A5046794253- Aquaculture disease management and microbiota
- Aquaculture Nutrition and Growth
- Animal Genetics and Reproduction
- Physiological and biochemical adaptations
- Reproductive biology and impacts on aquatic species
- CRISPR and Genetic Engineering
- Fish Ecology and Management Studies
- Bone Metabolism and Diseases
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- MicroRNA in disease regulation
- Antioxidant Activity and Oxidative Stress
- Invertebrate Immune Response Mechanisms
- Fish Biology and Ecology Studies
- Metabolomics and Mass Spectrometry Studies
- RNA Interference and Gene Delivery
- Genetic and phenotypic traits in livestock
- Animal Virus Infections Studies
- Cancer, Lipids, and Metabolism
- Bone health and osteoporosis research
- Adipose Tissue and Metabolism
- Microbial infections and disease research
- Immune Response and Inflammation
- RNA Research and Splicing
- interferon and immune responses
- Peroxisome Proliferator-Activated Receptors
Norwegian University of Life Sciences
1999-2024
AquaGen (Norway)
2015-2024
Nofima
2009-2020
Fafo Foundation
2009-2016
Institute of Fisheries and Aquaculture
2012
Norwegian Veterinary Institute
2002
Abstract Infectious pancreatic necrosis virus (IPNV) is the cause of one most prevalent diseases in farmed Atlantic salmon (Salmo salar). A quantitative trait locus (QTL) has been found to be responsible for genetic variation resistance virus. Here we describe how a linkage disequilibrium-based test deducing QTL allele was developed, and it used produce IPN-resistant salmon, leading 75% decrease number IPN outbreaks farming industry. Furthermore, whole-genome sequencing individuals with...
Microalgae, as primary producers of EPA and DHA, are among the most prominent alternative sources to fish oil for n-3 long-chain PUFA in animal human nutrition. The present study aimed assess technical, nutritional health aspects producing n-3-rich Atlantic salmon (Salmo salar) fillets by dietary supplementation increasing levels a DHA-producing Schizochytrium sp. reduced or without use supplemental oil. smolt were fed diets with graded microalgae 12 weeks, during which all showed high feed...
Abstract Background Hyperthermia has been shown in a number of organisms to induce developmental defects as result changes cell proliferation, differentiation and gene expression. In spite this, salmon aquaculture commonly uses high water temperature speed up rate intensive production systems, resulting an increased frequency skeletal deformities. order study the molecular pathology vertebral deformities, Atlantic was subjected hyperthermic conditions from fertilization until after juvenile...
Atlantic salmon migrates from rivers to sea feed, grow and develop gonads before returning spawn in freshwater. The transition marine habitats is associated with dramatic changes the environment, including water salinity, exposure pathogens shift dietary lipid availability. Many physiology metabolism occur across this life-stage transition, but little known about molecular nature of these changes. Here, we use a long-term feeding experiment study transcriptional regulation gut liver both...
DAO Diseases of Aquatic Organisms Contact the journal Facebook Twitter RSS Mailing List Subscribe to our mailing list via Mailchimp HomeLatest VolumeAbout JournalEditorsSpecials 60:11-20 (2004) - doi:10.3354/dao060011 Protection Atlantic salmon Salmo salar against infectious pancreatic necrosis after DNA vaccination Aase B. Mikalsen1, Jacob Torgersen2, Peter Aleström2, Anne-Lill Hellemann3, Erling-Olaf Koppang3, Espen Rimstad1,* 1Department Food Safety and Infection Biology, 2Department...
Abstract Background Spinal disorders are a major cause of disability for humans and an important health problem intensively farmed animals. Experiments have shown that vertebral deformities present complex but comparable etiology across species. However, the underlying molecular mechanisms involved in bone still far from understood. To further explicate involved, we examined fundamental aspects metabolism pathogenesis fusions Atlantic salmon ( Salmo salar ). Results Experimentally, juvenile...
Cardiac muscle is a principal target organ for exercise-induced acclimation mechanisms in fish and mammals, given that sustained aerobic exercise training improves cardiac output. Yet, the molecular underlying such have been scarcely investigated teleosts. Consequently, we studied related to growth, contractility, vascularization, energy metabolism myokine production Atlantic salmon pre-smolts resulting from 10 weeks exercise-training at three different swimming intensities: 0.32 (control),...
Atlantic salmon (Salmo salar L.) with soft fillets are not suited for manufacturing high quality products. Therefore insufficient firmness downgraded, leading to severe economic losses the farming and processing industries. In current study, morphological characteristics of ranging from hard were analysed. Different microscopic techniques applied, including novel methods in this field research: morphometric image analysis, periodic acid Schiff staining, immunofluorescence microscopy,...
The factors of the Sox9-Amh-Cyp19a1 cascade play a crucial role in complex process sex differentiation mammals. involvement Sox9 and Cyp19a1 paralogs single Amh ortholog development gonads brain Atlantic cod was examined by analyzing bimodal sex-dimorphic gene expression patterns, respectively, during early stages maturing males females. Expression sox9a sox9b were initiated at blastulation, both expressed chondrogenic tissue hatched larvae. male-specific adult supports conserved testis...
Abstract Red coloration of muscle tissue (flesh) is a unique trait in several salmonid genera, including Atlantic salmon. The color results from dietary carotenoids deposited the flesh, whereas intensity affected both by diet and genetic components. Herein we report on genome-wide association study (GWAS) to identify variation underlying this trait. Two SNPs ssa26 showed strong associations flesh genes known be involved carotenoid metabolism were located QTL- region: beta-carotene oxygenase...
Abstract Background Atlantic salmon aquaculture operations in the Northern hemisphere experience large seasonal fluctuations seawater temperature. With summer temperatures often peaking around 18-20°C there is growing concern about effects on fish health and performance. Since heart has a major role physiological plasticity acclimation to different thermal conditions fish, we wanted investigate how three eight weeks exposure of adult 19°C, previously shown significantly reduce growth...
Gonadotropin releasing hormone (GnRH) is responsible for stimulation of gonadotropic (GtH) in the hypothalamus-pituitary-gonadal axis (HPG). The regulatory mechanisms brain specificity make promoter attractive silico analysis and reporter gene studies zebrafish (Danio rerio).We have characterized a [Trp7, Leu8] or salmon (s) GnRH variant, gnrh3. includes 1.6 Kb upstream region displays conserved structure 4 exons 3 introns, as seen other species. An defined enhancer at -976 promoter,...
We have examined the nutritional and insulin regulation of mRNA expression transmembrane fatty acid (FA) transporters [FA transport protein-1 (FATP1) CD36] together with lipoprotein lipase (LPL), cytosolic FA carrier binding protein (FABP3), mitochondrial FA-CoA -carnitine palmitoyl transferase carriers (CPT)1 -2 in Atlantic salmon tissues myocyte cell culture. Two weeks fasting diminished FATP1, CD36, LPL adipose tissue, suggesting a reduction uptake, while FABP3 increased liver, probably...