A5039215904- Pesticide Residue Analysis and Safety
- Crystallization and Solubility Studies
- X-ray Diffraction in Crystallography
- Pharmaceutical and Antibiotic Environmental Impacts
- Antibiotics Pharmacokinetics and Efficacy
- Analytical Chemistry and Chromatography
- Analytical chemistry methods development
- Aquatic Ecosystems and Phytoplankton Dynamics
- Pesticide and Herbicide Environmental Studies
- Microplastics and Plastic Pollution
- Marine and coastal ecosystems
- Effects and risks of endocrine disrupting chemicals
- Advanced Chemical Sensor Technologies
- Catalytic Cross-Coupling Reactions
- N-Heterocyclic Carbenes in Organic and Inorganic Chemistry
- Toxic Organic Pollutants Impact
- Environmental Toxicology and Ecotoxicology
- Insect and Pesticide Research
- Marine Toxins and Detection Methods
- Liver Disease Diagnosis and Treatment
- Pharmacological Effects and Assays
- Analytical Chemistry and Sensors
- Drug Transport and Resistance Mechanisms
- Mass Spectrometry Techniques and Applications
- Crystallography and molecular interactions
University of Padua
2016-2025
Institute of Condensed Matter Chemistry and Technologies for Energy
2021-2024
National Research Council
2022
Sapienza University of Rome
2003-2009
Istituto Superiore di Sanità
2005-2006
Humans are constantly exposed to microplastics and nanoplastics (MNPs). Although significant gaps remain in our understanding of their adverse effects on human health, it is increasingly evident that MNPs can...
This work is aimed at developing an electrochemical sensor for the sensitive and selective detection of trace levels perfluorooctanesulfonate (PFOS) in water. Contamination waters by perfluorinated alkyl substances (PFAS) a problem global concern due to their suspected toxicity ability bioaccumulate. PFOS compound major concern, as it has lowest suggested control concentrations. The reported here based on gold electrode modified with thin coating molecularly imprinted polymer (MIP), prepared...
Background and Purpose Gut microbiota is essential for the development of gastrointestinal system, including enteric nervous system (ENS). Perturbations gut in early life have potential to alter neurodevelopment leading functional bowel disorders later life. We examined hypothesis that dysbiosis impairs structural integrity ENS, dysmotility juvenile mice. Experimental Approach To induce dysbiosis, broad‐spectrum antibiotics were administered by gavage (3weeks old) male C57Bl/6 mice 14 days....
The study of the molecular cluster Au25(SR)18 has provided a wealth fundamental insights into properties clusters protected by thiolated ligands (SR). This is also because this been particularly stable under number experimental conditions. Very unexpectedly, we found that paramagnetic Au25(SR)180 undergoes spontaneous bimolecular fusion to form another benchmark gold nanocluster, Au38(SR)24. We tested reaction with series Au25 clusters. was confirmed and characterized UV–vis absorption...
Electrochemiluminescence (ECL), an intriguing luminescent phenomenon induced by electrochemical stimulation, has evolved from studying electron transfer reactions to a powerful analytical method and imaging technique. ECL can be generated through annihilation or co-reactant methods, with recent advancements integrating it into devices for diverse applications. This review traces the evolution of its early applications developments in technology. Notably, utilization charge-coupled (CCD)...
A simple and rapid method able to determine residues of 12 sulfonamide (SAs) antibacterials in cattle trout muscle tissues is presented. This based on the matrix solid-phase dispersion technique with hot water as extractant followed by liquid chromatography-mass spectrometry (LC-MS). The LC-MS instrumentation was equipped an electrospray source a single quadrupole. After 0.8 g flesh sample containing analytes deposited sand (crystobalite), this material packed into extraction cell. SAs are...
Microcystins (MCs) and cylindrospermopsin (CYL) are potent natural toxins produced by cyanobacteria (blue-green algae) that grow worldwide in eutrophic freshwaters cause animal human water-based toxicoses. The main purpose of this work has been assessing the contamination levels some MCs CYL Italian lake (Albano) water. To do this, we have developed an original analytical method involving MC extraction with a sorbent (Carbograph 4) cartridge. is highly polar compound scarcely retained any...
Edible seaweeds have been consumed by Asian coastal communities since ancient times.
Glucocorticoids (GCs) are currently used for the therapeutic management of cholestatic diseases, but their use and molecular mechanism remain controversial. The aims this study were 1) to assess effect a 2-week treatment with GC dexamethasone on hepatic damage in bile duct-ligated rats; 2) investigate its activation nuclear receptors (NRs) pregnane X receptor (PXR), constitutive androstane (CAR) (GR), NF-kB, as well oxidative stress acid (BA) composition. Cholestasis was induced by ligation...
Herein, we report a new method to synthesize molecular gold nanoclusters (AuNCs) stabilized by phosphine (PR3) and di-N-heterocyclic carbene (di-NHC) ligands. The interaction of di-NHC gold(I) complexes, with the general formula [(di-NHC)Au2Cl2] well-known [Au11(PPh3)8Cl2]Cl clusters provides three classes AuNCs through controllable reaction sequence. synthesis involves an initial ligand metathesis produce [Au11(di-NHC)(PPh3)6Cl2]+ (type 1 clusters), followed thermally induced...
Acute myeloid leukemia (AML) is the most prevalent form of acute in adults, representing a substantial medical need, as standard care has not changed for past...
Microbial signals trigger the release of neutrophil extracellular traps (NETs) through peptidyl-arginine-deiminase-4 (PADI4). In turn, NETosis can propagate inflammation to distant tissues. We hypothesize that PADI4 mediates interactions between diet-modified microbiota and host metabolism. report in adipose tissue individuals with obesity, was associated dysglycemia. mice, high-fat diet (HFD) induced not only dysmetabolism meta-inflammation but also local systemic signs NETosis. Deleting...
<p dir="ltr">Microbial signals trigger the release of neutrophil extracellular traps (NETs) through peptidyl-arginine-deiminase-4 (PADI4). In turn, NETosis can propagate inflammation to distant tissues. We hypothesize that PADI4 mediates interactions between diet-modified microbiota and host metabolism. report in adipose tissue individuals with obesity, was associated dysglycemia. mice, high-fat diet (HFD) induced not only dysmetabolism meta-inflammation but also local systemic signs...