- Epilepsy research and treatment
- Glioma Diagnosis and Treatment
- Pharmacological Effects and Toxicity Studies
- Radiomics and Machine Learning in Medical Imaging
- Neonatal and fetal brain pathology
- Artificial Intelligence in Healthcare and Education
- Anesthesia and Sedative Agents
- Brain Metastases and Treatment
- Cerebrospinal fluid and hydrocephalus
- Genetics and Neurodevelopmental Disorders
- Neuroblastoma Research and Treatments
- Machine Learning in Healthcare
- Hepatocellular Carcinoma Treatment and Prognosis
- Tracheal and airway disorders
- Pediatric Hepatobiliary Diseases and Treatments
- Drug Transport and Resistance Mechanisms
- Vascular Anomalies and Treatments
- Neuroendocrine Tumor Research Advances
- Genomics and Rare Diseases
- Family and Disability Support Research
- Liver Disease Diagnosis and Treatment
- Chromatin Remodeling and Cancer
- Ocular Oncology and Treatments
- Vascular Malformations Diagnosis and Treatment
- Traumatic Brain Injury Research
Key Laboratory of Guangdong Province
2025
Chongqing Medical University
2022-2024
Children's Hospital of Chongqing Medical University
2022-2024
University of California, Los Angeles
2024
The First Affiliated Hospital, Sun Yat-sen University
2024
Sun Yat-sen University
2023-2024
China International Science and Technology Cooperation
2023
National Clinical Research
2022
Fujian Medical University
2022
Union Hospital
2022
Background The COVID-19 pandemic, caused by the SARS-CoV-2 virus, has necessitated reliable and authoritative information for public guidance. World Health Organization (WHO) been a primary source of such information, disseminating it through question answer format on its official website. Concurrently, ChatGPT 3.5 4.0, deep learning-based natural language generation system, shown potential in generating diverse text types based user input. Objective This study evaluates accuracy generated...
Lobular capillary hemangioma (LCH), previously known as pyogenic granuloma, is a benign vascular lesion commonly found within the oral and nasal cavities. However, it rarely encountered trachea, especially in pediatric patients, where manifests hemoptysis, cough, wheeze, frequently misdiagnosed bronchitis or asthma. There limited literature on presentation, behavior, management of tracheal LCH. Herein, we describe rare case LCH an 11-year-old boy with history which was successfully managed...
Neonatal posthemorrhagic hydrocephalus remains a common complication in preterm infants, with high rates of mortality and morbidity, placing parents at risk anxiety depression. We sought to investigate the neurodevelopmental outcomes infants who underwent surgery psychological effect on their parents.We retrospectively analysed all born between 2014 2020 Children's Hospital Chongqing Medical University, China. The 28 patients were evaluated by Pediatric Stroke Outcome Measure score, states...
Objective The study aimed to explore the association between site of interictal epileptic discharges (IEDs) on postoperative electroencephalogram (EEG) and seizure recurrence after antiepileptic drug (AED) withdrawal. hypothesizes that concordance IED sites with surgical indicates incomplete resection focus, while non-concordance changes or cortical stimulation. former has a higher risk recurrence. Methods We retrospectively analyzed EEG pattern 182 consecutive children who underwent...
Molecular subgroups influence the vascular architecture within medulloblastomas, particularly wingless (WNT) subgroup, which contributes to its propensity for primary tumor hemorrhage. Whether this mechanism affects intraoperative blood loss remains unknown. This study aimed assess association between WNT medulloblastoma and predisposition loss.
With the evolution of data algorithms and personalized push systems in mobile applications, patients who have searched for disease-related information may repeatedly receive similar content on app homepages or through notifications. This study aims to assess influence health-related delivered applications anxiety depression levels caregivers pediatric oncology patients.
Non-hypervascular hypointense nodules (NHHNs) can transform into hypervascular hepatocellular carcinoma (HCC) during the long-term follow-up. However, risk factors for NHHN transformation in chronic hepatitis B virus (HBV)-infected populations are unknown. This study assessed predictive value of gadoxetic acid-enhanced magnetic resonance imaging (MRI) HCC development patients with HBV infection. A total 86 infection who underwent MRI at First Affiliated Hospital Sun Yat-sen University...
Objective Epilepsy dramatically affects the quality of life (QoL) children, and resection surgery can improve their QoL by reducing seizures or completely controlling them. Children who have postoperative tend to show a poorer QoL. The aim present study was investigate children with after its influencing factors. Methods In study, we retrospectively reviewed 151 consecutive underwent surgery. We then divided them into two groups, seizure seizure-free according outcomes 1 year Variables were...
Background and Objectives: After failed epilepsy surgery, patients often revert to an antiseizure medication (ASM) ASM regimen, which can be adjusted or optimized in three ways: increasing the dose, alternative therapy, combination therapy. It is unclear type of adjustment method improve outcomes. Materials Methods: Children who underwent epileptic resection surgery at Department Neurosurgery, Children's Hospital Chongqing Medical University between January 2015 December 2021 were included...
<sec> <title>BACKGROUND</title> The COVID-19 pandemic, caused by the SARS-CoV-2 virus, has necessitated reliable and authoritative information for public guidance. World Health Organization (WHO) been a primary source of such information, disseminating it through question answer format on its official website. Concurrently, ChatGPT 3.5 4.0, deep learning-based natural language generation system, shown potential in generating diverse text types based user input. </sec>...
Background: Focal cortical dysplasia (FCD) is the most frequent histopathology type in children with refractory epilepsy undergoing surgery. Nearly 40% of FCD patients still suffer from seizures after surgery, but currently there are no effective tools to predict postoperative outcomes children. Methods: We retrospectively reviewed clinical data 97 secondary focal who had undergone resection surgery Children's Hospital Chongqing Medical University June 2013 September 2019. Univariate and...
To construct a prediction nomogram model for the postoperative seizure outcomes in children with focal cortical dysplasia (FCD).We retrospectively reviewed clinical data of 97 epilepsy secondary to FCD who had undergone resection surgery at Children's Hospital Chongqing Medical University from June 2013 September 2019. Univariate and multivariate Cox proportional hazards regression were used explore predictors persistent seizure, outcome was developed. The C-index chosen evaluate...
Abstract Purpose Targeted mutational analysis has been widely used to predict medulloblastoma molecular subgroups. We aimed identify a gene mutation pattern for individual recurrent risk assessment patients with medulloblastoma. Methods In this monocenter cohort analysis, who experienced recurrence were analyzed clinical outcomes, including anatomic and temporal patterns of relapse post-recurrence survival. Differentially genes examined using panel 39 build classifier an elastic net...