A5111890550- Optical Network Technologies
- Antimicrobial Peptides and Activities
- Parallel Computing and Optimization Techniques
- Advanced Photonic Communication Systems
- Semiconductor Lasers and Optical Devices
- Chemical Synthesis and Analysis
- Biochemical and Structural Characterization
- Photonic and Optical Devices
- Advanced Fiber Laser Technologies
- Distributed and Parallel Computing Systems
- Monoclonal and Polyclonal Antibodies Research
- Logic, programming, and type systems
- Embedded Systems Design Techniques
- Advanced Optical Network Technologies
- Glycosylation and Glycoproteins Research
- Laser-Matter Interactions and Applications
- Antibiotic Resistance in Bacteria
- Advanced Fiber Optic Sensors
- Distributed systems and fault tolerance
- Real-Time Systems Scheduling
- Solid State Laser Technologies
- Formal Methods in Verification
- Photonic Crystal and Fiber Optics
- Click Chemistry and Applications
- Algorithms and Data Compression
University of Copenhagen
2016-2025
University of Otago
2024-2025
Kobe Pharmaceutical University
2018
Ausvet (Australia)
2016
Georgia College & State University
2014
Augusta University
2014
University of Georgia
2014
Rigshospitalet
1981-2014
Charlie Norwood VA Medical Center
2014
Syracuse University
1993-2013
Describes a new programming language for structured of computer operating systems. It extends the sequential Pascal with concurrent tools called processes and monitors. Section I explains these concepts informally by means pictures illustrating hierarchical design simple spooling system. II uses same example to introduce notation. The main contribution Concurrent is extend monitor concept an explicit hierarchy access rights shared data structures that can be stated in program text checked compiler.
A language concept for concurrent processes without common variables is introduced. These communicate and synchronize by means of procedure calls guarded regions. This proposed real-time applications controlled microcomputer networks with distributed storage. The paper gives several examples shows that they include procedures, coroutines, classes, monitors, processes, semaphores, buffers, path expressions, input/output as special cases.
This paper describes the philosophy and structure of a multi-programming system that can be extended with hierarchy operating systems to suit diverse requirements program scheduling resource allocation. The nucleus simulates an environment in which execution input/output are handled uniformly as parallel, cooperating processes. A fundamental set primitives allows dynamic creation control processes well communication among them.
The use of non-standard toxicity models is a hurdle in the early development antimicrobial peptides towards clinical applications. Herein we report an extensive vitro and vivo study library 24 peptide-based antimicrobials with narrow spectrum activity veterinary pathogens. haemolytic compounds was evaluated against four different species relative sensitivity highest for canine erythrocytes, intermediate rat human cells lowest bovine cells. Selected were additionally HeLa, HaCaT HepG2 which...
This paper presents a proposal for structured representation of multiprogramming in high level language. The notation used explicitly associates data structure shared by concurrent processes with operations defined on it. clarifies the meaning programs and permits large class time-dependent errors to be caught at compile time. A combination critical regions event variables enables programmer control scheduling resources among competing any degree desired. These concepts are sufficiently safe...
The properties and fiber dependence of distributed Raman pre-amplifiers and, in particular, the effects Rayleigh backscattering, which limits sensitivity improvements that can be realized, is discussed. Bit-error-rate (BER) measurements show In effective receiver 6.2 7.0 dB for dispersion shifted (DSF) silica-core (SCF), respectively. Theoretical predictions noise figure based on measured parameters indicate 6.6 DSF 7.4 SCF good agreement with optical SNR. optimum obtained less than 600 mW...
Abstract Antimicrobial peptides have attracted considerable interest as potential new class of antibiotics against multi-drug resistant bacteria. However, their therapeutic is limited, in part due to susceptibility towards enzymatic degradation and low bioavailability. Peptoids (oligomers N -substituted glycines) demonstrate proteolytic stability better bioavailability than corresponding while many cases retaining antibacterial activity. In this study, we synthesized a library 36 peptoids...
We have investigated the vaccine potential of two peptides derived from 6-kDa early secretory antigenic target (ESAT)-6 antigen in mouse model tuberculosis. The were both strongly immunogenic B6CBAF1 (H-2b,k) mice and primed recall responses same intensity after immunization. However, tuberculosis infection immunization with ESAT-6 resulted focused towards ESAT-61 – 20. Multiple peptide constructs as well free emulsified dimethyl dioctadecylammonium bromide / monophosphoryl lipid A IL-2...
CD4 T cells are crucial to the control of Mycobacterium tuberculosis infection and a key component current vaccine strategies. Conversely, immune-mediated pathology drives disease, recent evidence suggests that adaptive innate responses evolutionarily beneficial M. tuberculosis. We compare functionality cell mounted against dominant cryptic epitopes 6-kDa early secreted Ag (ESAT-6) before postinfection. Protective not targeted during natural were induced by vaccinating mice with truncated...
Antimicrobial peptides (AMPs) are promising candidates for battling multiresistant bacteria. Despite extensive research, structure-activity relationships of AMPs not fully understood, and there is a lack structural data relating to in lipids. Here we present the NMR structure anoplin (GLLKRIKTLL-NH2 ) micellar environment. A vast library substitutions was designed tested antimicrobial hemolytic activity, as well changes lipid interactions. This showed that improvement activity without...
ABSTRACT Immune evasion by Lyme spirochetes is a multifactorial process involving numerous mechanisms. The OspE protein family undergoes antigenic variation during infection and binds factor H (fH) possibly FHL-1/reconectin. In Borrelia burgdorferi B31MI, the consists of three paralogs: BBL39 (ErpA), BBP38, BBN38 (ErpP). BBP38 are identical therefore referred to here as BBL39. goals this study were assess specificity antibody (Ab) response paralogs identify domains or determinants that...
Raman amplification is added to a transmission system provide an increase in power budget allowing for four-fold upgrade capacity either by TDM or WDM. Here, from 2.5 10 Gb/s and WDM single 10-Gb/s channel four channels of each were experimentally verified with improvement the 7.4 dB. gain attractive method installed systems requiring no changes fiber span.
ABSTRACT Fluorescent probes are widely used in cellular imaging and disease diagnosis. Acting as substitute carriers, fluorescent can also be to help transport drugs within cells. In this study, commonly fluorophores, TAMRA (5‐carboxytetramethylrhodamine), PBA (1‐pyrenebutyric acid), NBD (nitrobenzoxadiazole), OG (Oregon Green), CF (5‐carboxyfluorescein) were conjugated with the dipeptide β‐Ala‐Lys, peptide moiety of well‐established transporter substrate β‐Ala‐Lys(AMCA) (AMCA:...