A5000748802- Biochemical Analysis and Sensing Techniques
- Diet and metabolism studies
- Olfactory and Sensory Function Studies
- Obesity, Physical Activity, Diet
- Advanced Chemical Sensor Technologies
- Eating Disorders and Behaviors
- Nutritional Studies and Diet
- Stress Responses and Cortisol
- Diabetes Treatment and Management
- Pain Mechanisms and Treatments
- Sensory Analysis and Statistical Methods
- Diabetes Management and Research
- Vagus Nerve Stimulation Research
- Parkinson's Disease Mechanisms and Treatments
- Diabetes and associated disorders
- Obesity and Health Practices
- Consumer Attitudes and Food Labeling
- Adipose Tissue and Metabolism
- Bipolar Disorder and Treatment
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Health Promotion and Cardiovascular Prevention
- Long-Term Effects of COVID-19
- Botulinum Toxin and Related Neurological Disorders
- Diabetic Foot Ulcer Assessment and Management
- Nutrition, Genetics, and Disease
University Hospital Leipzig
2019-2025
Leipzig University
2024
Helmholtz Centre for Environmental Research
2023
Deutsches Diabetes-Zentrum e.V.
2015-2016
Heinrich Heine University Düsseldorf
2016
German Center for Diabetes Research
2016
TU Dresden
2012
University of California, San Francisco
2010
<h3>Objective</h3> Cardiovascular autonomic neuropathy is a common but underestimated diabetes-related disorder. Associations between cardiovascular dysfunction and subclinical inflammation, both risk factors of diabetic comorbidities mortality, have been proposed in non-diabetic populations, while data for type 1 2 diabetes are conflicting. Our aim was to investigate associations inflammation-related biomarkers cardiac patients with diabetes. <h3>Methods</h3> We characterised the seven...
Abstract Background Obesity is a multifactorial disease reaching pandemic proportions with increasing healthcare costs, advocating the development of better prevention and treatment strategies. Previous research indicates that gut microbiome plays an important role in metabolic, hormonal, neuronal cross-talk underlying eating behavior. We therefore aim to examine effects prebiotic neurocognitive behavioral interventions on food decision-making assay mechanisms Randomized Controlled Trial...
Objective Subclinical inflammation has been implicated in the development of diabetic sensorimotor polyneuropathy (DSPN), but studies using electrophysiological assessment as outcomes are scarce. Therefore, we aimed to investigate associations biomarkers reflecting different aspects subclinical with motor and sensory nerve conduction velocity (NCV) individuals diabetes. Design methods Motor NCV was assessed recently diagnosed type 2 ( n =352) or 1 diabetes =161) from baseline cohort...
Abstract Aims Taste modifies eating behaviour, impacting body weight and potentially obesity development. The Obese Bud (OTB) Study is a prospective cohort study launched in 2020 at the University of Leipzig Obesity Centre cooperation with HI‐MAG Institute. OTB will test hypothesis that taste cell homeostasis perception are linked to obesity. Here, we provide design, data collection process baseline characteristics. Materials Methods Participants presenting overweight, or normal undergo...
Fibroblast growth factor 21 (FGF21) is a regulator of addictive behavior. Increasing evidence suggests an impact FGF21 on eating behavior, food and drug cravings other adipokines like insulin-like 1 (IGF-1) or adiponectin. We investigated the association serum genetic variants with aspects craving obesity related metabolic parameters including adipokine levels. Standardized questionnaires, blood samples anthropometric data Sorbs cohort (n = 1046) were analyzed using SPSS. For analyses,...
The computerized Leeds Food Preference Questionnaire measures liking and wanting for food images as separable components of reward. We aimed to validate a German version this instrument (LFPQ-G). LFPQ-G-development included standardized production culturally adapted representing four categories varying in fat (high vs. low) taste (sweet savory). LFPQ-G was validated 59 mostly female (69.5 %), on average normal weight participants with median BMI 23.2 kg/m2 [21.3 kg/m2; 26.3 kg/m2], aged...
<title>Abstract</title> <bold>Background: </bold>Obesity is a multifactorial disease reaching pandemic proportions with increasing healthcare costs, advocating the development of better prevention and treatment strategies. Previous research indicates that gut microbiome plays an important role in metabolic, hormonal, neuronal cross-talk underlying eating behavior. We therefore aim to examine effects prebiotic neurocognitive behavioral interventions on food decision-making assay mechanisms...
Sweet and salty tastes are highly palatable drive food consumption potentially uncontrolled eating, but it remains unresolved whether the ability to recognize sweet affects reward eating. We investigate association of taste recognition with liking wanting Thirty-eight, mainly female (68%) participants Obese Taste Bud study, between 22 67 years old, a median BMI 25.74 kg/m2 (interquartile range: 9.78 kg/m2) completed test, Leeds Food Preference Questionnaire assess reward, Power Scale (PFS)...
Saliva is essential for the proper dilution and distribution of taste molecules on tongue. It harbors extracellular vesicles (EVs), which mediate cell-cell communication. Changes in composition salivary EVs may arise under obese conditions potentially be involved sensation dysregulated eating behavior. Therefore, this study addresses relationship between size concentration metabolic shifts obesity or factors sensation. A total 119 participants Obese Taste Bud (OTB) Study were included, who...
Objective: Biomarkers of subclinical inflammation are associated with distal sensorimotor polyneuropathy, but their relationship to objective electrophysiological measures has not been assessed. Therefore, the aim this study was investigate associations between inflammation-related biomarkers and nerve conduction velocity (NCV) in German Diabetes Study (GDS).