A5035219695- Neuroendocrine Tumor Research Advances
- Lung Cancer Research Studies
- Gastric Cancer Management and Outcomes
- Cancer therapeutics and mechanisms
- Neuroblastoma Research and Treatments
- Helicobacter pylori-related gastroenterology studies
- Esophageal Cancer Research and Treatment
- Eosinophilic Esophagitis
- Colorectal Cancer Screening and Detection
- Metastasis and carcinoma case studies
- Gastroesophageal reflux and treatments
- Esophageal and GI Pathology
- Cancer, Stress, Anesthesia, and Immune Response
- Peripheral Artery Disease Management
- Cardiovascular Health and Disease Prevention
- Ovarian cancer diagnosis and treatment
- Genetic factors in colorectal cancer
- Clostridium difficile and Clostridium perfringens research
- Head and Neck Cancer Studies
- Cancer Diagnosis and Treatment
- Antimicrobial Resistance in Staphylococcus
- Nosocomial Infections in ICU
- Bacterial Identification and Susceptibility Testing
- Clusterin in disease pathology
- Salivary Gland Tumors Diagnosis and Treatment
Stanford University
2012-2025
Stanford Medicine
2023
Columbia University
2020
Columbia University Irving Medical Center
2018-2020
Royal College of Physicians
2020
University of California, San Francisco
2015-2017
University of California, Davis
2013
Icahn School of Medicine at Mount Sinai
2013
Mount Sinai Hospital
2013
Cardiovascular Institute of the South
2013
Small cell lung cancer (SCLC) is an aggressive neuroendocrine subtype of with high mortality. We used a systematic drug repositioning bioinformatics approach querying large compendium gene expression profiles to identify candidate U.S. Food and Drug Administration (FDA)-approved drugs treat SCLC. found that tricyclic antidepressants related molecules potently induce apoptosis in both chemonaïve chemoresistant SCLC cells culture, mouse human tumors transplanted into immunocompromised mice,...
Summary Data on Barrett’s esophagus (BE) and esophageal cancer (EC) outcomes in patients with eosinophilic esophagitis (EoE) are limited. We aimed to determine the risk of prevalent BE (<1 year after endoscopy), incident (≥1 EC versus without EoE, identify predictors BE/EC EoE patients. identified adult Merative MarketScan Database who underwent first-time upper endoscopy between 2008 2020. Chi-square analysis compared proportions had or EC. Multivariate Cox regression determined...
Abstract Background As survival with metastatic colorectal cancer (CRC) and imaging modalities improve, detection of ovarian metastases may be increasing. The ovary serve as a sanctuary site for malignant cells; however, there is paucity data regarding the role oophorectomy. Methods This single-institution retrospective study patients CRC from 2009 to 2017. We evaluated patient, disease, treatment related factors associated overall (OS) initial diagnosis CRC. Results Of 108 assessed, median...
Background— The Walking Impairment Questionnaire (WIQ) is a subjective measure of patient-reported walking performance developed for peripheral arterial disease. purpose this study to examine whether simple tool can improve the predictive capacity established risk models and WIQ be used in patients without Methods Results— At baseline we assessed distance, stair-climbing, speed category scores among individuals who were undergoing coronary angiography. During median follow-up 5.0 years,...
While colon endoscopic mucosal resection (EMR) is an effective technique, removal of larger polyps often requires piecemeal resection, which can increase recurrence rates. Endoscopic submucosal dissection (ESD) in the offers ability for en bloc and well-described Asia, but there are limited studies comparing ESD vs EMR West.To evaluate different techniques large to identify factors recurrence.The study a retrospective comparison ESD, knife-assisted performed at Stanford University Medical...
Abstract Background Treatment for squamous cell carcinoma (SCC) of unknown primary consists radiotherapy (RT) +/‐ chemotherapy or neck dissection adjuvant RT/chemoradiotherapy (CRT). We compared these strategies and identified prognostic factors. Methods From 1993 to 2015, 75 patients with SCC had RT‐based surgery‐based treatment. Primary endpoints were overall survival (OS) disease‐free (DFS). Event‐time distributions estimated using the Kaplan‐Meier method. Results Five‐year OS DFS...
Esophageal 24-hour pH/impedance testing is routinely performed to diagnose gastroesophageal reflux disease. Interpretation of these studies time-intensive for expert physicians and has high inter-reader variability. There are no commercially available machine learning tools assist with automated identification events in studies.A system identify was developed, which included an initial signal processing step a model. Gold-standard were defined by group physicians. Performance metrics...
Background: The incidence and mortality of colorectal cancer (CRC) are increasing in adults under 50 years. Risk factors associated with early-onset neoplasia (CRN) uncertain. We aimed to identify clinical predictors the presence CRN detected by diagnostic colonoscopy symptomatic individuals years age. Methods: used a single-center endoscopy database patients 18–49 age who underwent ambulatory between 2007 2017. Pathology reports identified as adenomas, advanced adenomas (based on size or...
Recent data suggest that subcutaneous adiposity represents an independent prognostic marker in cancer. We aimed to determine whether estimated by the tissue index (SATI) was associated with mortality esophageal cancer.We conducted a retrospective analysis of prospectively enrolled cohort from 2009 2015 cancer at two major centers. CT scans for initial staging were used quantify and skeletal muscle areas. Subjects categorized as above or below median SATI using sex-specific values. Sarcopenia...
The recent global food security crisis is garnering increasing attention and calls for innovative solutions to mitigate its negative impacts on people, especially the most economically vulnerable. In urban regions, this issue aggravated by fact that, one hand, rapid urbanization greater levels diversity of consumption associated with growing affluence inhabitants has led rising demand, while other loss farmland due expansion or irrational sprawl extreme weather events agricultural producers...