Seung-Jin Kwag

ORCID: 0000-0002-9267-9158
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About
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Research Areas
  • Gastric Cancer Management and Outcomes
  • Gastrointestinal Tumor Research and Treatment
  • Metastasis and carcinoma case studies
  • Cancer, Lipids, and Metabolism
  • Colorectal Cancer Surgical Treatments
  • Gastrointestinal disorders and treatments
  • Diverticular Disease and Complications
  • Prostate Cancer Treatment and Research
  • Gallbladder and Bile Duct Disorders
  • Cholangiocarcinoma and Gallbladder Cancer Studies
  • Inflammatory Biomarkers in Disease Prognosis
  • Pediatric Hepatobiliary Diseases and Treatments
  • Cancer, Hypoxia, and Metabolism
  • Esophageal and GI Pathology
  • Breast Cancer Treatment Studies
  • Pancreatic and Hepatic Oncology Research
  • Minimally Invasive Surgical Techniques
  • Radiomics and Machine Learning in Medical Imaging
  • S100 Proteins and Annexins
  • Congenital Anomalies and Fetal Surgery
  • Caveolin-1 and cellular processes
  • Colorectal Cancer Treatments and Studies
  • Abdominal Surgery and Complications
  • Sirtuins and Resveratrol in Medicine
  • Food Quality and Safety Studies

Gyeongsang National University Hospital
2015-2024

Gyeongsang National University
2014-2024

Tea Research Institute
2024

Biomedical Research Institute
2024

Seoul St. Mary's Hospital
2013

Catholic University of Korea
2013

The authors evaluate the prevalence of malnutrition and its effect on postoperative morbidity patients after surgery for colorectal cancer.Three hundred fifty-two were enrolled prospectively. Nutritional risk screening 2002 (NRS 2002) score was calculated through interview with patient admission. Clinical characteristics, tumor status surgical procedure recorded.The at nutritional 28.1 per cent according to NRS 2002. rate complication 27%. There a significant difference in rates between...

10.4174/astr.2014.86.4.206 article EN Annals of Surgical Treatment and Research 2014-01-01

Abstract Background We aimed to identify whether neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte (PLR) are more useful predictors after initial intention treat than at the time of diagnosis. Methods collected medical data 533 patients. The results peripheral blood sampling before primary treatments were labeled as cohort, those obtained between 24 36 months treatment defined 2nd cohort. Delayed metastasis has been distant 2 years treatment, survival outcome was estimated...

10.1186/s12885-020-07700-9 article EN cc-by BMC Cancer 2020-12-01

Breast malignancy remains one of the most common causes cancer‑associated mortalities among women. MicroRNA (miR)‑221 and miR‑222 are homologous miRs have a substantial impact on cancer progression. In present study, regulatory mechanisms miR‑221/222 its target annexin A3 (ANXA3) in breast cells were investigated. tissue samples collected to evaluate expression patterns levels cell lines tissues according clinical characteristics. The increased or decreased compared with normal line subtype....

10.3892/etm.2023.11826 article EN Experimental and Therapeutic Medicine 2023-02-07

Background: Because laparoscopic liver resection (LLR) has a steep learning curve, analyzing experience is important for trainees. Several authors have described the curve of LLR, without comparing curves between major and minor LLR. Methods: Perioperative data were retrieved from medical records 170 consecutive patients who underwent LLR by single surgeon at tertiary hospital. Learning generated compared using cumulative sum control charts moving average. Results: Major was performed in 96...

10.1089/lap.2016.0063 article EN Journal of Laparoendoscopic & Advanced Surgical Techniques 2016-04-27

While extended cholecystectomy is recommended for T2 gallbladder cancer (GBC), the role of hepatic resection GBC unclear. This study aimed to identify necessity in patients with GBC. Data 81 histopathologically proven who underwent surgical between January 1999 and December 2017 were enrolled from a retrospective database. Of these, 36 had peritoneal-side (T2a) tumors 45 hepatic-side (T2b) tumors. To optimal management method, classified into group (n = 44, T2a/T2b 20/24) non-hepatic 37,...

10.1186/s12957-018-1556-6 article EN cc-by World Journal of Surgical Oncology 2019-01-07

Heat shock protein 20 (HSP20), which is a member of the small heat family, known to participate in many pathological processes, such as asthma, intimal hyperplasia, and insulin resistance. However, function HSP20 cancer development not yet fully understood. In this study, we identified down-regulated resected colorectal (CRC) specimens compared with their paired normal tissues. Because proteins were barely detectable HCT-116 cells (a human cell line), recombinant adenovirus encoding...

10.1002/jcb.24966 article EN Journal of Cellular Biochemistry 2014-09-04

A stercoral perforation of the rectum due to a fecaloma is rare disease with high mortality rate. Although multiple case reports colonic perforations have been published, data regarding rectal are limited. This report will highlight one such that was successfully treated laparoscopic operation.

10.3393/ac.2013.29.2.77 article EN cc-by-nc Annals of Coloproctology 2013-01-01

Although laparoscopic treatment for T1 gallbladder cancer (GBC) has been described previously, the differences in oncologic outcomes between and conventional open surgery T2 GBC have not investigated. We aimed to assess role of using retrospectively collected data 81 patients with who underwent surgical resection January 2010 December 2017. Eligible were classified into "laparoscopic" "open" groups. Propensity-score matching was performed a 1:1 ratio. The effects type on oncological After...

10.3390/jcm11092644 article EN Journal of Clinical Medicine 2022-05-08

The Niti CAR 27 (ColonRing) uses compression to create an anastomosis. This study aimed investigate the safety and effectiveness of anastomosis created with in a laparoscopic anterior resection for sigmoid colon cancer.In single-center study, 157 consecutive patients who received operation between March 2010 December 2011 were retrospectively assessed. (CAR group, 63 patients) colorectal anastomoses compared conventional double-stapled (CDS 94 anastomoses. Intraoperative, immediate...

10.3393/ac.2014.30.2.77 article EN cc-by-nc Annals of Coloproctology 2014-01-01

This study evaluated the outcomes and prognostic factors for breast cancer according to initial lymph node (LN) status. Among patients with LN-negative cancer, we also focused on value of estrogen receptor (ER) status.Medical records were retrospectively reviewed 715 who underwent curative surgery between January 2005 December 2015 at a single Korean institution. We that associated metastasis-free survival (MFS) LN status.Among (age: 28-87 years), 458 (64.1%) did not have axillary...

10.1097/md.0000000000025000 article EN cc-by-nc Medicine 2021-03-16

The purpose of the study was to evaluate safety and effectiveness three-port laparoscopic right colectomy (3-LRC) for right-sided colon cancer compared with conventional five-port (5-LRC).One hundred sixty-three patients diagnosed adenocarcinoma underwent (LRC) between April 2011 December 2017. Seventy-four these 3-LRC procedure 89 5-LRC. Clinical characteristics, perioperative short-term outcomes, pathologic data were analyzed.There no differences in TNM stage, tumor location, estimated...

10.1089/lap.2018.0498 article EN Journal of Laparoendoscopic & Advanced Surgical Techniques 2018-09-28

Toxocara canis is an important roundworm of canids and a fearsome animal parasite humans. Human infections can lead to syndromes called visceral larva migrans (VLM), ocular migrans, neurotoxocariasis, covert toxocariasis. VLM most commonly diagnosed in children younger than 8 years age, but adult cases are relatively frequent among those infected by ingesting the raw tissue paratenic hosts East Asia. This research reports case 59-year-old man with sigmoid colon cancer, who visited our...

10.3393/ac.2017.12.20 article EN cc-by-nc Annals of Coloproctology 2018-06-30

This study is to evaluate the perioperative outcomes of duodenojejunostomy (DJ) procedure in pylorus preserving pancreaticoduodenectomy (PPPD).In this study, as noted between 2010 and 2018, there were 77 PPPDs which performed at our hospital by one surgeon. We began circular stapled method from 2014, continue with for aforementioned surgeries including up today. The clinical data collected retrospectively compare two methods, anastomosis hand - sewn anastomosis.There 34 patients a group, 43...

10.14701/ahbps.2019.23.3.245 article EN Annals of Hepato-Biliary-Pancreatic Surgery 2019-01-01

Ectopic opening of the pancreatic and bile ducts (EOPBD) into duodenal bulb is an extremely rare congenital anomaly with unknown clinical implications. We presented a case gallbladder cancer EOPBD bulb. A 57-year-old male was referred to our hospital intermittent right upper abdominal pain. Endoscopic retrograde cholangiopancreatography magnetic resonance showed individual no papillary structure, focal nodular lesion in gallbladder. follow-up computed tomography scan 9 months later revealed...

10.14701/kjhbps.2015.19.3.121 article EN cc-by-nc Korean Journal of Hepato-Biliary-Pancreatic Surgery 2015-01-01

209 Background: Anti-angiogenic agents are important for treating patients with advanced colorectal adenocarcinoma, however, their efficacy is not long-lasting and survival benefits modest. Reliable biomarkers novel targets angiogenesis still required in this era. Angiopoietin-like protein 2 (AGLP-2) an emerging biomarker cardiovascular disease, but its role the oncology area yet to be elucidated. Methods: Serum samples from carcinoma treated bevacizumab-containing chemotherapy were...

10.1200/jco.2024.42.3_suppl.209 article EN Journal of Clinical Oncology 2024-01-20

Abstract Muscle atrophy, a debilitating condition characterized by loss of muscle mass and strength, is major concern in various clinical settings. Acetyl genistin (AG), bioactive compound, was evaluated for its role cell differentiation potential protective effects against dexamethasone (dexa)-induced atrophy. Our study demonstrated that AG significantly promoted C2C12 myotube differentiation, as evidenced enhanced width increased fusion index. Notably, treatment upregulated the expression...

10.1186/s13765-024-00885-8 article EN cc-by Applied Biological Chemistry 2024-03-19

<title>Abstract</title> Background Dysregulated inflammation is a key factor in chronic diseases such as asthma, obstructive pulmonary disease, arthritis, heart and diabetes. This study explores the anti-inflammatory potential of <italic>Vital Air Herb™</italic> (VAH), blend thirteen traditional East Asian medicinal plants, against specific inflammatory disease (e.g., allergy). Methods VAH extracts were prepared by maceration water or ethanol. The IncuCyte® system was used to assess VAH's...

10.21203/rs.3.rs-4303410/v1 preprint EN cc-by Research Square (Research Square) 2024-05-23

Purpose: Several studies demonstrated that obesity and underweight were negatively associated with outcomes of breast cancer. However, the results are still controversial, impact body mass index (BMI) on distant metastasis-free survival (MFS), which might directly affect mortality, was less well evaluated. Our study aimed to verify prognostic effect BMI in cancer.Methods: A retrospective analysis 504 patients stage I-III cancer who underwent surgery from January 2005 December 2013 performed....

10.14216/kjco.23010 article EN cc-by-nc Korean Journal of Clinical Oncology 2023-12-31

Purpose: The aim of this study was to investigate the risk factors reflux associated complications (reflux symptoms, esophagitis, and esophageal stricture) after gastrectomy for proximal gastric cancer. Methods: 150 patients with cancer were included from January 2005 December 2008. Their medical surgical records retrospectively analyzed concerning clinical pathologic characteristics, operation methods, morbidity, nutritional states. Results: Tumor sizes methods statistically significant in...

10.4174/jkss.2010.79.4.246 article EN Journal of the Korean Surgical Society 2010-01-01
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