Shichu Liang

ORCID: 0000-0002-9166-646X
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About
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Research Areas
  • Cardiac Imaging and Diagnostics
  • Coronary Interventions and Diagnostics
  • Cardiovascular Function and Risk Factors
  • Venous Thromboembolism Diagnosis and Management
  • Atrial Fibrillation Management and Outcomes
  • Parathyroid Disorders and Treatments
  • Chemotherapy-induced cardiotoxicity and mitigation
  • Acute Myocardial Infarction Research
  • Lipoproteins and Cardiovascular Health
  • Amyloidosis: Diagnosis, Treatment, Outcomes
  • Cardiac tumors and thrombi
  • Mechanical Circulatory Support Devices
  • Peptidase Inhibition and Analysis
  • Advanced MRI Techniques and Applications
  • MRI in cancer diagnosis
  • Aortic Thrombus and Embolism
  • Medical Imaging and Pathology Studies
  • Lysosomal Storage Disorders Research
  • Pharmaceutical Economics and Policy
  • Histiocytic Disorders and Treatments
  • Vasculitis and related conditions
  • Kidney Stones and Urolithiasis Treatments
  • Antiplatelet Therapy and Cardiovascular Diseases
  • Ultrasound and Hyperthermia Applications
  • Signaling Pathways in Disease

Sichuan University
2021-2025

West China Hospital of Sichuan University
2021-2025

Lanzhou University
2024

Lanzhou University Second Hospital
2024

West China Second University Hospital of Sichuan University
2024

Wuhan Union Hospital
2021

Huazhong University of Science and Technology
2021

The Sixth People's Hospital of Shenyang
2021

Union Hospital
2021

Anhui Medical University
2020

Hemodynamic force (HDF) from cardiac MRI can indicate subclinical myocardial dysfunction, and help identify early changes in patients with Fabry disease (FD). The hemodynamic change FD remains unclear. To explore HDF the potential of measurements as diagnostic markers indicating FD. Single-center, prospective, observational study. Forty-six (age: 38 ± 12, females: 45.65%) 46 sex- age-matched healthy controls (HCs). 3 T, including steady-state free precession cine imaging (during multiple...

10.1002/jmri.29700 article EN Journal of Magnetic Resonance Imaging 2025-01-22

Abstract Background Primary pulmonary artery sarcoma (PAS) is an extremely rare malignant tumor with a poor prognosis. The clinical manifestations of PAS are diverse, including dyspnea, chest pain, cough, and hemoptysis. prognosis often due to delayed diagnosis caused by similarity in imaging findings thromboembolism (PTE). These cues include the “wall eclipsing sign”, lobulated bulging margins, gadolinium enhancement during MRI imaging, FDG uptake PET/CT imaging. However, there still many...

10.1186/s12959-023-00578-0 article EN cc-by Thrombosis Journal 2024-01-04

Abstract Background Cancer therapy‐related cardiovascular toxicity (CTR‐CVT) is a major contributor to poor prognosis in breast cancer (BC) patients undergoing chemotherapy. Left ventricular global longitudinal strain (LV GLS) has predictive value for CTR‐CVT, while few researchers take into account late‐onset CTR‐CVT. This study sought provide guide the prediction of CTR‐CVT primary BC over 2 years follow‐up via and contrast‐enhanced echocardiography. Methods Anthracycline anthracycline +...

10.1002/cam4.6039 article EN cc-by Cancer Medicine 2023-05-15

Over one-half of patients with multiple myeloma (MM) die heart failure or arrhythmia. Left ventricular ejection fraction (LVEF) is used to describe left systolic function. However, depressed LVEF means advanced stage dysfunction in MM. pressure-strain-derived myocardial work (LVMW) a novel and noninvasive method for evaluating LV function related dynamic pressure load. MW assessed by index (LVMWI), constructive work, wasted efficiency (LVMWE). In this study, we aimed investigate the value...

10.3389/fcvm.2021.782580 article EN cc-by Frontiers in Cardiovascular Medicine 2022-01-20

Background Acute myocardial infarction (AMI) can lead to sudden cardiac death after prolonged ischemia or heart failure (HF) and impaired left ventricular pump function. However, the underlying mechanism remains largely unknown. The purpose of this study was investigate role mitofilin in alleviating AMI. Methods Recombinant adenoviral vectors for overexpression knockdown were constructed, respectively. A mouse AMI model established effect on pyroptosis examined by detecting lactate...

10.3389/fcvm.2022.823591 article EN cc-by Frontiers in Cardiovascular Medicine 2022-05-02

Abstract Background Left ventricular global longitudinal strain (GLS) obtained from two-dimensional speckle-tracking echocardiography (2D-STE) can reflect cancer therapy-related cardiac dysfunction in breast (BC) patients, however, the accuracy and reproducibility of 2D-STE are restricted due to poor image quality. Methods Between January 2019 October 2021, 160 consecutive BC patients aged ≥ 18 years were recruited. The (mean age: 48.41 ± 9.93 years, 100% women) underwent both...

10.1186/s12947-023-00304-w article EN cc-by Cardiovascular Ultrasound 2023-04-20

Homozygous familial hypercholesterolemia (HoFH), is a rare genetic disorder characterized by dual mutations in the low-density lipoprotein receptor (LDLR) gene, leading to dysfunctional or absent LDLRs, often accompanied severe premature Atherosclerotic Cardiovascular Disease (ASCVD) and exhibiting refractoriness aggressive pharmacological interventions. Double filtration plasmapheresis (DFPP), form of apheresis (LA), has been effectively utilized as an adjunctive treatment modality reduce...

10.1186/s12959-024-00657-w article EN cc-by-nc-nd Thrombosis Journal 2024-10-03

Abstract Background Primary percutaneous coronary intervention (PPCI) is the standard procedure for reperfusion ST-segment elevation myocardial infarction (STEMI), but occurrence of no-reflow phenomenon remains common and associated with adverse outcomes. Aims This study aimed to evaluate whether prolonged balloon inflation in stent deployment would lessen PPCI compared conventional rapid inflation/deflation strategy. Methods Patients were randomly assigned either group (PBSG) or strategy...

10.1186/s12872-022-02477-0 article EN cc-by BMC Cardiovascular Disorders 2022-02-04

The value of cardiovascular magnetic resonance (CMR) in assessing and predicting acute right ventricular (RV) dysfunction patients with anterior ST-segment elevation myocardial infarction (STEMI) remains ascertained. Eighty eight STEMI were prospectively recruited underwent CMR examinations within one week following the coronary intervention. Patients RV ejection fraction (RVEF) less than 2 standard deviations below average at center (RVEF ≤ 45.0%) defined as having dysfunction. size...

10.1007/s10554-024-03166-z article EN cc-by The International Journal of Cardiovascular Imaging 2024-07-22

<title>Abstract</title> Homozygous familial hypercholesterolemia (HoFH), is a rare genetic disorder characterized by dual mutations in the low-density lipoprotein receptor (LDLR) gene, leading to dysfunctional or absent LDLRs, often accompanied severe premature Atherosclerotic Cardiovascular Disease (ASCVD) and exhibiting refractoriness aggressive pharmacological interventions. Double filtration plasmapheresis (DFPP), form of apheresis (LA), has been effectively utilized as an adjunctive...

10.21203/rs.3.rs-4662053/v1 preprint EN cc-by Research Square (Research Square) 2024-07-29

10.1161/circimaging.123.016399 article EN Circulation Cardiovascular Imaging 2024-08-01

Pulmonary embolism (PE) typically presents with chest pain, tachypnea, hemoptysis, syncope, and increased markers of myocardial injury. On an electrocardiogram (ECG), sinus tachycardia, right bundle branch block (RBBB), S1Q3T3 pattern, and/or precordial T-wave inversion may be observed. Despite being one the common causes a third-degree atrioventricular (III° AVB) is rare in cases PE, which can lead to difficulties diagnosis or even overlooking this condition.In case report, we present...

10.3389/fcvm.2023.1013727 article EN cc-by Frontiers in Cardiovascular Medicine 2023-08-08
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