Stefano Spinaci

ORCID: 0000-0002-9255-534X
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About
Contact & Profiles
Research Areas
  • Reproductive Biology and Fertility
  • Cancer Risks and Factors
  • Breast Cancer Treatment Studies
  • Lymphatic System and Diseases
  • Ovarian function and disorders
  • Lymphatic Disorders and Treatments
  • Breast Implant and Reconstruction
  • Ovarian cancer diagnosis and treatment
  • Chronic Obstructive Pulmonary Disease (COPD) Research
  • Breast Lesions and Carcinomas
  • Estrogen and related hormone effects
  • Inhalation and Respiratory Drug Delivery
  • Gastrointestinal disorders and treatments
  • Vascular Malformations and Hemangiomas
  • BRCA gene mutations in cancer
  • HER2/EGFR in Cancer Research
  • Respiratory Support and Mechanisms
  • Cancer and Skin Lesions
  • Lung Cancer Diagnosis and Treatment
  • Nail Diseases and Treatments
  • Cutaneous Melanoma Detection and Management
  • Global Cancer Incidence and Screening
  • Asthma and respiratory diseases
  • Growth Hormone and Insulin-like Growth Factors
  • Reconstructive Surgery and Microvascular Techniques

Villa Torri Hospital
2023

University of Genoa
2013-2022

Centro Ricerche FIAT
2020-2022

Ospedale Policlinico San Martino
2012-2022

Lymphatic Education & Research Network
2012-2017

Istituti di Ricovero e Cura a Carattere Scientifico
2012-2016

Women's General Hospital
2012

Santen (Japan)
2012

University of Pavia
2012

Adamis Pharmaceuticals (United States)
2012

Breast cancer-related lymphedema (LE) represents an important morbidity that jeopardizes breast cancer patients' quality of life. Different attempts to prevent LE brought about improvements in the incidence pathology but still a frequent occurrence survivors. Over 4 years ago, Lymphatic Microsurgical Preventing Healing Approach (LYMPHA) was proposed and long-term results are reported this study. From July 2008 December 2012, 74 patients underwent axillary nodal dissection for treatment...

10.1002/micr.22254 article EN Microsurgery 2014-03-26

The effects of inhaled MgSO 4 on histamine bronchoprovocation test (BPT) were studied in nine asthmatics clinical remission (FEV 1 > 80% predicted). Patients performed BPT 2 separate days, one day after saline and the other inhalation, a randomized double‐blind design. Spirometry flow/volume curve recorded each before 5 min NaCl or . No significant difference was observed lung function measurements days either dose which produced 20% decrease control FEV (PD 20 ) significantly increased...

10.1111/j.1398-9995.1987.tb02198.x article EN Allergy 1987-04-01

Breast cancer (BC) is the most common malignancy among women. Among 5%–10% of diagnoses are correlated with hereditary syndromes, while remaining cases sporadic and linked to multiple factors. When a pathogenetic variant in one genes commonly associated BC detected, patient referred tailored surveillance program; otherwise, standard follow-up guidelines applied. We present unique case diagnosed two monozygotic twins at same age apparently unrelated syndrome known date. Notably, despite...

10.1177/17588359241297565 article EN cc-by-nc Therapeutic Advances in Medical Oncology 2025-01-01

Groin lymphocele (GL) is a frequent complication of inguinal lymph node dissection, and conservative treatment not always successful. Different surgical methods have been used to treat lymphoceles arising from lymphatics injured during groin surgery. However, they all involve the closure merging at lymphocele, increasing risk postoperative lower limb lymphedema or worsening if already clinically evident. We assessed efficacy diagnostic therapeutic protocol manage using lymphoscintigraphy...

10.1002/micr.22129 article EN Microsurgery 2013-07-11

In a 3-arm presurgical trial, four-six weeks exemestane 25 mg three times/week (TIW) was non-inferior to mg/day (QD) in suppressing circulating estradiol postmenopausal women with ER-positive breast cancer. Since obesity may decrease efficacy, we analyzed changes sex steroids, adipokines, Ki-67, and drug levels relation obesity. Postmenopausal early-stage cancer were randomized either QD (n = 57), TIW or mg/week (QW, n 62) for 4-6 before surgery. Serum tissue pre- post-treatment biomarkers...

10.1038/s41523-024-00616-8 article EN cc-by npj Breast Cancer 2024-01-18
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