A5100375921- Listeria monocytogenes in Food Safety
- Epigenetics and DNA Methylation
- Plant Pathogens and Fungal Diseases
- RNA modifications and cancer
- Aquatic Ecosystems and Phytoplankton Dynamics
- Lung Cancer Treatments and Mutations
- Plant-Microbe Interactions and Immunity
Shanghai Institute of Materia Medica
2024
Chinese Academy of Sciences
2024
Guangxi Academy of Agricultural Science
2024
Abstract Third-generation EGFR tyrosine kinase inhibitors (TKIs), exemplified by osimertinib, have demonstrated promising clinical efficacy in the treatment of non-small cell lung cancer (NSCLC). Our previous work has identified ASK120067 as a novel third-generation TKI with remarkable antitumor effects that undergone New Drug Application (NDA) submission China. Despite substantial progress, acquired resistance to EGFR-TKIs remains significant challenge, impeding long-term effectiveness...
This study aimed to provide foundational research for the biological control of postharvest avocado fruits anthracnose and establish a microbial system fruits. The high-throughput sequencing from anthracnose-infected healthy groups was performed using Illumina NovaSeq second-generation technology. results revealed that, except Colletotrichum sp. strain 38#, there were differences in bacterial community structure avocados before after infection, as determined through alpha beta diversity...