A5046074448- Diet, Metabolism, and Disease
- Liver Disease Diagnosis and Treatment
- Nutritional Studies and Diet
- Vitamin D Research Studies
- Obesity, Physical Activity, Diet
- Dietary Effects on Health
- Natural Antidiabetic Agents Studies
- Diet and metabolism studies
- Ginseng Biological Effects and Applications
- Adipokines, Inflammation, and Metabolic Diseases
- Health disparities and outcomes
- Health and Well-being Studies
- Tea Polyphenols and Effects
- Hemoglobinopathies and Related Disorders
- Gut microbiota and health
- Cardiovascular Health and Risk Factors
- Muscle metabolism and nutrition
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Nutrition, Genetics, and Disease
- Cardiovascular Disease and Adiposity
- Adipose Tissue and Metabolism
- Epigenetics and DNA Methylation
- Vitamin C and Antioxidants Research
- Antioxidant Activity and Oxidative Stress
- Nanoparticle-Based Drug Delivery
Ahvaz Jundishapur University of Medical Sciences
2015-2024
Tabriz University of Medical Sciences
2022-2024
Kashan University of Medical Sciences
2023
Islamic Azad University, Ahvaz Branch
2021
Golestan University of Medical Sciences
2018-2021
Brunel University of London
2021
Golestan University
2018-2019
Shahid Beheshti University
2017
Unité de recherche sur les maladies cardiovasculaires et métaboliques
2014
The systemic administration of cytotoxic chemotherapeutic agents for cancer treatment often has toxic side effects, limiting the usage dose. To increase efficacy while reducing a rational design synergy-based drug regimens is essential. This study investigated augmentation therapeutic effectiveness with co-administration paclitaxel (PTX; an effective breast cancer) and curcumin (CUR; chemosensitizer) in MCF-7 cell line.We optimized niosome formulations terms surfactant cholesterol content....
Background. Chronic kidney disease (CKD) is a covert disease. Accurate prediction of CKD progression over time necessary for reducing its costs and mortality rates. The present study proposes an adaptive neurofuzzy inference system (ANFIS) predicting the renal failure timeframe based on real clinical data. Methods. This used 10-year records newly diagnosed patients. threshold value 15 cc/kg/min/1.73 m 2 glomerular filtration rate (GFR) was as marker failure. A Takagi-Sugeno type ANFIS model...
This trial aimed to investigate the effects of rutin supplement in type 2 diabetes mellitus (T2DM) patients.In this with a double-blind and controlled design, fifty patients were randomly divided into intervention (n = 25) control groups treated 1 g or placebo for three months, respectively. At baseline end intervention, mean arterial pressure (MAP), heart rate (HR), pulse (PP), systolic diastolic blood (SBP DBP), serum levels antioxidant enzymes, such as catalase (CAT), glutathione...
Based on research findings around the globe, content of heavy metals (HM) has been kept limited in traditional popular pastries. This study was carried out to conduct a health risk assessment (As, Cd, Cu, Ni, Pb, Sn, and Zn) Qom's Sohan (a kind Persian saffron brittle toffee) 2015. Samples were selected randomly from most brands workshops Qom. After dry digestion all samples, 100 different analyzed via inductively coupled plasma atomic emission spectroscopy (ICP-AES). In this study, about...
Abstract Aim N‐acetylcysteine (NAC), a thiol‐containing antioxidant and glutathione (GSH) precursor, attenuates oxidative stress, possibly improves psychiatric disorders. This study aimed to evaluate the effects of oral NAC on depression, anxiety symptoms in patients with multiple sclerosis (MS). Methods clinical trial was conducted 42 MS randomly assigned intervention ( n = 21) control groups. The group received 600 mg twice daily for 8 weeks, placebo same prescription form. An analysis...
The prevalence of kidney stones is on the rise globally. Several risk factors, including lifestyle, contribute to formation stones. Nevertheless, there a contentious debate about relationship between diet and Therefore, our study aimed assess macronutrients micronutrients
Asthma is a heterogeneous disease which usually associated with chronic airway inflammation. Saffron has anti-inflammatory effects and may beneficial on asthma. The present study was intended to survey the of saffron supplementation blood pressure, lipid profiles, basophils, eosinophils clinical symptoms in patients allergic Our trial. Subjects (N = 80, 32 women 48 men, 41.25 ± 9.87 years old) mild moderate asthma were randomized into two groups: intervention group who received capsules (100...
Background: Mental disorders is one of the main causes disability and lower life expectancy among patients with Multiple Sclerosis (MS). The present trial aimed to examine efficacy multi-strain probiotic supplementation on circulating levels BDNF, NGF, IL-6 mental health in MS.Methods: This was conducted 70 MS that referred Association. Patients were randomized into intervention control groups receive 2 capsules or placebo, daily for six months. Serum NGF measured by ELISA kits. parameters...
Abstract Background Research on Metabolic Associated Fatty Liver Disease (MAFLD) is still in its early stages, with few studies available to identify and predict effective indicators of this disease. On the other hand, diagnosis intervention are crucial reduce burden MAFLD. Therefore, aim research was investigate effectiveness eleven anthropometric indices their appropriate cut-off values as a non-invasive method diagnose MAFLD Iranian population. Methods In cross-sectional study, we...
Abstract A two-arm randomized open labeled controlled clinical trial was conducted on 50 patients with non-alcoholic fatty liver disease (NAFLD). Subjects were to either receive two tablets of soy isoflavone (100 mg/day) or placebo. At week 12, the serum levels alanine amino transferase (ALT), aspartate (AST) and attenuation parameter (CAP) score significantly decreased only in group (P < 0.05). significant decline gamma glutamyl (GGT) level observed placebo = 0.017). increase fetuin...
Abstract Background Non-alcoholic fatty liver disease (NAFLD) accounts as a crucial health concern with huge burden on and economic systems. The aim of this study is to evaluate the effect soy isoflavones supplementation metabolic status in patients NAFLD. Methods In randomized clinical trial, 50 NAFLD were randomly allocated either isoflavone or placebo groups for 12 weeks. group took 100 mg/d similar tablets containing starch. Anthropometric indices, blood lipids, glycemic parameters...
Background: Non-alcoholic fatty liver disease (NAFLD) is a major worldwide public health problem with no effective treatment options. Green coffee bean extract (GCBE) rich source of bioactive phytochemicals variety biochemical and physiological effects. Objectives: The aim this study was to investigate the effects GCBE on management patients NAFLD. Methods: 44 NAFLD were enrolled in parallel, double-blind, placebo-controlled clinical trial. participants administered either or placebo (1...
Background and objectives: Mounting evidence shows that curcumin, a bioactive substance originating from turmeric root, has anticancer properties. Additionally, curcumin prevents the migration metastasis of tumor cells. However, molecular mechanism involved in anti-metastatic action is not clear. Most studies have suggested inhibition related to curcumin’s anti-inflammatory Curcumin possesses regulatory effect on insulin insulin-like growth factor-1 (IGF-1) receptors signaling. Insulin...
Non-alcoholic fatty liver disease (NAFLD) is one of the most common chronic disorders. The main causes NAFLD are associated with insulin resistance, severe lipid metabolism disorders, oxidative stress and inflammation. Previous studies have reported that ginger has positive metabolic results.The aim this study was to determine effect powder supplement on profiles, enzymes, inflammatory cytokines antioxidant status in patients NAFLD.In randomized clinical trial, 46 people were parted into two...
The imbalance between pro-oxidant and antioxidant systems often leads to further oxidative damage in the pathogenesis of both diabetes periodontal disease. This study aimed investigate anti-inflammatory properties melatonin type 2 mellitus (T2DM) patients with disease (PD) under non-surgical therapy (NSPT).In this double-blind clinical trial study, 50 T2DM PD were randomly allocated intervention control groups received 250 mg/day (2 tablets) either or placebo 1 h before bedtime for 8 weeks....
Background: The role of metabolic states in cardiovascular risks among individuals with varying degrees obesity is unknown. study aimed to compare cardiometabolic index (CMI), atherogenic plasma (AIP), lipid accumulation product (LAP) and novel anthropometric indices non-metabolically obese individual regard the FTO gene Iranian adults. Methods: In total, 165 were recruited into this cross-sectional study. Individuals grouped four groups: healthy normal-weight (MHNW) individuals,...
Overweight and obesity are major health concerns worldwide, with adverse consequences during the life span. This study measured socioeconomic inequality in overweight among Iranian adults.Data were extracted from 129,257 adults (aged 35 years older) participated Prospective Epidemiologic Research Studies IrAN (PERSIAN) 14 provinces of Iran 2014. Socioeconomic-related was estimated using Concentration Index (Cn). The Cn further decomposed to find factors explaining variability within...