A5001543256- Gut microbiota and health
- Analytical Chemistry and Chromatography
- Natural Compound Pharmacology Studies
- Dietary Effects on Health
- Metabolomics and Mass Spectrometry Studies
- Inflammatory Biomarkers in Disease Prognosis
- Electrochemical sensors and biosensors
- Pregnancy-related medical research
- Phytochemicals and Antioxidant Activities
- Heart Rate Variability and Autonomic Control
- Analytical Chemistry and Sensors
- Immune cells in cancer
- Thermoregulation and physiological responses
- Mangiferin and Mango Extracts
- Eicosanoids and Hypertension Pharmacology
- Tryptophan and brain disorders
- Cardiovascular and exercise physiology
Singapore University of Technology and Design
2022-2024
Agency for Science, Technology and Research
2024
The mangosteen (Garcinia mangostana L.) pericarp is known to be rich in potent bioactive phytochemical compounds such as xanthones, which possess pharmacologically important antioxidant activity and beneficial cardiometabolic properties. Mangosteen typically classified unavoidable food waste discarded, despite being that therefore present an exciting opportunity for valorization. Thus, this study aims extract from using pressurized hot water extraction (PHWE) determine its biological effects...
Endothelial dysfunction is a critical initiating factor contributing to cardiovascular diseases, involving the gut microbiome-derived metabolite trimethylamine N-oxide (TMAO). This study aims clarify time-dependent molecular pathways by which TMAO mediates endothelial through transcriptomics and metabolomics analyses in human microvascular cells (HMEC-1). Cell viability reactive oxygen species (ROS) generation were also evaluated. treatment for either 24H or 48H induces reduced cell enhanced...
We proposed a simple method for ratiometrically detecting the ethanol content in aqueous solutions using low-cost and commercially available dye – acridine.
This research paper investigates the effectiveness of a virtual reality (VR) game-based intervention using real-time biofeedback for stress management and performance among fire-fighting trainees from Singapore Civil Defence Force (SCDF). Forty-seven were enrolled in this study randomly assigned into three groups: control, placebo, intervention. The participants’ physiological responses, psychological training performances evaluated during specific times over standard 22-week regimen....
Cardiovascular diseases (CVD) are the principal cause of death worldwide. Endothelial dysfunction is recognized as a crucial initiating contributing factor for CVD. Trimethylamine–N–oxide (TMAO), gut microbiome-derived metabolite involved in CVD progression. However, underlying time-dependent molecular mechanisms resulting pathogenesis TMAO endothelial cells remain unclear. To investigate signatures TMAO-induced human microvascular (HMEC–1), we performed transcriptomics and metabolomics...