A5003162358- Plant and Fungal Interactions Research
- Plant Virus Research Studies
- Insect symbiosis and bacterial influences
- Gut microbiota and health
- Cancer Research and Treatments
- Vaccine Coverage and Hesitancy
- Insect and Pesticide Research
- Ethics in Clinical Research
- Insect Utilization and Effects
- Viral Infectious Diseases and Gene Expression in Insects
- Endoplasmic Reticulum Stress and Disease
- Healthcare Systems and Challenges
- Adrenal Hormones and Disorders
- Virus-based gene therapy research
- CRISPR and Genetic Engineering
- Plant-Microbe Interactions and Immunity
- Hormonal Regulation and Hypertension
- Bacteriophages and microbial interactions
- Plant Pathogens and Fungal Diseases
- Plant Disease Management Techniques
- Plant Disease Resistance and Genetics
- Viral Infections and Outbreaks Research
- Autophagy in Disease and Therapy
- Mitochondrial Function and Pathology
- Cancer Cells and Metastasis
European University Cyprus
2023-2025
University of Hertfordshire
2018-2025
Western Sydney University
2025
Imperial College London
2018-2021
Polymycoviridae is a growing family of mycoviruses whose members typically have non-conventional capsids and multi-segmented, double-stranded (ds) RNA genomes. Beauveria bassiana polymycovirus (BbPmV) 1 known to enhance the growth virulence its fungal host, entomopathogenic ascomycete popular biological control agent B. . Here we report complete sequence BbPmV-3, which has six genomic dsRNA segments. Phylogenetic analysis RNA-dependent polymerase (RdRp) protein sequences revealed that...
Mycoviral infection can either be asymptomatic or have marked effects on fungal hosts, influencing them positively negatively. To fully understand the of mycovirus host, transcriptomic profiling four Beauveria bassiana isolates, including EABb 92/11-Dm that harbors mycoviruses, was performed 48 h following Tenebrio molitor via topical application injection. Genes participate in carbohydrate assimilation and transportation, those essential for survival oxidative stress tolerance, calcium...
Background: Current evidence suggests that more than half of all antimicrobials are used in the sector food-producing animals, thus constituting a major risk factor for development and spread antimicrobial resistance (AMR). Methods: This cross-sectional study assessed knowledge, attitudes, practices regarding (AMR) use (AMU) among veterinarians (n = 26) working with animals operators 165) establishments keep across districts Cyprus between October December 2024. Results: Most demonstrated...
Antimicrobial resistance (AMR) constitutes a pressing and intensifying global health crisis, significantly exacerbated by the inappropriate utilization excessive application of antibiotics in livestock agriculture. The use antibiotics, including prophylactic metaphylactic administration as well growth-promotion applications, exacerbates selective pressures, fostering proliferation multidrug-resistant (MDR) bacterial strains. Pathogens such Escherichia coli, Salmonella spp., Staphylococcus...
The use of mycoviruses to manipulate the virulence entomopathogenic fungi employed as biocontrol agents may lead development novel methods control attacks by insect pests. Such approaches are urgently required, existing agrochemicals being withdrawn from market due environmental and health concerns. aim this work is investigate presence diversity in large panels fungi, mostly Spain Denmark. In total, 151 isolates belonging genera Beauveria, Metarhizium, Lecanicillium, Purpureocillium,...
A new double-stranded (ds) RNA mycovirus has been identified in isolate Ds752-1 of the phytopathogenic fungus Dothistroma septosporum, causal agent needle blight, also known as red band blight or pine blight. septosporum chrysovirus 1 (DsCV-1) is a member genus Alphachrysovirus family Chrysoviridae. The DsCV-1 genome comprises four dsRNA elements designated 1, 2, 3, and 4 from largest to smallest. dsRNA1 encodes an RNA-dependent polymerase (RdRP) that most similar RdRP Erysiphe necator...
Background The VACCELERATE Pan-European Scientific network aims to strengthen the foundation of vaccine trial research across Europe by following principles equity, inclusion, and diversity. Volunteer Registry provides access sites European region supports a sustainable volunteer platform for identifying potential participants forthcoming clinical research. Objective aim this study was approach members patient advocacy groups (PAGs) assess their willingness register perspectives related...
A Portuguese isolate of Aspergillus fumigatus was found to contain three double-stranded (ds) RNA elements ranging in size from 1.1 1.8 kbp and comprising the genome a strain partitivirus 1 (AfuPV-1) previously thought only two largest dsRNA elements. The sequence smallest element is described here, completing AfuPV-1 genome. Sequence analysis revealed an open reading frame encoding protein unknown function similar distantly related identified other members family Partitiviridae.
This comprehensive review elucidates the profound relationship between human microbiome and breast cancer managrement. Recent findings highlight significance of microbial alterations in tissues, such as gut breast, their role influencing risk, development, progression, treatment outcomes. We delve into how can modulate systemic inflammatory responses estrogen levels, thereby impacting initiation therapeutic drug efficacy. Furthermore, we explore unique diversity within tissue, indicating...
The cosmopolitan insect-pathogenic fungus and popular biocontrol agent Beauveria bassiana can be used to control Anopheles mosquito populations restrict the spread of malaria, deadliest vector-borne infectious disease in world caused by protozoan parasite Plasmodium. Here, we establish that infection with a double-stranded (ds)RNA mycovirus, polymycovirus (BbPmV)-1, significantly reduces B. virulence against A. coluzzii, main vector malaria. BbPmV-1-mediated hypovirulence at least partially...
<sec> <title>BACKGROUND</title> The VACCELERATE Pan-European Scientific network aims to strengthen the foundation of vaccine trial research across Europe by following principles equity, inclusion, and diversity. Volunteer Registry provides access sites European region supports a sustainable volunteer platform for identifying potential participants forthcoming clinical research. </sec> <title>OBJECTIVE</title> aim this study was approach members patient advocacy groups (PAGs) assess their...