A5062467240- Antimicrobial Peptides and Activities
- Biochemical and Structural Characterization
- Protein Hydrolysis and Bioactive Peptides
- Chemical Synthesis and Analysis
- Probiotics and Fermented Foods
- Lipid Membrane Structure and Behavior
- Insect and Pesticide Research
- Aquaculture disease management and microbiota
- Advanced Drug Delivery Systems
- Ruminant Nutrition and Digestive Physiology
- Plant and animal studies
- RNA Interference and Gene Delivery
- Insect and Arachnid Ecology and Behavior
- Plant Micronutrient Interactions and Effects
- RNA and protein synthesis mechanisms
- Seed Germination and Physiology
- Magnetic and Electromagnetic Effects
- Biochemical and Molecular Research
- Antimicrobial agents and applications
- Light effects on plants
- Alkaloids: synthesis and pharmacology
- Pesticide and Herbicide Environmental Studies
- Pancreatic function and diabetes
- Agricultural and Food Sciences
- Marine Sponges and Natural Products
Universidade Estadual Paulista (Unesp)
2015-2024
Universidade de São Paulo
2018-2024
Weatherford College
2024
Catholic University of Santa María
2021
Faculdade de Tecnologia e Ciências
2021
Centro Universitário de Araraquara
2014
Abstract Viral membrane fusion is an orchestrated process triggered by membrane-anchored viral glycoproteins. The S2 subunit of the spike glycoprotein from severe acute respiratory syndrome (SARS) coronavirus (CoV) contains internal domains called peptides (FP) that play essential roles in virus entry. Although has been broadly studied, there are still major gaps molecular details lipid rearrangements bilayer during peptide-membrane interactions. Here we employed differential scanning...
ABSTRACT It is well known that cationic antimicrobial peptides (cAMPs) are potential microbicidal agents for the increasing problem of resistance. However, physicochemical properties each peptide need to be optimized clinical use. To evaluate effects dimerization on structure and biological activity Ctx-Ha, we have synthesized monomeric three dimeric (Lys-branched) forms Ctx-Ha by solid-phase synthesis using a combination 9-fluorenylmethyloxycarbonyl (Fmoc) t -butoxycarbonyl (Boc) chemical...
Salinity is an abiotic stress that impacts the plant antioxidative system, leading to increase in lipoperoxide formation membrane, and a subsequent decrease crop productivity. This study aims examine impact of magnetically treated water, applied via fertigation, on tomato plants grown varying concentrations salts. used factorial design (5×2), with five salinity levels through fertigation (1.5; 2.5; 4.0; 5.5 7.0 dSm-1) two forms water treatment (unmagnetized - UW MW), ten replications....
Abstract There is no use restriction associated with bees for many fungicides used in agriculture; however, this does not always mean that these pesticides are harmless nontarget organisms. We investigated whether the fungicide pyraclostrobin, which acts on fungal mitochondria, also negatively affects honey bee mitochondrial bioenergetics. Honey were collected from 5 hives and anesthetized at 4 °C. The thoraces separated, mitochondria isolated by grinding, filtering, differential...
The constant use of synthetic antibiotics as growth promoters can cause bacterial resistance in chicks. Consequently, the these drugs has been restricted different countries. In recent years, antimicrobial peptides have gained relevance due to their minimal capacity for and does not generate toxic residues that harm environment human health. this study, a Ctx(Ile21)-Ha peptide was employed, its previously reported great potential, evaluate application effects laying chicks challenged with...
The increase in bacterial resistance to current antibiotics has led the development of new active molecules. We have isolated antimicrobial peptide Ctx-Ha from skin secretion frog Hypsiboas albopunctatus. aim present work was elucidate mechanism action this peptide. sequence similarity with Ceratotoxin, pore size, and pore-like release carboxyfluorescein vesicles indicated that Ctx(Ile21)-Ha a based on barrel- stave model. In second part work, we synthesized three analogues provide...
Climate change is causing an increase in dry spells, altering rainfall patterns and soil moisture, affecting water nutrient plant uptake, which inevitably affects vegetable production. To mitigate this issue, some technologies that allow the maintenance of ideal moisture for uptake process are being investigated. Considering this, we hypothesize use treated with a magnetic field can efficiency lettuce crop Thus, present study aimed to evaluate effect irrigation rate magnetically on biomass...
Sustainable intensification involves maintaining ecosystem balance and increasing productivity per animal unit area. Phytogenic additives can be used as an alternative to achieve sustainable intensification. Tannins are phenolic compounds present in plants that classified according their chemical structure into hydrolyzable condensed compounds. When added ruminant diets, tannins exert effects on rumen fermentation, such a reduction protein degradation enteric methane production of dry matter...
Abstract Bees can be exposed to pesticides when visiting crops or plants in adjacent areas affected by spray drift. Among pesticide categories, fungicides tend considered relatively safe, though they also negatively affect pollinators. Most evidence of damage bees comes from laboratory tests; there is little information concerning contamination levels the field. We examined exposure honey ( Apis mellifera L.) (Hymenoptera: Apidae) and a common Brazilian native species social stingless...
Antimicrobial peptides (AMPs) isolated from several organisms have been receiving much attention due to some specific features that allow them interact with, bind to, and disrupt cell membranes. The aim of this paper was study the interactions between a membrane mimetic cationic AMP Ctx(Ile21)-Ha as well analogues containing paramagnetic amino acid 2,2,6,6-tetramethylpiperidine-1-oxyl-4-amino-4-carboxylic (TOAC) incorporated at residue positions n = 0, 2, 13. Circular dichroism studies...
Salmonella enterica subsp. serovar Enteritidis (S. Enteritidis) in poultry is most often transmitted by the fecal–oral route, which can be attributed to high population density. Upon encountering innate immune response a host, pathogen triggers stress and virulence factors help it survive host. The aim of this study was evaluate effect hypromellose acetate/succinate (HPMCAS)-coated alginate microparticles containing Ctx(Ile21)-Ha antimicrobial peptide (AMP) on both intestinal colonization...
Abstract Banana is one of the most consumed and popular fruits in all regions world, being cultivated mainly tropical countries. It not only a rich source vitamins A, C, B, calcium, iron, potassium, phosphorus, other nutrients, but it also contains several types antioxidants with high nutritional value. In this context, current study aimed to quantify content ascorbic acid, flavonoids, pigments, minerals present “Nanicão” bananas during ripening process. As demonstrated, level flavonoids was...
The human enzyme dihydroorotate dehydrogenase (HsDHODH) has been studied for being a target development of new antineoplasic and antiproliferative drugs. synthetic peptide N-t(DH) represents the N-terminal microdomain this enzyme, responsible anchoring it to inner mitochondrial membrane. Also, is known harbor quinones that are essential catalysis. Here we report structural features peptide/membrane interactions obtained by using CD DEER spectroscopic techniques, both in micelles lipid...