A5081237660- Natural product bioactivities and synthesis
- Neuroscience and Neuropharmacology Research
- Neuroinflammation and Neurodegeneration Mechanisms
- Alzheimer's disease research and treatments
- Phytochemistry and Biological Activities
- Trace Elements in Health
- Curcumin's Biomedical Applications
- Stress Responses and Cortisol
- Tryptophan and brain disorders
- Inflammasome and immune disorders
- Vitamin D Research Studies
- Computational Drug Discovery Methods
- Adipose Tissue and Metabolism
- Nuclear Receptors and Signaling
- Neuroendocrine regulation and behavior
- GABA and Rice Research
- Effects and risks of endocrine disrupting chemicals
- Medicinal Plants and Bioactive Compounds
- Sesame and Sesamin Research
- Mitochondrial Function and Pathology
- Bone Metabolism and Diseases
- Neurogenesis and neuroplasticity mechanisms
- Neurological Disease Mechanisms and Treatments
- Monoclonal and Polyclonal Antibodies Research
- Ion channel regulation and function
Ahvaz Jundishapur University of Medical Sciences
2016-2024
Shahid Chamran University of Ahvaz
2015
Abstract Objective Alzheimer's disease (AD) is mainly caused by accumulation of β‐amyloid (Aβ) in vessels or parenchyma the brain. Accordingly, natural compounds such as betulinic acid (BA) might improve AD signs increase blood flow and through reduction amyloid plaques. Methods Intra‐hippocampal injection BA (0.2 0.4 μmol/L /10 μL DMSO /rat) was done at intervals 180 10 min before co‐microinjection 0.1 Aβ dissolved PBS (5 μL/rat, hippocampi) 1.5 mg/kg Streptozotocin aCSF (10 lateral...
Background: Cumulative evidence shows that dysregulation of the hypothalamic-pituitary-adrenal (HPA) axis is involved in depressive disorders and natural or synthetic glucocorticoids have a direct effect on HPA activity. Objectives: Considering reports show zinc deficiency one causes depressive-like behavior, current study aimed to examine effects systemic injection chloride (ZnCl2) and/or dexamethasone sodium-phosphate (DEX) depression adult male rats. Materials Methods: Different groups...
Seizure is a prevalent disorder reflected by powerful and sudden activity of neural networks in the brain that leads to tonic-clonic attacks. These signs may be due an increase excitatory/inhibitory neurotransmitters ratio. So, current experiment aimed examine seizure neurobehavioral parameters, as well hippocampus local electroencephalogram (EEG) after with without sesamin pretreatment.Sesamin (15, 30, 60 mg/kg/5 ml, intraperitoneal or IP, vehicle: dimethyl sulfoxide DMSO, for 3 days) was...