A5031871323- Liver Disease Diagnosis and Treatment
- Liver Disease and Transplantation
- Hepatitis C virus research
- Gastroesophageal reflux and treatments
- Esophageal and GI Pathology
- Hepatitis B Virus Studies
- Helicobacter pylori-related gastroenterology studies
- Hepatitis Viruses Studies and Epidemiology
- Eosinophilic Esophagitis
- Potassium and Related Disorders
- Gastrointestinal Bleeding Diagnosis and Treatment
- Organ Transplantation Techniques and Outcomes
- Gallbladder and Bile Duct Disorders
- Gastrointestinal disorders and treatments
- Microscopic Colitis
- Diagnosis and treatment of tuberculosis
- Drug-Induced Hepatotoxicity and Protection
- Gastrointestinal motility and disorders
- Biliary and Gastrointestinal Fistulas
- Inflammatory Bowel Disease
- Intestinal and Peritoneal Adhesions
- Gastric Cancer Management and Outcomes
- Appendicitis Diagnosis and Management
- Pancreatitis Pathology and Treatment
- Pancreatic and Hepatic Oncology Research
Nova Southeastern University
2024
Aga Khan University
2001-2023
Aga Khan University Hospital
2006-2023
Ayub Medical College
2023
Abbott (Germany)
2023
Pakistan Institute of Medical Sciences
2023
Abbott (Sweden)
2023
Khyber Medical College
2020-2023
Khyber Teaching Hospital
2023
Russells Hall Hospital
2023
Insulin is secreted in a high frequency pulsatile manner. These pulses are delivered directly into the portal vein and then undergo extraction dilution before delivery systemic circulation. The reported of these insulin estimated peripheral blood varies from an interpulse interval 4–20 min. We postulated that this discrepancy due to attenuation pulse signal circulation vs. In present study we measured release human subjects who had indwelling transjugular intrahepatic portasystemic stent...
Infections with hepatitis B virus (HBV) and C (HCV) can lead to chronic liver disease hepato-cellular carcinoma (HCC). This cross-sectional study estimated the prevalence identified risk factors associated Hepatitis surface antigen (HBsAg) HCV antibody (anti-HCV) sero-positivity among children 1 15 years of age. The targeted low middle socioeconomic population that comprises 80% 85% population. Consent was obtained from parents eligible before administering questionnaire collected a blood...
OBJECTIVES: Data are scarce on the head-to-head efficacy of terlipressin and octreotide as an adjuvant therapy to endoscopic management variceal bleed. The aim this study was compare safety with band ligation in patients esophageal bleeding. METHODS: Cirrhotic bleed were randomized admission receive (group A) or B) along placebo other arm a doubleblind fashion. two groups compared for efficacy, safety, overall survival, length hospital stay. "Control bleed" measure octreotide. Factors...
Background: Cytochrome P450 plays a pivotal role in metabolizing drugs, hormones, and vitamins with genetic variability influencing enzymatic activity. Genetic consortiums categorize variables such as CYP3A4-rs2242480 rs2740574 third-level evidence, indicating the need for further research into their health implications pharmacogenetic relevance carbamazepine metabolism. This study explores distribution patterns of selected genes correlation gender our population, aiming to advance...
Background: Breast cancer is a significant cause of female morbidity and mortality in Indian women. The incidence breast rising India (22.9%) it now the second most commonly diagnosed women here. Aim: To evaluate difference between pre- post-menopausal regarding risk factor, nature disease presentation, tumor characteristic, management. determine compare premenopausal postmenopausal prevalent high-risk group for carcinoma breast. clinical common type pathological type, management Methods:...
Abstract Background and Aims: The global epidemiology of hepatitis delta virus (HDV) infection is changing. This study was performed to determine the clinical impact in Pakistan. Methods: Countrywide data collected from 1994 2001. A total 8721 patients were tested for antibody. subset 97 antibody reactive inpatients with chronic liver disease compared admitted due B alone. Results: Of tested, 1444 (16.6%) Most males (87.4%, P < 0.001) younger (mean age 31 years, HDV non‐reactive patients....
Hepatitis C virus (HCV) is classified into different types depending on nucleotide sequence variability. Detailed information the distribution of various HCV genotypes in some geographical areas available but little known about Pakistan. In this study, a 5' non-coding region (NCR)-based restriction fragment length polymorphism (RFLP) genotyping assay was used to investigate genotype large series HCV-infected patients Karachi, Serum samples from 74 hepatitis B surface antigen (HBsAg)-negative...
To determine the predictive factors for early aspiration in liver abscess.A retrospective analysis of all patients with abscess from 1995 to 2004 was performed. Abscess diagnosed as amebic 661 (68%) patients, pyogenic 200 (21%), indeterminate 73 (8%) and mixed 32 (3%). Multiple logistic regression performed total 966 738 (76%) male, mean age 43 +/- 17 years, were evaluated: 540 responded medical therapy while adjunctive percutaneous 426 patients. Predictive were: > or = 55 size 5 cm,...
Abstract Background The aim of this study was to determine the effect commonly self-prescribed proton pump inhibitors (PPI) on results rapid urease test and histology for diagnosis H. pylori infection. Methods One hundred-nine consecutive patients with dyspeptic symptoms attending endoscopy suite were enrolled in study. Antrum biopsy specimens collected at (Pronto Dry, Medical Instrument Corp, France) histopathology. Sensitivity, specificity, positive predictive value (PPV), negative (NPV)...
The aim of the study was to assess knowledge and practices primary care physicians in diagnosis management Helicobacter pylori (H. pylori) infection developing country. This convenient sample based, cross sectional conducted Karachi, Pakistan from March 2008 August through a pretested self-designed questionnaire, which contained 11 items pertaining H. route transmission, diagnosis, indication for testing, treatment options, follow up source information. Out 509 physicians, 451 consented...
ABSTRACT Background & Aims Non‐selective β‐blockers (NSBBs) and endoscopic variceal‐ligation (EVL) have similar efficacy preventing first variceal bleeding. Compensated decompensated cirrhosis are markedly different stages, which may impact treatment outcomes. We aimed to assess the of NSBBs vs EVL on survival in patients with high‐risk varices without previous bleeding, stratifying risk according compensated/decompensated stage cirrhosis. Methods By systematic review, we identified RCTs...
Percutaneous endoscopic gastrostomy tube has now become a preferred option for the long-term nutritional support device patients with dysphagia. There is considerable debate about health issues related to quality of life these patients. Our aim study was assess outcome and perspectives patients/care givers, acceptability percutaneous placement.This descriptive analytic conducted in patients, who have undergone placement during January 1998 till December 2004. Medical records were evaluated...
To study the safety and utility of performing an oesophago-gastro-duodenoscopy (EGD) in setting acute myocardial infarction (AMI).Case records all patients who underwent EGD for various indications within 4 weeks AMI between January 2001 April 2006 were analyzed. Demographic data, endoscopy, outcomes complications noted. Main outcome measures included endoscopy AMI.A total 87 EGDs performed on 85 with AMI. Seventy (83%) had a non-ST elevation MI, whereas 15 (17%) ST MI. Mean time was 6+/-1.8...