A5047369484- Microfluidic and Capillary Electrophoresis Applications
- Analytical Chemistry and Sensors
- Advanced Sensor and Energy Harvesting Materials
- 3D Printing in Biomedical Research
- Electrowetting and Microfluidic Technologies
- Innovative Microfluidic and Catalytic Techniques Innovation
- Neuroscience and Neural Engineering
- Biosensors and Analytical Detection
- Conducting polymers and applications
- Ionic liquids properties and applications
- Advanced Chemical Sensor Technologies
- Water Quality Monitoring and Analysis
- Advanced biosensing and bioanalysis techniques
- Bone Tissue Engineering Materials
- Hydrogels: synthesis, properties, applications
- Molecular Communication and Nanonetworks
- Surface Modification and Superhydrophobicity
- Inhalation and Respiratory Drug Delivery
- Electrospun Nanofibers in Biomedical Applications
- Immunotherapy and Immune Responses
- Lipid Membrane Structure and Behavior
- Analytical Methods in Pharmaceuticals
- Water Quality Monitoring Technologies
- Electrohydrodynamics and Fluid Dynamics
- Protein purification and stability
Ikerbasque
2021-2023
University of the Basque Country
2013-2023
BioCruces Health research Institute
2023
University of Cambridge
2019-2023
Addenbrooke's Hospital
2023
Dublin City University
2015
MicroLIQUID (Spain)
2015
Abstract 3D cell culture formats more closely resemble tissue architecture complexity than 2D systems, which are lacking most of the cell–cell and cell–microenvironment interactions in vivo milieu. Scaffold‐based systems integrating natural biomaterials extensively employed engineering to improve survival outgrowth, by providing chemical physical cues extracellular matrix (ECM). Using freeze–drying technique, porous composite scaffolds consisting poly(3,4‐ethylene‐dioxythiophene) doped with...
Nowadays, miniaturization and portability are crucial characteristics that need to be considered for the development of water monitoring systems. In particular, use handheld technology, including microfluidics, is exponentially expanding due its versatility, reduction reagents minimization waste, fast analysis times portability. Here, a hybrid miniaturized polymer platform with paper-based microfluidic device was developed simultaneous detection nitrite nitrate in real samples from both,...
Abstract Cell membranes are fundamental for cellular function as they protect the cell and control passage in out of cell. Despite their clear significance, often difficult to study, due complexity lack available technologies interface with them transduce functions. Overcoming this by developing simple, reductionist models can facilitate study. Indeed, lipid layers represent a simplified yet representative model membrane. Lipid highly insulating, property that is directly affected changes...
Three-dimensional in vitro stem cell models have enabled a fundamental understanding of cues that direct fate. While sophisticated 3D tissues can be generated, technology accurately monitor these complex high-throughput and non-invasive manner is not well adapted. Here we show the development bioelectronic devices based on electroactive polymer poly(3,4-ethylenedioxythiophene)-poly(styrenesulfonate)-(PEDOT:PSS) their use for non-invasive, electrical monitoring growth. We electrical,...
Conducting polymers such as PEDOT have attracted considerable attention in the tissue engineering field to add an active electrical read-out 3D cell cultures. However, is normally copolymerized with PSS− that possibly degrades acidic by-products long-term. Given this drawback, it preferable tailor PEDOT:polyelectrolyte dispersions better meet morphological and physiological microenvironment of human tissues. Herein, a novel bioelectrical interface shape porous scaffold made conducting...
An in-house Iterative Multivariate Standard Addition Method has been developed for the turbidimetric determination of sulphate in seawater.
Air liquid interfaced (ALI) epithelial barriers are essential for homeostatic functions such as nutrient transport and immunological protection. Dysfunction of implicated in a variety autoimmune inflammatory disorders and, such, sensors capable monitoring barrier health integral disease modelling, diagnostics drug screening applications. To date, gold-standard electrical methods detecting resistance require rigid electrodes bathed an electrolyte, which limits compatibility with biological...
The increment of uncontrolled nutrients concentration in water is the subject increasing environmental concern. In particular, nitrate causes eutrophication algae, leading to fauna and flora demise.[1] order favour an easy adequate monitoring this problem, we have developed ionogel-based sensor for colorimetric determination image analysis detection nitrite water. consists on a small poly(methyl)methacrilate (PMMA) device cut by CO2 laser where both calibration zones are integrated. A simple...
The increment of uncontrolled nitrate concentration in water could lead to an environmental disaster. In order favour easy and adequate monitoring this problem, we have developed ionogel-based sensor for the colorimetric determination image analysis detection at point need.
Non-invasive collection of target cells is crucial for research in biology and medicine. In this work, we combine a thermo-responsive material, poly(N-isopropylacrylamide), with an electroactive poly(3,4-ethylene-dioxythiopene):poly(styrene sulfonate), to generate smart conductive copolymer the label-free non-invasive detection capture release on gold electrodes by electrochemical impedance spectroscopy. The functionalized fibronectin tumor cells, undergoes conformational change response...
This contribution describes for the first time fabrication and performance of a reversible ionogel microvalve in-situ photopolymerised into reusable disc platform fluid control. During storage spinning, swollen provides permanent liquid barrier due to special chemical characteristics ionogel. The is easy actuated using white light LED allowing open channel at desired time. actuation mechanism chemically when an acid solution provided microvalve. Here perpendicular microchannel, connected...
This abstract describes for the first time use of alginate hydrogels as miniaturised valves in microfluidic devices. These biocompatible and biodegradable microvalves are in-situ generated, on demand, allowing flow control. The devices were fabricated using origami technique with seven layers cyclic olefin copolymer (COP) thermocompression bonding. They can be thermally actuated (ON/OFF) at mild temperatures, 37 °C, chemically erased from main channel an ethylenediaminetetraacetic acid...