Hirohisa Kinoshita

ORCID: 0000-0002-9077-1612
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Research Areas
  • earthquake and tectonic studies
  • Schizophrenia research and treatment
  • Mental Health Treatment and Access
  • Trauma and Emergency Care Studies
  • Earthquake and Disaster Impact Studies
  • Posttraumatic Stress Disorder Research
  • Geophysical and Geoelectrical Methods
  • Earthquake and Tsunami Effects
  • Digital Mental Health Interventions
  • Cardiac Arrest and Resuscitation
  • Healthcare professionals’ stress and burnout
  • Impact of Technology on Adolescents
  • Tryptophan and brain disorders
  • Dementia and Cognitive Impairment Research
  • Neuroendocrine Tumor Research Advances
  • Heart Failure Treatment and Management
  • Child Development and Digital Technology
  • Landslides and related hazards
  • Health and Well-being Studies
  • Gastrointestinal Tumor Research and Treatment
  • Treatment of Major Depression
  • Obsessive-Compulsive Spectrum Disorders
  • Geomagnetism and Paleomagnetism Studies
  • Geophysics and Gravity Measurements
  • Drug-Induced Adverse Reactions

Nagasaki University
2005-2024

Nagasaki University Hospital
2010-2022

Japan Organization of Occupational Health and Safety
2020

Yokohama Rosai Hospital
2011-2020

Nagasaki Rousai Hospital
1998

Chiba University
1986-1994

Abstract Background The mode of onset and the course schizophrenia illness exhibit substantial individual variations. Previous studies have pointed out that affects duration untreated psychosis (DUP) clinical outcomes, such as cognitive social functioning. This study attempted to clarify association between DUP features, taking different modes into consideration, in a prospective longitudinal examining patients with first-episode schizophrenia. Methods was conducted six areas Japan. Patients...

10.1016/j.eurpsy.2015.08.004 article EN European Psychiatry 2015-10-24

Aim Anaphylaxis is a systemic allergic reaction that potentially causes death. Most anaphylactic reactions are uniphasic, but some cases may be biphasic or protracted. However, these clinical epidemiology concepts unfamiliar in J apan. Therefore, we have investigated the incidences and characteristics of patients with protracted anaphylaxis. Methods We retrospectively evaluated anaphylaxis single emergency medical center located Y okohama, apan from A pril 2009 to M arch 2012. analyzed who...

10.1002/ams2.48 article EN Acute Medicine & Surgery 2014-05-19

Tectonic movement may disturb lateral continuities of crustal structures at weak zones. These discontinuities density structure cause undulations the gravity anomaly field whose complexity can be an indicator past instability. On other hand, topographic lineaments are formed along We would expect therefore that roughness bears some relation to distribution surface lineaments. develop a statistical method by employing Bouguer standard deviation as index in terms which we interpret spatial...

10.1186/bf03352505 article EN cc-by Earth Planets and Space 2014-06-24

Abstract Background Patients with primary focal hyperhidrosis (hyperhidrosis) are known to have higher levels of anxiety induced by sweating than those who do not. However, in hyperhidrosis, no scale has been developed measure specific symptoms. Therefore, this study aimed develop an symptoms (ASSHS) and verify its reliability validity. Methods Based on previous studies a preliminary survey conducted 26 university students met the diagnostic criteria for 40 items that adequately reflected...

10.1186/s13030-024-00310-y article EN cc-by BioPsychoSocial Medicine 2024-06-04

鹿部冲の海底に分布する北海道駒ヶ岳火山1640年の岩屑なだれ堆積物を調査した音波探査の結果,海底岩屑なだれ堆積物の分布の末端部を確認することに成功したこれらは溶岩流などに認められる急勾配の末端崖は示さないものの,傾斜の変化を示す海域に分布する流れ山は岩屑なだれ堆積物分布末端部では存任せず,流走距離に反比例して規模・分布頻度が小さくなる傾向を示す海域における岩屑なだれ堆積物の分布は,主方向が北東方向と東方向の双頭状の分布を示し,給源からの最大水平流走距離は約20km,最大幅は約15km,分布面積は約126km2であるH/L比は0.06であり,海底を流走した岩屑なだれは同規模の陸上岩屑なだれより流動性が高い傾向がある実際に海中に流入した体積は,探査から求めた海底地形データによって見積もった体積に,薄く広がった部分と流れ山の体積を加えた0.92~120km3と見積もられた

10.5575/geosoc.109.595 article JA The Journal of the Geological Society of Japan 2003-01-01

The objective of this study was to investigate the incidence and characteristics thoracic injuries associated with cardiopulmonary resuscitation (CPR) performed under 2005 2010 guidelines.We evaluated patients who had an out-of-hospital cardiac arrest in (2005 group) 2012 (2010 group). We analyzed rib fractures pneumothoraces received during CPR as determined by medical records image studies.Two hundred ninety-two group 243 were enrolled. number greater than (123 [42.1%] versus 167 [68.7%],...

10.1002/ams2.215 article EN Acute Medicine & Surgery 2016-05-11

Closely spaced sediment slices and cores reveal evidence for recurrent folding in the past 18 ka across tip of a blind thrust fault near Kyoto, central Japan. The slices, 0.4 m wide up to 5.5 long, collected with “geoslicer” technique, exposed 100 stratigraphic cross section that extends fold scarp southern Biwako‐seigan zone. A chronology inferred 109 radiocarbon ages suggests most recent earthquake occurred range A.D. 1060–1260, likely around 1170. Historical accounts strongly support this...

10.1029/2007jb005300 article EN Journal of Geophysical Research Atmospheres 2008-05-01

Title Nagasaki Schizophrenia Study: Relationship Between Ultralong-term Outcome (after 28 years) and Duration of Untreated Psychosis Author(s) Ichinose, Hitoshi; Nakane, Yoshibumi; Hideyuki; Kinoshita, Hirohisa; Ohta, Yasuyuki; Honda, Sumihisa; Ozawa, Hiroki Citation Acta medica Nagasakiensia, 54(3), pp.59-66 ; 2010 Issue Date 2010-03 URL http://hdl.handle.net/10069/23119 Right NAOSITE: University's Academic Output SITE

10.11343/amn.54.59 article EN Acta Medica Nagasakiensia 2010-03-01

Abstract Aim Persistent depressive disorder (PDD) was first introduced in the Diagnostic and Statistical Manual of Mental Disorders 5th edition (DSM‐5), which encompasses numerous different conditions, including dysthymia, recurrent major disorder, double depression, chronic depression. SSRIs are first‐line drugs for treatment PDD; however, not all patients respond to SSRI treatment. Case presentation We describe a woman who diagnosed with PDD. At age 38, patient presented anxiety, reduced...

10.1002/npr2.12228 article EN cc-by Neuropsychopharmacology Reports 2022-01-05

Hyperhidrosis significantly reduces patients' quality of life, with many reporting feeling highly anxious. However, the relationship between hyperhidrosis and anxiety induced by sweating has not been examined in detail. The current study between: (1) presence symptoms, (2) severity, (3) sites most sweating. A cross-sectional web-based survey was conducted among university students, 1080 consenting participants (600 males 480 females; mean age, 18.8 years) were included analysis. items were:...

10.1111/1346-8138.16617 article EN The Journal of Dermatology 2022-10-25

Background Several countries have imposed a mandatory 14‐day period of quarantine on individuals arriving from considered high‐risk for severe acute respiratory syndrome coronavirus‐2 (SARS‐CoV‐2) infection. However, it is not clear how long asymptomatic patients infected with SARS‐CoV‐2 can be an carrier. Case Presentation We experienced case female patient abnormal chest computed tomography findings. She did develop fever during hospitalized isolation. remained reverse...

10.1002/ams2.525 article EN cc-by-nc Acute Medicine & Surgery 2020-01-01

Epidemiological studies of psychotic-like experiences (PLEs) have reported that people who had PLEs during childhood or adolescence higher incidences schizophrenia spectrum disorders other psychiatric later in life than not PLEs. Previous work has shown approximately 15% children the city Tsu In this study, we sought to confirm prevalence early teens living Nagasaki and elucidate associations between psychopathological items. To end, used a self-report questionnaire sample 5,000 stu- dents...

10.11343/amn.56.35 article EN Acta Medica Nagasakiensia 2011-08-01

流域スケールにおける斜面崩壊の潜在的危険度を評価することを目的として,谷密度のみを変数とする簡便な評価手法を提案し,その有効性,適用性を検討した.国土地理院発行2万5千分の1地形図及び10mDEMを用いた地形解析から谷線を抽出し,谷密度を算出した.谷線はコンターの平均曲率(H)から求め,H>0.1を閾値とすることで,谷地形としての再現性が高くなることを確認した.表層崩壊,土石流を主とする既往土砂災害を対象として,災害発生斜面の流域の谷密度と比較した結果,谷密度が高い流域ほど豪雨時に不安定となり崩壊が発生しやすい場所が多く存在すること,また,谷頭付近を発生源とする崩壊が多いなどの傾向が認められた.谷密度と崩壊頻度との関係は,0.5~1.5km2程度の流域において比較的良い相関(r=0.60~0.66)を示した.このことから,対象とする解析領域の大きさを考慮することで,本手法は表層崩壊や土石流といった斜面崩壊の危険度評価に有効な手法となり得ると考えられる.今後さらに既往災害事例との比較を重ね,また,地形地質的素因が谷密度に与える影響を考慮するなどで,様々な崩壊タイプに対する本手法の汎...

10.5110/jjseg.59.472 article JA Journal of the Japan Society of Engineering Geology 2019-02-10

【緒言】腎機能低下のためモルヒネが使用困難であった,内科的,外科的に改善の見込めない末期心不全患者の呼吸困難に対し,オキシコドン注射剤を用いて良好にコントロールできた症例を経験したので報告する.【症例】70歳,男性,拡張型心筋症のため以前より入退院を繰り返し,内科的・外科的治療を行われていた.多量の強心薬および利尿薬を使用するも改善なく呼吸困難の増悪を認めたが,腎機能低下のためにモルヒネの代替薬としてオキシコドン注射剤を使用した.経過中を通して心不全の改善は認めなかったが,少量の持続静注により呼吸困難は改善した.【考察】末期心不全患者は腎機能低下を伴うことが多く,呼吸困難緩和目的のモルヒネ使用が困難であることが多い.慎重な観察下にオキシコドンを代替薬として使用することにより,末期心不全患者の呼吸困難を緩和することができる可能性がある.

10.2512/jspm.11.529 article JA Palliative Care Research 2016-01-01

Abstract Aim Increased exposure to digital gaming content among youth in recent years has raised serious health concerns. Social restrictions such as school closures, imposed worldwide because of the ongoing COVID‐19 pandemic, may increase and lead addictive behavior young people. In this study, we investigated behaviors Japanese students during closures. Methods Students completed questionnaires regarding their living conditions, game‐related behaviors, diagnosis Internet addiction,...

10.1002/pcn5.37 article EN cc-by Psychiatry and Clinical Neurosciences Reports 2022-08-29

症例は57歳の男性. 1994年より, 多発十二指腸ポリープにて経過観察されていた. 1999年4月の上部消化管内視鏡検査にてポリープに混在する2型腫瘍を認め, 生検にて低分化腺癌との結果を得, 6月, 原発性十二指腸癌の診断のもと, 膵頭十二指腸切除術を施行した. 腫瘍は十二指腸第2部のファーター乳頭上部にあり, 1.5×1.2cm, 2型, 印環細胞癌, mp, ly0, v0, INFβ, n (-) であった. 併存する多発十二指腸ポリープは, 異所性胃粘膜を有していた. 腫瘍細胞の由来を検索すべく施行した粘液染色では, 幽門腺やBrunner腺を染めるperiodic acid-schiff (PAS) 陽性で, さらにconcanavalin A (con A) 陰性, high iron diamine-alcian blue (HID-AB) 陽性の腸型であった. 腫瘍は, 併存するポリープの異所性胃粘膜由来でなく, Brunner腺由来と考えられた.

10.5833/jjgs.36.260 article EN cc-by-nc The Japanese Journal of Gastroenterological Surgery 2003-01-01
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