing Bureau Public Road link travel cost functions and recently proposed efficiency measure for congested networks. For specific networks are able derive lower bounds when percentage reductions capacities take place.
The accumulation of abnormal proteins is a common characteristic neurodegenerative diseases. This reflects severe disturbance cellular homeostasis in pathogenic protein clearance. Here, we demonstrated that the activation two major proteolytic machineries, molecular chaperone–ubiquitin proteasome system (UPS) and autophagy system, were simultaneously enhanced by paeoniflorin (PF), component Paeonia plants, exerted therapeutic effects models spinal bulbar muscular atrophy (SBMA). PF...
A cross-sectional study was conducted to evaluate patterns of gray matter changes in cognitively normal elderly adults with mild behavioral impairment (MBI).Sixteen MBI patients and 18 healthy controls were selected.All the participants underwent a neuropsychological assessment battery, including Mini-mental State Examination (MMSE), Geriatric Depression Scale (GDS), Self-rating Anxiety (SAS), Chinese version impairment-checklist scale (MBI-C), magnetic resonance imaging (MRI) scans.Imaging...
Due to the increasing awareness of sustainable manufacturing, remanufacturing has been widely accepted by enterprises in many countries. In process Closed-Loop Supply Chain (CLSC) development, stimulate demand for remanufactured products, Chinese government’s interventions such as “Trade old Remanufactured” program cannot be ignored. However, prior research not answered questions whether governments should offer consumption subsidies and how determine optimal subsidy value. This paper...
In this paper, we propose a transportation network efficiency measure that can be used to assess the performance of and which differs from other proposed measures, including complex in it captures flows, costs, travel behavior information, along with topology. The new allows one determine criticality various nodes (as well as links) demonstrate through component importance definition, is well-defined even if becomes disconnected. Several illustrative examples are provided efficiencies...
Abstract In this paper, we demonstrate how to capture the robustness of a transportation network in case degradable links represented by decreasing capacities. particular, with use Bureau Public Roads user link travel cost functions, propose two relative total indices assess behavior associated either optimization or system optimization. We derive upper bounds index for networks special structure and congestion parameters under optimal flow pattern. also an bound pattern general networks....