A5101843577- SARS-CoV-2 and COVID-19 Research
- COVID-19 Clinical Research Studies
- Respiratory viral infections research
- Ubiquitin and proteasome pathways
- Prostate Cancer Treatment and Research
- Air Quality and Health Impacts
- COVID-19 Impact on Reproduction
- Phytochemicals and Antioxidant Activities
- Heavy Metal Exposure and Toxicity
- Energy and Environment Impacts
- Food Chemistry and Fat Analysis
- Natural product bioactivities and synthesis
- Advanced Chemical Sensor Technologies
- interferon and immune responses
- Estrogen and related hormone effects
- Mitochondrial Function and Pathology
- Occupational exposure and asthma
- Diphtheria, Corynebacterium, and Tetanus
- Analytical Chemistry and Sensors
- Protein Hydrolysis and Bioactive Peptides
- Veterinary Equine Medical Research
- Textile materials and evaluations
- Edible Oils Quality and Analysis
- Mercury impact and mitigation studies
- Protein Degradation and Inhibitors
Inner Mongolia Agricultural University
2022-2025
Addenbrooke's Hospital
2021-2023
University of Cambridge
2021-2023
Ikerbasque
2023
Jilin Agricultural University
2022
Huazhong University of Science and Technology
2019
Newcastle University
2015
Centers for Disease Control and Prevention
2004
Abstract Background Flunixin meglumine (FM) is commonly used in painful conditions horses; however, it may contribute to equine gastric ulcer syndrome (EGUS). Some veterinarians combine omeprazole (OME) and FM reduce EGUS risk. However, the efficacy safety of this combination Mongolian horses with chronic lameness remain unknown. Objectives To investigate changes scores through comparison three treatment strategies: FM, + OME placebo treated control (CON) assess effects these treatments on...
Biogenic amines (BAs) are widely contained in fermented meat products and harmful to human health with high level content. Reducing BAs content microorganisms that don't produce decarboxylase seems beneficial. This study screened three strains had the capacity degrade from different regions of Inner Mongolia. Three were because they didn't have amino acid activity good growth performance abilities producing, salt resistance antibacterial. X22-2 HX2-1 identified as Lactiplantibacillus...
The persistence of androgen receptor (AR) signalling in castrate-resistant prostate cancer (CRPC) highlights the unmet clinical need for development more effective AR targeting therapies. A key mechanism therapy-resistance is by selection mutations that convert anti-androgens to agonists enabling retention androgenic CRPC. To improve our understanding these receptors advanced disease we developed a physiologically-relevant model analyse global functionality mutants Using...
There are limited effective prophylactic/early treatments for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Viral entry requires spike protein binding to the angiotensin-converting enzyme-2 receptor and cleavage by transmembrane serine protease (TMPRSS2), a cell surface protease. Targeting of TMPRSS2 either androgen blockade or direct inhibition is in clinical trials early SARS-CoV-2
The objective of this study was to investigate the effects sheep slaughter age on myogenic characteristics in skeletal muscle satellite cells (SMSCs).Primary SMSCs were isolated from hind leg biceps femoris muscles Wurank lambs (slaughtered at three months, Mth-3) and adults fifteen Mth-15). selected by morphological observation fluorescence staining. Myogenic regulatory factors (MRF) myosin heavy chain (MyHC) expressions analyzed days 1, 3, 4, 5.The factor 5 (Myf5), differentiation (MyoD),...
Anthocyanins have great health benefits, especially malvidin. Vitis amurensis Rupr are rich in malvidin, and malvidin-3-O-glucoside (Mv3G) monomer is the most abundant. However, natural anthocyanins unstable, which limits their wide application food field. Soybean insoluble dietary fiber (SIDF) has high stability, it can be used as an inert substrate to construct a stable system, may improve stability of anthocyanins. The optimal condition system SIDF Mv3G at pH 3.0 was determined by...
BackgroundCigarette smoking has many serious negative health consequences. The relationship between and SARS-CoV-2 infection is controversial, specifically whether smokers are at increased risk of infection. We investigated the impact cigarette smoke on ACE2 isoform expression in differentiated primary human bronchial epithelial cells air-liquid-interface (ALI). assessed response to CSE therapeutics reported modulate ACE2. exposed ALI cultures extract (CSE) then infected them with...
Air liquid interfaced (ALI) epithelial barriers are essential for homeostatic functions such as nutrient transport and immunological protection. Dysfunction of implicated in a variety autoimmune inflammatory disorders and, such, sensors capable monitoring barrier health integral disease modelling, diagnostics drug screening applications. To date, gold-standard electrical methods detecting resistance require rigid electrodes bathed an electrolyte, which limits compatibility with biological...
Quantitative proteomics is able to provide a comprehensive, unbiased description of changes cells caused by viral infection, but interpretation may be complicated differential in infected and uninfected 'bystander' cells, or the use non-physiological cellular models.
The stems of Cynomorium songaricum are used in traditional Chinese medicine as a tonic and also locally food material livestock feed. It is known that some the falvan-3-ol monomers dimers entered milk dairy sheep fed with C. biotransformation products original flavan-3-ol polymers stems. This study was performed to investigate process flavan-3-ols evaluate bioactivities. results showed procyanidin A2 epicatechin could be released from polymeric through rumen microbial metabolism. On...
Abstract Background There are limited effective prophylactic treatments for SARS-CoV-2 infection, and early treatment options. Viral cell entry requires spike protein binding to the ACE2 receptor cleavage by TMPRSS2, a surface serine protease. Targeting of TMPRSS2 either androgen blockade or direct inhibition is already in clinical trials infection. Methods The likely initial cells ciliated upper airway. We therefore used differentiated primary human airway epithelial maintained at...
TPS 683: Short-term health effects of air pollutants 2, Exhibition Hall, Ground floor, August 28, 2019, 3:00 PM - 4:30 Background: The association personal exposure to fine particulate matter (PM2.5) with pulmonary in children is still largely unknown. We aimed investigate the short-term PM2.5 on various lung function outcomes among healthy Chinese during their normal activities. Methods: A longitudinal panel study was performed 282 aged 4-13 years from different schools urban (Wuhan) and...
TPS 683: Short-term health effects of air pollutants 2, Exhibition Hall, Ground floor, August 28, 2019, 3:00 PM - 4:30 Background: Little is known if fine particulate matter (PM2.5) has an influence on renal function in Children. Objective: To investigate the association between short-term PM2.5 exposure and among healthy Chinese children. Methods: We conducted a longitudinal panel study 137 children from two kindergartens middle school Wuhan, China with up to 3 repeated visits across...
Searchable abstracts of presentations at key conferences in endocrinology ISSN 1470-3947 (print) | 1479-6848 (online)
Cigarette smoking has many serious negative health consequences. The relationship between and SARS-CoV-2 infection is controversial, specifically whether smokers are at increased risk of infection. We investigated the impact cigarette smoke on ACE2 isoform expression in differentiated primary human bronchial epithelial cells air-liquid-interface (ALI). assessed response to CSE therapeutics reported modulate ACE2. exposed ALI cultures extract (CSE) then infected them with SARS-CoV-2. measured...