A5013652463- melanin and skin pigmentation
- Biochemical Analysis and Sensing Techniques
- Trace Elements in Health
- RNA regulation and disease
- Human Mobility and Location-Based Analysis
- Gastrointestinal Bleeding Diagnosis and Treatment
- Gastrointestinal disorders and treatments
- Vector-borne infectious diseases
- Atherosclerosis and Cardiovascular Diseases
- Viral Infections and Vectors
- Drug Transport and Resistance Mechanisms
- Plant Gene Expression Analysis
- Platelet Disorders and Treatments
- Vasculitis and related conditions
- Kawasaki Disease and Coronary Complications
- Iron Metabolism and Disorders
- CRISPR and Genetic Engineering
- Eosinophilic Disorders and Syndromes
- Mosquito-borne diseases and control
- COVID-19 and Mental Health
- Digital Mental Health Interventions
- Computational and Text Analysis Methods
- Heavy Metal Exposure and Toxicity
- Gastrointestinal Tumor Research and Treatment
- Skin Protection and Aging
Bharat Electronics (India)
2024-2025
University of Calcutta
2019-2024
Bharat Biotech (India)
2023
Institute of Post Graduate Medical Education and Research
2017-2022
Bose Institute
2018
Wilson’s disease (WD) is a rare autosomal recessive copper metabolism disorder that primarily affects hepatic and neuronal tissues. The condition caused by mutations in the ATP7B gene. Our group conducted extensive molecular genetic studies, identifying 13 clinically diagnosed Indian WD patients lacking coding variant of 17 with single mutated allele. We hypothesize these patients, unidentified may reside cis-regulatory elements or WD-like phenotype results from cumulative effect...
The aim of this study was to assess the clinico-laboratory parameters, complications and therapeutic responses in children with scrub typhus Eastern India.In prospective, observational study, all (age, <12 years) suspected a compatible clinical scenario were enrolled consecutively over six months. Cases confirmed by means positive IgM serology or Weil-Felix reaction (OXK = 1/80 above) administered enteral doxycycline (4.5 mg/kg/day).Out 94 recruited children, 61 had (mean age 6.1 years, M:F...
Abstract Oculocutaneous albinism (OCA) is a group of congenital autosomal recessive disorders with seven known subtypes (OCA1–OCA7) characterized by loss or absence pigmentation in the skin, hair, and eyes. OCA1, caused pathogenic variations tyrosinase ( TYR ) gene, has been documented to be most prevalent subtype across world including India. In present study, we recruited 53 OCA‐affected individuals from 45 unrelated families belonging 20 different marriage groups/ethnicities 15 districts...
The differential expression of genes involved in xenobiotic metabolism and DNA repair has been implicated the etiology cigarette smoke-related lung cancer. Our research group previously identified 22 gene expression-correlated DNAse hypersensitive sequence-single nucleotide variants (SNVs) with regulatory potential to modulate transcription seven metabolisms genes, thereby contributing individual susceptibility In this study, we evaluated genetic association between cancer two SNVs (rSNVs)...
Lifestyle diseases significantly contribute to the global health burden, with lifestyle factors playing a crucial role in development of depression. The COVID-19 pandemic has intensified many determinants This study aimed identify and demographic associated depression symptoms among Indians during pandemic, focusing on sample from Kolkata, India. An online public survey was conducted, gathering data 1,834 participants (with 1,767 retained post-cleaning) over three months via social media...
Abstract Background Wilson's disease (WD) is a rare copper metabolism disorder with hepatic and neurological symptoms. Dopamine β hydroxylase ( DBH ) encodes copper‐dependent mono‐oxygenase that converts dopamine to norepinephrine, thereby regulating the endogenous content in neurons. Polymorphisms of have been reported be associated several diseases, such as Parkinson's disease, Alzheimer's schizophrenia attention‐deficit hyperactivity disorder, which overlapping symptoms WD. The present...
<br><b>Background:</b> The pediatric vasculitides are multisystem autoimmune disorders involving the blood vessels of varying sizes. Wide geographic and ethnic variations noted in terms incidence clinical features.<br><b>Materials Methods:</b> This prospective, observational study was carried out over a period 4 years from 2015 February to 2019 tertiary care referral hospital delineate epidemiological pattern, features, pathological characteristics vasculitides. All consecutive patients with...
Abstract Lifestyle diseases are the leading cause of global health-related burden. A wide range lifestyle factors has been shown to affect pathogenesis depression. The emergence COVID-19 pandemic created an environment in which many determinants depression exacerbated. This study aims at identifying potential and demographic associated with symptoms among Indians during pandemic. In this regard, we conducted online public survey Kolkata, India, from random voluntary participants collect data...
The Journal is the primary organ of Continuing Paediatric Medical Education in Sri Lanka. journal also has a website. Free full text access available for all readers.The Lanka Child Health now indexed SciVerse Scopus (Source Record ID 19900193609), Index Medicus South-East Asia Region (IMSEAR), CABI (Centre Agriculture and Bioscience International Global Database), DOAJ Google, as well Google Scholar.The policies are modelled on Committee Publication Ethics (COPE) Guidelines Principles...