A5049719195- Toxic Organic Pollutants Impact
- Heavy Metal Exposure and Toxicity
- Effects and risks of endocrine disrupting chemicals
- Air Quality and Health Impacts
- Birth, Development, and Health
- Carcinogens and Genotoxicity Assessment
- Breastfeeding Practices and Influences
- Environmental Justice and Health Disparities
- Phytoestrogen effects and research
- Chemical Analysis and Environmental Impact
- Prenatal Substance Exposure Effects
- Infant Nutrition and Health
- Noise Effects and Management
- Trace Elements in Health
- Pesticide Exposure and Toxicity
- Heavy metals in environment
- Per- and polyfluoroalkyl substances research
- Cancer Risks and Factors
- Early Childhood Education and Development
- Occupational and environmental lung diseases
- Gestational Diabetes Research and Management
- Sexual Differentiation and Disorders
- Mercury impact and mitigation studies
- Climate Change and Health Impacts
- Neonatal Respiratory Health Research
National Institute of Environmental Health Sciences
2014-2024
National Institutes of Health
2009-2024
Triangle
1979-2017
Quest Diagnostics (United States)
2012
Research Triangle Park Foundation
1987-2009
CDC Foundation
2009
Children's Hospital of Philadelphia
1993-2009
National Institute of Biomedical Imaging and Bioengineering
2009
University of Cincinnati
2003
Harvard University
2003
This paper deals with some basis properties of screening tests. Such tests purport to separate people disease from without. Minimal criteria for such a process be test are discussed. Various ways judging the goodness examined. A common use is estimate prevalence disease; frequency positive shown bad estimate, and necessary adjustmants given.
In 1979, a mass poisoning occurred in Taiwan from cooking oil contaminated by thermally degraded polychlorinated biphenyls. Because these chemicals persist human tissue, children born to female patients after the outbreak were exposed utero. 1985, 117 affected women and 108 unexposed controls examined evaluated. The shorter lighter than controls; they had abnormalities of gingiva, skin, nails, teeth, lungs more frequently did controls. showed delay developmental milestones, deficits on...
Breastfed infants in the United States have lower rates of morbidity, especially from infectious disease, but there are few contemporary studies developed world effect breastfeeding on postneonatal mortality. We evaluated mortality using 1988 National Maternal and Infant Health Survey (NMIHS) data.Nationally representative samples 1204 who died between 28 days 1 year causes other than congenital anomaly or malignant tumor (cases death) 7740 children were still alive at (controls) included....
The authors measured polychlorinated biphenyls (PCBs) and dichlorodiphenyl dichloroethene (DDE) in maternal serum, cord blood, placenta, serial samples of breast milk from 868 women. Almost all showed detectable levels both chemicals. Overall, values for DDE this study are within the range those found previously, whereas PCBs somewhat higher. Possible causes variation were investigated. For DDE, older women, Black cigarette smokers, women who consumed sport fish during pregnancy had higher...
Thousands of children, especially poor children living in deteriorated urban housing, are exposed to enough lead produce cognitive impairment. It is not known whether treatment reduce blood levels prevents or reduces such
Polychlorinated biphenyls (PCBs) are persistent pollutants that ubiquitous in the food chain, and detectable amounts blood of almost every person most populations have been examined. Extensive evidence from animal studies shows PCBs neurotoxins, even at low doses. Interpretation human data regarding low-level, early-life PCB exposure subsequent neurodevelopment is problematic because levels were not similarly quantified across studies. We expressed 10 a uniform manner using combination...
We followed 858 children from birth to one year of age determine whether the presence polychlorinated biphenyls (PCBs) and dichlorodiphenyl dichloroethene (DDE) in breast milk affected their growth or health. Neither chemical showed an adverse effect on weight frequency physician visits for various illnesses, although differences were seen between breast-fed bottle-fed children, with being heavier having more frequent gastroenteritis otitis media. Children mothers higher levels DDE markedly...
Objective. Some children in the United States continue to be exposed levels of lead that increase their risk for lowered intellectual functioning and behavior problems. It is unclear whether chelation therapy can prevent or reverse neurodevelopmental sequelae toxicity. The objective this study was determine with succimer (dimercaptosuccinic acid) referral blood between 20 44 μg/dL (0.96-2.12 μmol/L) at 12 33 months age has benefits 7 years. Methods. Treatment Lead-Exposed Children (TLC) a...
Maternal obesity (defined as prepregnancy body mass index [BMI] >or=30 kg/m) is associated with increased risk of neonatal death. Its association infant death, postneonatal and cause-specific death less well-characterized.We studied the between maternal by using 1988 US National Infant Health Survey data. A case-control analysis 4265 deaths 7293 controls was conducted SUDAAN software. Self-reported BMI weight gain were used in primary analysis, whereas variables medical records a subset 4308...
Perfluoroalkyl substances (PFASs) are synthetic compounds that widely used in industry and often detectable humans. In pregnant rats their pups, PFASs can interfere with thyroid hormone homeostasis. humans, maternal hormones supply the fetus throughout pregnancy, play a critical role fetal growth neurodevelopment.We investigated association between PFAS exposure status women neonates.In study of environmental health Taiwan, we measured serum concentrations nine four for 285 third trimester,...
The association between lead exposure and children's IQ has been well studied, but few studies have examined the effects of blood concentrations on behavior.To evaluate behavioral problems in a community sample Chinese preschool children with mean concentration less than 10 µg/dL.A prospective cohort study was conducted at 4 preschools Jintan, Jiangsu province China. Participants included 1341 aged 3 to 5 years.Lead.Blood were measured years. Behavioral assessed using versions Child Behavior...
Increases in peak blood lead concentrations, which occur at 18-30 months of age the United States, are thought to result lower IQ scores 4-6 years age, when becomes stable and measurable. Data from a prospective study conducted Boston suggested that concentrations 2 were more predictive cognitive deficits older children than later or measured concurrently with IQ. Therefore, cross-sectional associations between school-age have been widely interpreted as residual effects higher an earlier...
Worldwide declines in the duration of lactation are cause for public health concern. Higher levels dichlorodiphenyl dichloroethene (DDE) have been associated with shorter durations United States. This study examined whether this relationship would hold an agricultural town northern Mexico.Two hundred twenty-nine women were followed every 2 months from childbirth until weaning or child reached 18 age. DDE was measured breast milk samples taken at birth, and to see how long they...
Data from several studies indicate that children of mothers who smoked during pregnancy may be at a risk overweight compared with non-smoking mothers. The size this relation, however, is unclear, as the age which it becomes detectable.Prospective data for 34 866 enrolled in US Collaborative Perinatal Project were analysed to examine maternal smoking relation weight, height, and body mass index (BMI) offspring ages 1, 3, 4, 7, 8 years.Compared non-smokers, smokers had (i) weight was lower...
BACKGROUND. Lead exposure in childhood lowers IQ scores, but its effect on children's behavior is less clear. Because IQ, per se, affects behavior, measuring the direct of lead requires and then adjusting for IQ. In addition, either peak blood concentration, usually at 2 years old, or lower level measured school age may be most relevant. Few studies have all this information. OBJECTIVES. The purpose work was to differentiate indirect through examine strength association concurrent...