A5068473216- Electrochemical Analysis and Applications
- Molecular Junctions and Nanostructures
- Advanced biosensing and bioanalysis techniques
- Ionic liquids properties and applications
- Electrochemical sensors and biosensors
- Conducting polymers and applications
- Electrodeposition and Electroless Coatings
- DNA and Nucleic Acid Chemistry
- Analytical Chemistry and Sensors
- Electrocatalysts for Energy Conversion
- 2D Materials and Applications
- Surface Chemistry and Catalysis
- Quantum Dots Synthesis And Properties
- Force Microscopy Techniques and Applications
- Chalcogenide Semiconductor Thin Films
- RNA and protein synthesis mechanisms
- Gas Sensing Nanomaterials and Sensors
- RNA Interference and Gene Delivery
- Nanofabrication and Lithography Techniques
- Molten salt chemistry and electrochemical processes
- Chemical and Physical Properties in Aqueous Solutions
- CO2 Reduction Techniques and Catalysts
- Spectroscopy Techniques in Biomedical and Chemical Research
- Polymer Surface Interaction Studies
- Catalysis for Biomass Conversion
Université Libre de Bruxelles
2014-2024
Leefmilieu Brussel
2016-2018
Laboratoire de Mathématiques d'Orsay
2016-2018
Laboratoire Chimie Electrochimie Moléculaires et Chimie Analytique
2016
University of Liverpool
2008-2011
Czech Academy of Sciences, Institute of Biophysics
2009-2011
Czech Academy of Sciences
2009-2011
University of Oxford
2010
In-Q-Tel
2010
Institute of Biophysics
2009
High performance chemical sensor is highly desirable to detect traces of toxic gas molecules. Two dimensional (2D) transition metal dichalcogenides (TMDC) semiconducting materials has attracted as high device applications due unique properties such surface volume ratio. Here, we describe the utilization single-layer MoSe2 high-performance room temperature NH3 sensors. Our based shows comprehensible detection down 50 ppm. We also confirmed sensing measurement by recording Raman spectra before...
Because electron transfer is often highly sensitive to bridge length and molecular conformation, changes in these can have a large impact on the conductance of single molecule electrical junctions. In this study, pH used control conformation effective junctions containing peptide sequence H(EL)5C (where H stands for histidine, E glutamic acid, L leucine, C cysteine). The ionizable acid residues result an oligo-peptide structure pH. At low pH, exists its more compact α-helical state, while at...
A colorimetric platform for the fast, simple, and selective detection of proteins medical interest is presented. Detection based on aggregation two batches peptide functionalized gold nanoparticles via dual-trapping protein interest. As proof concept, we applied our to oncoprotein Mdm2. The aptamers used functionalization are reported binding sequences p53 p14 oncoprotein. Rapid aggregation, a color change from red purple, was observed upon addition Mdm2 with concentrations as low 20 nM....
The redox couple resazurin-resorufin exhibits electrofluorochromic properties which are investigated herein by absorption and fluorescence spectroelectrochemistry electrochemically coupled-fluorescence confocal laser scanning microscopy (EC-CLSM). At pH 10, the highly fluorescent resorufin dye is generated at electrode surface electrochemical reduction of poorly resazurin. Performing EC-CLSM surfaces allows to monitor spatially resolved processes in situ real time. Using a small (315 μm...
Amplex Red (AR) is a very useful chemical probe that employed in biochemical assays. In these assays, the non-fluorescent AR converted to resorufin (RS), which strongly absorbs visible region (λabs = 572 nm) and yields strong fluorescence (λfluo 583 nm). Even if commonly used report on enzymatic oxidase activities, an increasing number of possible interferences have been reported, thus lowering accuracy so-called assay. As redox-based reaction, we propose here directly promote conversion RS...
The hydrogen evolution reaction is catalyzed by peptides and proteins adsorbed on electrode materials with high overpotentials for this reaction, such as mercury. catalytic response characteristics are known to be very sensitive the composition structure of investigated biomolecule, opening way implementation a label-free, reagentless electroanalytical method in protein analysis. Herein, it shown using model peptide Cys-Ala-Ala-Ala-Ala-Ala that interfacial organization significantly...
Abstract Analytical performance (selectivity, sensitivity, limit of detection) a sensor is ultimately connected to the interfacial architecture sensing surface that needs be optimized. Self‐assembly mixed monolayer thiolated probes and diluent onto gold surfaces used in design biosensing platforms nowadays commonly performed by two‐step immobilization procedure. In this work, merits one‐step coadsorption procedure are emphasized, it shown ionic strength very efficient tool fine control...
Abstract Potential controlled electrolyses of [BMIm][NTf 2 ] ionic liquid were performed at a gold cathode under nitrogen atmosphere. The structures the major conversion products BMIm + cation elucidated on basis 1D and 2D nuclear magnetic resonance (NMR) analyses gas chromatography (GC) analysis volatile compounds. Recombination imidazol‐2‐yl radicals, generated electrode by single electron transfer, leads to neutral diastereomeric dimers in equal proportions, with faradaic efficiency 80 %,...
The electrochemistry of tellurium in two different deep eutectic solvents, choline chloride - urea (ChCl-U) and oxalic acid (ChCl-Ox) was studied on glassy carbon (GC) polycrystalline (Au(poly)) gold electrodes by cyclic hydrodynamic voltammetries. Voltammetric responses associated with the redox pairs Te(IV)/Te(0) Te(0)/Te(-II) are recorded, a striking difference between ChCl-U ChCl-Ox being observed kinetics couple, which is electrochemically reversible but highly irreversible ChCl-U. This...
The vibrational properties of the 2-mercaptobenzimidazole (MBI) molecule in interaction with gold were examined by a combined approach FTIR measurements and density functional theory (DFT). A complete assignment 42 normal modes MBI has been performed on basis DFT calculations at B3PW91 level complement to Raman spectra. Calculations demonstrated that, deprotonated molecule, negative charge is localized sulfur atom, favoring formation gold-sulfur bond upon reaction gold. This was confirmed...
Abstract It has been shown that peptides and proteins produce at nanomolar concentrations a structure‐sensitive chronopotentiometric peak H mercury electrodes, which is due to the catalytic hydrogen evolution reaction (HER). Herein, we use for first time poly(amino acids) obtain information about role of individual amino acid residues in HER. At pH 6 polylysine (polyLys) polyarginine,tryptophan yield H, agreement with their ionization state, while polyglutamic gives no response. PolyLys...