Carolyn Astley

ORCID: 0000-0002-9078-5969
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About
Contact & Profiles
Research Areas
  • Acute Myocardial Infarction Research
  • Cardiac Health and Mental Health
  • Cardiac Imaging and Diagnostics
  • Heart Failure Treatment and Management
  • Patient Satisfaction in Healthcare
  • Telemedicine and Telehealth Implementation
  • Coronary Interventions and Diagnostics
  • Stroke Rehabilitation and Recovery
  • Antiplatelet Therapy and Cardiovascular Diseases
  • Cardiac, Anesthesia and Surgical Outcomes
  • Health Systems, Economic Evaluations, Quality of Life
  • Primary Care and Health Outcomes
  • Cardiac Arrest and Resuscitation
  • Emergency and Acute Care Studies
  • Cardiovascular Function and Risk Factors
  • Heart Rate Variability and Autonomic Control
  • Healthcare Quality and Management
  • Lipoproteins and Cardiovascular Health
  • Patient-Provider Communication in Healthcare
  • Venous Thromboembolism Diagnosis and Management
  • Chronic Disease Management Strategies
  • Clinical practice guidelines implementation
  • Atrial Fibrillation Management and Outcomes
  • Chronic Kidney Disease and Diabetes
  • Acute Kidney Injury Research

Flinders University
2015-2024

South Australian Health and Medical Research Institute
2013-2023

Avenir Health
2022

Okinawa Prefectural College of Nursing
2018-2020

National Heart Foundation of Australia
2016-2018

Macquarie University
2018

Flinders Medical Centre
2007-2016

Johns Hopkins University
2016

Cardiac Society of Australia and New Zealand
2016

George Institute for Global Health
2016

Objectives: To characterise management of suspected acute coronary syndrome (ACS) in Australia and New Zealand, to assess the application recommended therapies according published guidelines. Design, setting patients: All patients hospitalised with or confirmed ACS between 14 27 May 2012 were enrolled from participating sites which identified through public records health networks. Descriptive logistic regression analysis was performed. Main outcome measures: Rates guideline-recommended...

10.5694/mja12.11854 article EN The Medical Journal of Australia 2013-08-01

<h3>Objective</h3> To evaluate the proportion of patients hospitalised with acute coronary syndrome (ACS) in Australia and New Zealand who received optimal inpatient preventive care to identify factors associated care. <h3>Methods</h3> All bi-nationally ACS were identified between 14–27 May 2012. Optimal in-hospital was defined as having lifestyle advice, referral rehabilitation, prescription secondary prevention pharmacotherapies. Multilevel multivariable logistic regression used determine...

10.1136/heartjnl-2013-305296 article EN cc-by-nc Heart 2014-06-09

Objective: To describe the impact of invasive management on 12-month survival among patients with suspected acute coronary syndrome (ACS) in Australia. Design and setting: Prospective nationwide multicentre registry. Patients: Patients presenting to 24 metropolitan 15 non-metropolitan hospitals ST-segment-elevation myocardial infarction (STEMI), high-risk intermediate-risk non-ST-segment-elevation ACS (NSTEACS) between 1 November 2005 31 July 2007. Main outcome measures: Death, (MI) or...

10.5694/j.1326-5377.2008.tb01847.x article EN The Medical Journal of Australia 2008-06-01

Abstract Background: Acute coronary syndromes (ACS) management is now well informed by guidelines extrapolated from clinical trials. However, most of these data have been acquired outside the local context. We sought to describe current patterns ACS care in Australia. Methods: The Coronary Syndrome Prospective Audit study a prospective multi‐centre registry ST‐segment elevation myocardial infarction (STEMI), high‐risk non‐ST‐segment (NSTEACS‐HR) and intermediate‐risk (NSTEACS‐IR) patients,...

10.1111/j.1445-5994.2007.01435.x article EN Internal Medicine Journal 2007-07-23

BackgroundDespite the highest levels of evidence on cardiac rehabilitation (CR) effectiveness, its translation into practice is compromised by low participation.AimThis study aimed to investigate CR utilisation and effectiveness in South Australia.MethodsThis retrospective cohort used data linkage clinical administrative databases from 2016 2021 assess association between (no received, commenced without completing, or completed) composite primary outcome (mortality/cardiovascular...

10.1016/j.hlc.2024.01.018 article EN cc-by Heart Lung and Circulation 2024-03-05

Background— High-sensitivity troponin T (hs-TnT) assays promise greater discrimination of evolving myocardial infarction, but the impact unguided implementation on effectiveness care is uncertain. Methods and Results— We evaluated hs-TnT reporting outcome among chest pain patients presenting to 5 emergency departments within a multicenter randomized trial. Patients were allocated (hs-report) or standard (std-report; Roche Elecys). The primary end point was death new recurrent acute coronary...

10.1161/circoutcomes.115.002488 article EN Circulation Cardiovascular Quality and Outcomes 2016-08-10

To assess the impact of availability a catheterisation laboratory and evidence-based care on 18-month mortality rate in patients with suspected acute coronary syndromes (ACS).Management outcomes are described for enrolled 2012 Australian New Zealand SNAPSHOT ACS audit. Patients were stratified according to their presentation hospitals or without cardiac facilities. Data linkage ascertained patient vital status 18 months after admission. Descriptive Cox proportional hazards analyses...

10.5694/mja15.00504 article EN The Medical Journal of Australia 2015-10-29

Objectives: To compare the use of evidence-based pharmacological and invasive treatments 12-month mortality rates between patients with without diabetes who present acute myocardial infarction (MI), to explore relationship these late clinical outcomes. Design setting: Prospective, nationwide multicentre registry: Acute Coronary Syndrome Prospective Audit (ACACIA). Patients: Patients presenting 24 metropolitan 15 non-metropolitan hospitals coronary syndrome (ACS) a final discharge diagnosis...

10.5694/j.1326-5377.2009.tb03306.x article EN The Medical Journal of Australia 2009-11-01

Background— An evidence-practice gap in acute coronary syndromes (ACS) is commonly recognized. System, provider, and patient factors can influence guideline adherence. Through using facilitators the clinical setting, uptake of evidence-based recommendations may be increased. We hypothesized that (systems, tools, workforce) cardiac care were associated with increased adherence decreased adverse outcome. Methods Results— A cross-sectional evaluation was conducted Australian hospitals. The...

10.1161/circoutcomes.110.960229 article EN Circulation Cardiovascular Quality and Outcomes 2011-08-31

Introduction Despite extensive evidence of its benefits and recommendation by guidelines, cardiac rehabilitation (CR) remains highly underused with only 20%–50% eligible patients participating. We aim to implement evaluate the Country Heart Attack Prevention (CHAP) model care improve CR attendance completion for rural remote participants. Methods analysis CHAP will apply large-scale knowledge translation develop a in Australia. Partnering patients, clinicians health service managers, we...

10.1136/bmjopen-2021-054558 article EN cc-by-nc BMJ Open 2022-02-01

Every year, over 65,000 Australians experience an acute coronary syndrome (ACS) and around one-third occur in people with prior heart disease. Cardiac rehabilitation (CR) aims to prevent a repeat ACS by supporting patients' return active fulfilling lifestyle. CR programs are efficacious, but audits of clinical practice show variability program delivery, which may compromise patient outcomes. Core components, quality indicators accreditation have been introduced internationally increase...

10.1186/s12913-022-07667-2 article EN cc-by BMC Health Services Research 2022-02-28

Moderate to severe impairment of renal function has emerged as a potent risk factor for adverse short- and long-term outcomes among patients presenting with cardiac disease.We sought define the clinical, late mortality economic burden this intensive care.A clinical audit care was undertaken between July 2002 June 2003. All diagnoses were included in study. Baseline creatinine levels assessed all patients. Late by interrogation National Death Register. Renal defined estimated glomerular...

10.1111/j.1445-5994.2006.01012.x article EN Internal Medicine Journal 2006-02-27

Chronic kidney disease (CKD) is associated with poor outcomes after acute coronary syndromes, yet selection for invasive investigation and management low.Patients presenting ST segment elevation myocardial infarction (STEMI) or intermediate- to high-risk non-ST syndrome (NSTEACS) (n=2597) were stratified into groups based on function, defined as normal (glomerular filtration rate (GFR)≥60mL/min/1.73m(2) ), moderate CKD (GFR 30-59mL/min/1.73m(2) ) severe <30mL/min/1.73m(2)). Based these...

10.1111/j.1445-5994.2010.02361.x article EN Internal Medicine Journal 2010-10-08
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