A5066794001- Traumatic Brain Injury Research
- Transcranial Magnetic Stimulation Studies
- Parkinson's Disease Mechanisms and Treatments
- Cardiac Arrest and Resuscitation
- Traumatic Brain Injury and Neurovascular Disturbances
- Functional Brain Connectivity Studies
- Cognitive Functions and Memory
- Dementia and Cognitive Impairment Research
- EEG and Brain-Computer Interfaces
- Stroke Rehabilitation and Recovery
- Mind wandering and attention
- Neurological disorders and treatments
- Spatial Neglect and Hemispheric Dysfunction
- Muscle activation and electromyography studies
- Cognitive Abilities and Testing
- Olfactory and Sensory Function Studies
- Ginkgo biloba and Cashew Applications
- Neurobiology of Language and Bilingualism
- ECG Monitoring and Analysis
- Spatial Cognition and Navigation
- Cerebral Palsy and Movement Disorders
- Visual perception and processing mechanisms
- Bone fractures and treatments
- Migraine and Headache Studies
- Musculoskeletal pain and rehabilitation
Edward Hines, Jr. VA Hospital
2014-2024
Nevada State University
2022
Ripley Hospital
2022
Center for Innovation
2014-2021
Northwestern University
2020
George Washington University
2020
New Mexico VA Health Care System
2020
Rehabilitation Research and Development Service
2020
Marianjoy Rehabilitation Hospital
2020
Northwestern Medicine
2020
Objective: Report pilot findings of neurobehavioral gains and network changes observed in persons with disordered consciousness (DoC) who received repetitive transcranial magnetic stimulation (rTMS) or amantadine (AMA), then rTMS+AMA. Participants: Four DoC 1 to 15 years after traumatic brain injury (TBI). Design: Alternate treatment-order, within-subject, baseline-controlled trial. Main Measures: For group individual analyses, predetermined thresholds, based on mixed linear-effects models...
Objective: For persons in states of disordered consciousness (DoC) after severe traumatic brain injury (sTBI), we report cumulative findings from safety examinations, including serious adverse events (AEs) a repetitive transcranial magnetic stimulation (rTMS) parameter protocol 2 different studies. Participants: Seven DoC sTBI with widespread neuropathology, but no large lesions proximity to the site rTMS. One participant had ventriculoperitoneal shunt programmable valve. Methods: Two...
For people with disordered consciousness (DoC) after traumatic brain injury (TBI), relationships between treatment induced changes in neural connectivity and neurobehavioral recovery have not been explored. To begin building a body of evidence regarding the unique contributions treatments to network relative recovery, we conducted pilot study identify meriting additional examination future research. address this objective, examined previously unpublished data derived from randomized clinical...
Background: Biomarkers that can advance precision neurorehabilitation of the traumatic brain injury (TBI) are needed. MicroRNAs (miRNAs) have biological properties could make them well suited for playing key roles in differential diagnoses and prognoses informing likelihood responsiveness to specific treatments. Objective: To review evidence miRNA alterations after TBI evaluate state science relative potential applications TBI-specific miRNAs. Methods: This scoping includes 57 animal human...
To examine the merits of using microRNAs (miRNAs) as biomarkers disorders consciousness (DoC) due to traumatic brain injury (TBI).Acute and subacute beds.Patients remaining in vegetative minimally conscious states (VS, MCS), an average 1.5 years after TBI, enrolled a randomized clinical trial ( n = 6). Persons without diagnosed central nervous system disorder, neurotypical controls 5).Comparison whole blood miRNA profiles between patients age/gender-matched controls. For patients,...
Purpose Examine the psychometric properties of World Health Organization Disability Assessment Schedule 2.0 among U.S. Iraq/Afghanistan Veterans with a combination mild traumatic brain injury and behavioral health conditions using Rasch analysis.Methods 307 were classified as either combat control (n = 141), or one three clinical groups: 10), 24), both 128). Data from groups used to establish step item calibrations serving anchors when including group.Results Measurement precision was...
Limitations in everyday functioning are frequently reported by veterans with a history of mild traumatic brain injury (mTBI) and/or posttraumatic stress disorder (PTSD). Multiple factors associated functional disability among veterans, including depression, poor social support, cognition, and substance use. However, the degree to which these factors, particularly cognitive capacities, contribute limitations remains unclear.We evaluated performance on tests processing speed, executive...
Explore outcome differences of a 12-week home-based RAS-enhanced walking program completed by Veterans with PD and without STN-DBS.
Describe preliminary cognitive effects of 10 sessions high frequency rTMS targeted to the left dorsolateral prefrontal cortex (DLPFC) in Veterans with PD-MCI.
Repetitive Transcranial Magnetic Stimulation (rTMS) is emerging as a promising treatment for persons with disorder of consciousness (DoC) following traumatic brain injury (TBI). Clinically, however, there are concerns about rTMS exacerbating baseline seizure risk. To advance understanding risks, this article reports evidence DoC-TBI rTMS-related
<sec> <title>BACKGROUND</title> Alcohol use disorder and mild traumatic brain injury (AUD+mTBI) commonly co-occur resulting in exacerbation of symptoms, negatively impacting function. The co-occurrence AUD+mTBI theoretically represents a unique heterogenous state that impacts symptoms Repetitive transcranial magnetic stimulation (rTMS) is non-invasive neuromodulatory treatment with burgeoning evidence for improving function AUD mTBI each alone. However, there no consensus on optimal neural...
Abstract Objective Value in evaluating error subtypes on visuospatial line orientation tests has been reported. Directional bias metrics for test errors represent easily quantifiable data that have not previously studied. We evaluated whether patients with a clinical condition known to affect functioning (Parkinson’s disease [PD]) exhibited unique directional patterns the RBANS Line Orientation relative other neuropsychology-referred patients. Method compared overall errors, by location...
Objective: To explore cognitive-related diagnoses and demographics of a large sample Veterans with Parkinson's disease over the last decade. Background: Although cognitive decline in (PD) patients is well recognized, diagnostic codes relationship to war-associated are not studied. US have higher risk brain injuries than general population, including exposure neurotoxins, post-traumatic stress disorder (PTSD), traumatic injury (TBI), which necessitates an independent evaluation this cohort...