A5016783347- Nanoparticles: synthesis and applications
- Cancer therapeutics and mechanisms
- Graphene and Nanomaterials Applications
- Lung Cancer Research Studies
- SARS-CoV-2 and COVID-19 Research
- Computational Drug Discovery Methods
- Bacterial biofilms and quorum sensing
- COVID-19 Clinical Research Studies
- Nanocluster Synthesis and Applications
- Carbon and Quantum Dots Applications
- Diagnosis and treatment of tuberculosis
- Antimicrobial Peptides and Activities
- COVID-19 epidemiological studies
- Tuberculosis Research and Epidemiology
- Pain Mechanisms and Treatments
- Advanced Malware Detection Techniques
- PARP inhibition in cancer therapy
- Plasma Applications and Diagnostics
- Biochemical and Structural Characterization
- Medicinal Plants and Neuroprotection
- Antimicrobial agents and applications
- Retinal Diseases and Treatments
- Vanadium and Halogenation Chemistry
- Phytochemicals and Medicinal Plants
- Anomaly Detection Techniques and Applications
Indian Institute of Information Technology Allahabad
2018-2024
INTI International University
2023
King George's Medical University
2023
Institut de Neurosciences Cognitives et Intégratives d’Aquitaine
2021
Centre National de la Recherche Scientifique
2021
WinnMed
2021
Precision Therapeutics (United States)
2021
Tehran University of Medical Sciences
2021
Children's Medical Center
2021
Goethe University Frankfurt
2021
Deep learning models are widely used for various purposes such as face recognition and speech recognition. However, researchers have shown that these vulnerable to adversarial attacks. These attacks compute perturbations generate images decrease the performance of deep models. In this research, we developed a toolbox, termed SmartBox, benchmarking attack detection mitigation algorithms against SmartBox is python based toolbox which provides an open source implementation algorithms. Extended...
Due to the enhanced resistance of bacteria antibiotics, researchers always try find effective alternatives treat drug-resistant bacterial infections. In this context, we have explored antimicrobial peptides (AMPs), which are a broad class small peptide molecules, and investigated their efficacy as potent antibacterial antibiofilm agents. AMPs can cause cell death either through disruption membrane or by inhibiting vital intracellular functions, binding RNA, DNA, components upon transversion...
The present work reports a novel method for fabricating nanocomposites (NCs) using Magnesium Oxide (MgO) and Zinc (ZnO) nanoparticles (NPs) via modified sol-gel route. Furthermore, hydroxyapatite was composited with MgO/ZnO NCs to form (HA)-based bio-ceramics (BCs) enhanced antibacterial mechanical properties. X-ray diffraction, Fourier transform infrared spectroscopy, field emission scanning electron transmission microscopy, energy-dispersive spectroscopy were used perceive their structural...
Nearly 80% of human chronic infections are caused due to bacterial biofilm formation. The increased resistance against the conventional antimicrobial agents makes it difficult treat biofilm-related infections. antibiotics developed by planktonic cells has also become a major threat for human. Therefore, we have attempted here develop an effective alternative strategy overcome issues bacteria. Upon synthesis, biogenic C-dots were combined with lysozymes which further encapsulated into...
Cancer care has become a challenge with the current COVID-19 pandemic scenario. Specially, cancers like small cell lung (SCLC) are difficult to treat even in normal situation due their rapid growth and early metastasis. For such patients, treatment can't be compromised must taken ensure minimum exposure ongoing spread of infection. this reason, in-house treatments being suggested for these patients. Another issue is that symptoms SCLC match well Hence, detection may also get delayed leading...
Biofilm infections are highly resistant to commercial antibiotics. Therefore, developing a potent agent against such drug-resistant bacterial is desirable. Here, we synthesized positively charged silver nanoclusters (Ag NCs) with diameter of <2 nm, which were found be very effective antibacterial and antibiofilm agents tetracycline-resistant Bacillus subtilis most importantly multidrug-resistant pathogenic strains Pseudomonas aeruginosa Acinetobacter baumannii. Ag NCs able both prevent...
Remdesivir, a C-nucleotide prodrug binds to the viral RNA-dependent-RNA polymerase (
Radiation resistance is one of the major problems in treatment small cell lung cancer (SCLC). Most these patients are given radiation as first-line and it was observed that initial response very good. However, they show relapse a few months which also associated with to treatment. Thus, targeting mechanism by cells develop could be an important strategy improve survival chances patients. From RNA-Seq data analysis, identified CHEK1 gene overexpressed. Chk1 protein encoded involved SCLC. It...
Association of peripheral neuropathy with diabetic retinopathy is known but the relationship preclinical various grades not well documented. This study evaluated association using nerve conduction studies retinopathy.Cases asymptomatic for underwent lower limbs Caldwell machine and Sierra wave software. The risk factors were analyzed by bivariate multivariate regression analysis.The overall prevalence was 75.6% (sensory 58.54% combined motor sensory 17.1%) increase in severity retinopathy....
Abstract Introduction: Immune checkpoint blockade (ICB) has revolutionized the treatment of many cancers, still most patients do not respond to PD-1 or CTLA-4 inhibitors. Thus, new Immuno-Oncology (IO) therapies that could potentially benefit non-responding are greatly needed. Jounce generated cell type-specific gene signatures as a means probing The Cancer Genome Atlas and other large datasets for novel IO targets. Regulatory T cells (Tregs) one attractive type targeting they may contribute...
### Learning Point for Clinicians Tuberculosis should be kept as a possibility in patients with multisystem disease, especially developing countries like India. A simple test CT guided FNAC can help detect infection M. tuberculosis and hence major surgery avoided CA-125 is an epithelial marker derived from coelomic epithelium. It elevated 90% of advanced ovarian cancers has sensitivity 57–80% specificity 100%. Therefore, CA-125 important investigation evaluating pelvic mass. However, any...
Abstract Funding Acknowledgements Type of funding sources: None. Background Morphological features neointimal tissue play a pivotal role in the pathophysiology In-Stent Restenosis (ISR) after percutaneous coronary intervention, hence understanding these and patterns is crucial. Purpose The present study was designed to qualitatively quantitatively assess characteristics lesions using OCT patients presenting with ISR. Methods This single-center, prospective, observational performed between...