A5100334432- Aquatic Ecosystems and Phytoplankton Dynamics
- Gut microbiota and health
- Marine and coastal ecosystems
- Pharmaceutical and Antibiotic Environmental Impacts
- Microbial Community Ecology and Physiology
- Spectroscopy Techniques in Biomedical and Chemical Research
- Soil and Water Nutrient Dynamics
- Child Nutrition and Water Access
- Clostridium difficile and Clostridium perfringens research
- Agriculture, Soil, Plant Science
- Biocrusts and Microbial Ecology
- Water Quality and Pollution Assessment
- Vibrio bacteria research studies
- Bacteriophages and microbial interactions
- Retinal Development and Disorders
- Fecal contamination and water quality
- Algal biology and biofuel production
- Muscle Physiology and Disorders
- Exercise and Physiological Responses
- Ecosystem dynamics and resilience
- Smart Materials for Construction
- Plant-Microbe Interactions and Immunity
- Sustainability and Ecological Systems Analysis
- Redox biology and oxidative stress
- Listeria monocytogenes in Food Safety
Pukyong National University
2021-2025
Gangnam Severance Hospital
2025
Yonsei University
2025
Sungkyunkwan University
2016-2024
Gyeongsang National University
2024
The Ohio State University
2014-2023
Hanyang University
2022-2023
Seowon University
2017-2020
Gachon University
2020
Sejong University
2013-2018
A positron emission tomography (PET) tracer composed of (18)F-labeled maltohexaose (MH(18)F) can image bacteria in vivo with a sensitivity and specificity that are orders magnitude higher than those fluorodeoxyglucose ((18)FDG). MH(18)F detect early-stage infections as few 10(5) E. coli colony-forming units (CFUs), identify drug resistance vivo. has the potential to improve diagnosis bacterial given its unique combination high for bacteria.
Early life plays a vital role in the development of gut microbiome and subsequent health. While many factors that shape have been described, including delivery mode, breastfeeding, antibiotic use, household environments is still unclear. Furthermore, antimicrobial resistome its health disease not well characterized, particularly settings with water insecurity less sanitation infrastructure.This study investigated infants young children (ages 4 days-6 years) rural Nicaragua using Oxford...
Abstract The physical abrasion of plastics from simple everyday entered the food chain, with associated risks recently emphasized. Although many studies have reported adverse effects microplastics (MPs) on human, reproductive implications continuous exposure to physically abraded polyethylene terephthalate (PET)‐MPs remain unexplored. Ingestion PET‐MPs (size range: 50–100 µm) in mice 5 34 weeks age at an annual intake relevant dose MPs (5 mg week −1 ) significantly impaired male function....
Purpose The study objective was to investigate the microbial status of coffee, ice and cups used in coffee outlets. This compared food safety practices between franchised single-unit Design/methodology/approach subjects included adopted two different methods: self-answered checklists laboratory tests. We datasets by operation type (franchised vs single-unit). analysed data using independent t -test chi-square Findings Franchised outlets were more likely apply than outlets; however, testing...
Background: Cardiogenic shock (CS) frequently leads to multiorgan failure, often necessitating continuous renal replacement therapy (CRRT) or extracorporeal membrane oxygenation (ECMO). We evaluated the association between CRRT, ECMO, and its prognostic implication in patients with CS. Methods: A total of 1247 CS were enrolled from RESCUE (Retrospective Prospective Observational Study Investigate Clinical Outcomes Efficacy Left Ventricular Assist Device for Korean Patients Shock) registry...
A breath of fresh air: The rate aerial oxidation dihydroethidium and hydrocyanine radical oxidant probes can be selectively reduced by deuteration (see picture). reaction between the deuterated compounds superoxide was a much smaller factor because mechanistic differences two reactions. are more effective than their hydrogen analogues in vitro, cell culture, vivo. Detailed facts importance to specialist readers published as "Supporting Information". Such documents peer-reviewed, but not...
Upon degeneration of photoreceptors in the adult retina, interneurons, including bipolar cells, exhibit a plastic response leading to their aberrant rewiring. Photoreceptor reintroduction has been suggested as potential approach sight restoration, but ability deafferented cells establish functional synapses with is poorly understood. Here we use photocoagulation selectively destroy rabbits while preserving inner retina. We find that rods and cones shift into ablation zone over several weeks,...
Cell necrosis is central to the progression of numerous diseases, and imaging agents that can detect necrotic tissue have great clinical potential. We demonstrate here a small molecule, termed Hoechst-IR, composed DNA binding dye Hoechst near-infrared IR-786, image in vivo via fluorescence imaging. Hoechst-IR detects by extracellular released from cells was able generated myocardial infarction lipopolysaccharide/d-galactosamine (LPS-GalN) induced sepsis.
In this report, we present a new strategy for targeting chemotherapeutics to tumors, based on extracellular DNA. A gemcitabine prodrug was synthesized, termed H-gemcitabine, which is composed of Hoechst conjugated gemcitabine. H-gemcitabine has low toxicity because it membrane-impermeable; however, still high tumor efficacy its ability target E-DNA in tumors. We demonstrate here that wider therapeutic window than free
Freshwater harmful algal blooms (HABs), driven by nutrient inputs from anthropogenic sources, pose unique risks to human and ecological health worldwide. A major contributor is agricultural land use, specifically tile drainage discharge. Small lakes ponds are at elevated risk for HAB appearance, as they uniquely sensitive input. HABs introduce exposure microcystin (MC), hepatotoxic potentially carcinogenic cyanotoxins. To investigate the impact of use on small ponds, 24 sites in central Ohio...
A smoke-derived compound, karrikin (KAR), and an endogenous but as yet unidentified KARRIKIN INSENSITIVE2 (KAI2) ligand (KL) have been identified chemical cues in higher plants that impact on multiple aspects of growth development. Genetic screening light-signaling mutants Arabidopsis thaliana has a mutant designated ply2 (pleiotropic long hypocotyl2) pleiotropic light-response defects. In this study, we used positional cloning to identify the molecular lesion missense mutation...
Fecal microbiota transplantation (FMT) has emerged for the therapeutic treatment of recurrent Clostridioides difficile infection (rCDI) with concurrent inflammatory bowel disease (IBD). As first Iranian population cohort, we examined how gut and their functional profiles change in rCDI patients underlying IBD before after FMT.FMT was performed to eight via colonoscopy. Profiles from donors recipients were investigated using 16S rRNA gene sequence analysis.Patients experienced no flare-ups or...
Floor materials in indoor environments are known to be reservoirs of microbes. We focused on examining bacterial community composition, antibiotic resistance (AR) and microbial source tracking (MST) fecal bacteria the floor surfaces. Swab samples were collected from carpet vinyl floors three different buildings (medical, veterinary, office buildings) high low traffic areas. Bacterial communities determined with 16S rRNA sequencing, AR (tetracycline (tetQ), sulfonamide, carbapenem (KPC)) MST...
Cyanophages are abundant in aquatic environments and play a critical role bloom dynamics, including regulation of cyanobacteria growth photosynthesis. In this study, cyanophages from western Lake Erie water samples were screened for lytic activity against the host cell (Microcystis aeruginosa), which also originated Erie, identified with real-time sequencing (Nanopore sequencing). M. aeruginosa was mixed their dynamic interactions examined over two weeks using atomic force microscopy (AFM)...
Microcystins (MCs) are the most prevalent cyanotoxins reported in freshwater. While numerous studies have examined toxicological impacts of MCs on mammalian systems, very few chronic gut microbiome exposed organisms. Our understanding relationship MCs, especially lysed toxic cyanobacteria, and microbiota is limited. The objective this study was to determine MC-LR Microcystis lysate ingestion a hepatocellular carcinoma mouse model, simulating high-risk population exposure at an...