A5074257205- Aquaculture disease management and microbiota
- Milk Quality and Mastitis in Dairy Cows
- Microbial infections and disease research
- Vibrio bacteria research studies
- Invertebrate Immune Response Mechanisms
- Aquaculture Nutrition and Growth
- Antimicrobial Peptides and Activities
- Identification and Quantification in Food
- Bacteriophages and microbial interactions
- Infections and bacterial resistance
- Myxozoan Parasites in Aquatic Species
- Animal Disease Management and Epidemiology
- Salmonella and Campylobacter epidemiology
- Peptidase Inhibition and Analysis
- Antibiotic Resistance in Bacteria
- Animal Behavior and Welfare Studies
- Animal Virus Infections Studies
- Leptospirosis research and findings
- Agricultural Systems and Practices
- Insect symbiosis and bacterial influences
- SARS-CoV-2 and COVID-19 Research
- Viral Infectious Diseases and Gene Expression in Insects
- Surgical Sutures and Adhesives
- Vector-Borne Animal Diseases
- Microbial Metabolism and Applications
University of Stirling
2013-2023
National University of Ireland
2002
New South Wales Department of Primary Industries
1977-1983
Veterinary Research Institute
1972-1973
Introduction Aeromonads are ubiquitous in aquatic environments and several species opportunistic pathogens of fish. Disease losses caused by motile Aeromonas species, particularly hydrophila , can be challenging intensive aquaculture, such as at striped catfish ( Pangasianodon hypophthalmus ) farms Vietnam. Outbreaks require antibiotic treatments, but their application is undesirable due to risks posed resistance. Vaccines an attractive prophylactic they must protect against the prevalent...
Rainbow trout fry syndrome (RTFS) is a disease caused by the Gram-negative bacterium Flavobacterium psychrophilum, responsible for significant economic losses in salmonid aquaculture worldwide. The diversity of F. psychrophilum isolates and inherent difficulties vaccinating juvenile fish has hampered development vaccine RTFS. Disease episodes tend to occur between 10–14 °C with necrotic lesions often seen on skin surrounding dorsal fin tail. At present no commercial vaccines are available...
Bacteria from the family Flavobacteriaceae often show low susceptibility to antibiotics. With exception of two Chryseobacterium spp. isolates that were positive for florfenicol resistance gene floR, no clinical genes identified by microarray in 36 salmonid fish could grow ≥ 4 mg/L florfenicol. Whole genome sequence analysis floR revealed presence a region contained antimicrobial tet(X) tetracycline gene, streptothricin and chloramphenicol acetyltransferase gene. In silico 377 published...
Biofloc technology (BFT) is one of the most promising technologies in global aquaculture for purpose improving water quality, waste treatment, and disease prevention intensive systems. However, characterization microbial species antibiotic resistance potentially present biofloc-based environments needed. In this study, we used high-throughput sequencing to comprehensively compare bacterial communities mariculture ponds Penaeus monodon ( P. ), by testing water, biofloc, intestine ....
Abstract Routine application of antimicrobials is the current treatment choice for rainbow trout fry syndrome ( RTFS ) or bacterial coldwater disease BCWD caused by Flavobacterium psychrophilum . In this study, antimicrobial susceptibilities 133 F. isolates, 118 which were from UK , evaluated broth microdilution and disc diffusion methods following VET 04‐A2 03‐A guidelines Clinical Laboratory Standards Institute CLSI ), respectively. Isolates categorized as wild type (fully susceptible, WT...
Recent studies have shown that a key strategy of many pathogens is to use post-translational modification (PTMs) modulate host factors critical for infection. Lysine succinylation (Ksuc) major PTM widespread in prokaryotic and eukaryotic cells, associated with the regulation numerous important cellular processes. Vibrio alginolyticus common pathogen causes serious disease problems aquaculture. Here we used affinity enrichment method LC-MS/MS report first identification 2082 lysine sites on...
Flavobacterium psychrophilum is one of the most important pathogens affecting cultured rainbow trout (Oncorhynchus mykiss). Recent information from UK salmonid farms showed country-wide distribution genetically and serologically divergent clones, which has hampered development a vaccine for fry syndrome. The current study assessed efficacy an injectable polyvalent containing formalin-inactivated F. in trout. was formulated with oil adjuvant (Montanide ISA 760VG) or formalin-killed cells...
Vibrio alginolyticus is a major cause of Vibriosis in farmed marine aquatic animals and has caused large economic losses to the Asian aquaculture industry recent years. Therefore, it necessary control V. effectively. The virulence mechanism alginolyticus, Type III secretion system (T3SS), closely related its pathogenicity. In this study, T3SS gene tyeA was cloned from wild-type strain HY9901 results showed that deduced amino acid sequence shared 75–83% homology with other spp. mutant...
Although Nile tilapia (Oreochromis niloticus) is a well-established aquaculture species globally, there are limited number of commercial vaccines available or used for this species. The majority diseases affecting farmed bacterial, with antibiotics frequently to treat fish. current study was performed optimise the use mucosal by adapting an existing bacterin vaccine against Francisella noatunensis subsp. orientalis (Fno) as proof concept. This has previously provided excellent protection...
Flavobacterium psychrophilum is the causative agent of bacterial cold-water disease (CWBD) and rainbow trout fry syndrome (RTFS), which affect salmonids. To better understand this pathogen its interaction with host during infection, including to support development resistant breeds new vaccines treatments, there a pressing need for reliable reproducible immersion challenge models that more closely mimic natural routes infection. The aim present study was evaluate model developed previously...
Infectious salmon anaemia virus (ISAV) is an orthomyxovirus that has had a significant economic impact on Atlantic farming in Europe, North America and Chile. Monoclonal antibodies (mAbs) were developed against Segment 3 (encoding the viral nucleoprotein, NP) of virus. Six mAbs shown to be specific ISAV recognised all isolates from Scotland, Norway Canada. They reacted with enzyme-linked immunosorbent assay (ELISA), indirect fluorescent antibody technique (IFAT) western blotting. also used...