A5018575890- Spine and Intervertebral Disc Pathology
- Spinal Fractures and Fixation Techniques
- Glioma Diagnosis and Treatment
- Musculoskeletal pain and rehabilitation
- Meningioma and schwannoma management
- Medical Imaging and Analysis
- Anesthesia and Pain Management
- Bone Tumor Diagnosis and Treatments
- Cervical and Thoracic Myelopathy
- Head and Neck Surgical Oncology
- Traumatic Brain Injury and Neurovascular Disturbances
- Pelvic and Acetabular Injuries
- Brain Metastases and Treatment
- Radiomics and Machine Learning in Medical Imaging
- Pituitary Gland Disorders and Treatments
- MicroRNA in disease regulation
- Neurological disorders and treatments
- Management of metastatic bone disease
- Scoliosis diagnosis and treatment
- Neurofibromatosis and Schwannoma Cases
- Neurosurgical Procedures and Complications
- Anesthesia and Sedative Agents
- Spinal Hematomas and Complications
- Airway Management and Intubation Techniques
- Neuroscience and Neural Engineering
Palacký University Olomouc
2014-2025
University Hospital Olomouc
2014-2024
Ocní klinika
2008-2019
Johns Hopkins Hospital
2013
The University of Texas MD Anderson Cancer Center
2013
National Institute of Mental Health and Neurosciences
2013
Columbia University
2013
Orlando Health
2013
Ocná klinika
2010
The annual number of spinal fusion procedures has been increasing and is well documented worldwide. O-arm slowly becoming the standard for transpedicular screw insertion. accuracy safety this method have confirmed by many studies. Therefore, learning curve its use younger surgeons focus our investigation. Longer operative time radiation exposure to patient are only disadvantages. Our aim was evaluate neurosurgical residents receiving specialist training demonstrate compared conventional...
Aim: To determine the accuracy of modified Mallampati test for predicting difficult tracheal intubation. Design: A cross-sectional, clinical, observational, non-blinded study. quality analysis anesthetic care. Setting. Operating theatres and department anesthesiology in a university hospital. Material methods: Following local ethics committee approval patients' informed consent to anesthesia, all adult patients (> 18 yrs) presenting any type non-emergency surgical procedures under general...
The aim of this study was to compare the complication rate traditional minimally invasive anterior with new lateral trans-psoatic retroperitoneal approaches intervertebral discs at levels T12-L5.A review all cases (ALIF) and (XLIF) disc surgery T12-L5, treated Department Neurosurgery from January 1996 September 2011. ALIF group consisted 120 XLIF 88 patients. Preoperative diagnoses were: degenerative disease, failed back syndrome, spondylolisthesis, retrolisthesis posttraumatic injury....
Aims: To compare the pharmacodynamics of 0.6 mg kg-1 rocuronium in young and older patients both genders during total intravenous anesthesia. Methods: Following local ethics committee approval informed consent, scheduled for surgery under anesthesia (propofol/sufentanil) were divided into 4 study groups: 37 males aged 20-40, 40 60-75 yrs, 43 females 20-40 38 yrs. Neuromuscular block following (0.6 kg-1) was monitored: train-of-four [TOF] stimulation ulnar nerve at 15-s intervals, EMG...
Failed endotracheal intubation and inadequate ventilation with subsequent insufficient oxygenation can result in serious complications potentially leading to permanent health damage. Difficult may occur not only patients apparent pathologies the orofacial region but also, unexpectedly, those without abnormalities. This study aimed at finding anthropometric parameters that are easy examine would aid predicting difficult intubation.A case-control was undertaken. Based on defined criteria, 15...
Meningioma growth rates are highly variable, even within benign subgroups, with some remaining stable, whereas others grow rapidly.To identify molecular-genetic markers for more accurate prediction of meningioma recurrence and better-targeted therapy.Microarrays identified microRNA (miRNA) expression in primary recurrent meningiomas all World Health Organization (WHO) grades. Those found to be deregulated were further validated by quantitative real-time polymerase chain reaction a cohort 172...
The surgical treatment of paediatric thalamic gliomas has been burdened with high morbidity, and these lesions were often considered inoperable. With new approaches intraoperative technologies, we can remove tumours once deemed In our single centre, have operated on 11 patients over the course 8 years. We performed eight GTR resections three intended subtotal resections. postoperative neurological deficit ranged from mild to very severe for motor weakness none aphasia after surgery, all...
Patients below 55 years were genetically studied because the prevalence of isocitrate dehydrogenase 1 (IDH1) decreases in older patients and on grounds cost-effectiveness, as suggested by World Health Organization (WHO) 2016. The aim our study was to use novel massively parallel sequencing (MPS) approaches examine rare variants IDH1/2 Czech diffuse astrocytic oligodendroglial tumors (gliomas) age who had been immunohistochemically (IHC) diagnosed IDH1 R132H negative. IHC status (wild type or...
PURPOSE OF THE STUDYEach dynamic stabilisation should preserve motion at the operated segment as well reduce a load on disc and intervertebral joints.One of methods to achieve this is implantation interspinous spacers between lumbar spinous processes.In study, patients treated with DIAM spacer (Medtronic, USA) were prospectively followed up aim evaluate clinical outcomes post-operative complications. MATERIALPatients degenerative disease lumbosacral spine indicated for operation.They...
The aim of this study was to identify retrospectively, lumbar sympathectomy (SE) using thermography (TG) and evaluate clinically, the severity post-sympathectomy (post-SE) dysfunction after anterior lateral interbody fusion procedures (ALIF, XLIF).Twenty eight patients with suspected SE were referred for TG both legs. They completed our questionnaire on difficulties SE. We evaluated ability physical examinations reveal in contrast compared symptoms (warmer leg inhibited sweating) responses...
Aim: To determine the inter-observer reproducibility of 15 tests used for predicting difficult tracheal intubation (DI). Material and methods: Following local ethics committee approval informed consent, 101 volunteers were examined by two assessors using DI. The who blinded to results other, each volunteer independently. Cohen's kappa (κ) or first-order agreement coefficient (AC1) measure between assessor ratings on a qualitative scale. Agreement quantitative outcomes was described...
We present a case report of female patient with metastasis breast carcinoma to the medullary conus and cauda equina.A 48-year-old woman history tumor, suddenly felt severe weakness numbness lower extremities. MRI spine disclosed mass lesion within conus, leptomeningeal involvement equina at spinal level L1. Laminectomy was performed partial resection tumor especially release nerve roots achieved using microsurgical techniques.Her clinical status, right leg sensory loss in extremities have...
Glioblastoma inevitably recurs, but no standard regimen has been established for treating this recurrent disease. Several reports claim that reoperative surgery can improve survival, the effects of reoperation timing on survival have rarely investigated. We, therefore, evaluated relationship between and in GBM. A consecutive cohort unselected patients (real-world data) from three neuro-oncology cancer centers was analyzed (a total 109 patients). All underwent initial maximal safe resection...
Aim: The aim of this study was to compare resection and biopsy glioblastoma (GBM) in eloquent brain areas (EBA). Methods: This a prospective evaluation 38 patients with GBM EBA. 22 were treated by surgical 16 biopsy. Preoperative KPS, neurological status size lesion on MRI assessed. One week three months postoperatively Performance Status (PS) WHO evaluated. Extent (EOR) overall survival (OS) described. Overall mean age the 64.3 years, group 47.7 mm 51.0 mm. Results: Worsening or development...
Aim: The aims of this study were to describe the incidence and type perioperative complications that occur with minimally invasive anterior retroperitoneal spinal surgery performed at level L5/S1 intervertebral disc. Methods: A retrospective review 175 patients: 103 women 72 men, average age 45, who had undergone from January 2001 February 2011. preoperative diagnoses were: degenerative disc disease in 87 (50%), failed back syndrome 53 (30%) spondylolisthesis 35 patients (20%). surgical...