Zhihua Ouyang

ORCID: 0000-0002-9355-7718
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About
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Research Areas
  • Spine and Intervertebral Disc Pathology
  • Rock Mechanics and Modeling
  • Geomechanics and Mining Engineering
  • Spinal Fractures and Fixation Techniques
  • Musculoskeletal pain and rehabilitation
  • Anesthesia and Pain Management
  • Geoscience and Mining Technology
  • Geotechnical and Geomechanical Engineering
  • Medical Imaging and Analysis
  • Pelvic and Acetabular Injuries
  • Bioactive Natural Diterpenoids Research
  • Groundwater flow and contamination studies
  • Hydraulic Fracturing and Reservoir Analysis
  • Osteoarthritis Treatment and Mechanisms
  • Geophysical Methods and Applications
  • Drilling and Well Engineering
  • Computational Drug Discovery Methods
  • Spinal Cord Injury Research
  • Geotechnical Engineering and Analysis
  • Dam Engineering and Safety
  • Tribology and Lubrication Engineering
  • Scoliosis diagnosis and treatment
  • Plant Toxicity and Pharmacological Properties
  • Seismic Waves and Analysis
  • Tailings Management and Properties

Jiangxi University of Traditional Chinese Medicine
2025

Nanchang University
2024

University of South China
2016-2022

First Affiliated Hospital of University of South China
2013-2021

Wuhan University of Science and Technology
2005-2021

University of Pittsburgh
2021

Central South University
2017

Xiangya Hospital Central South University
2017

China Coal Research Institute (China)
2016

Wuhan University of Technology
2012

Thyroid cancer (TC) is the most common endocrine malignancy, with a rapidly increasing global incidence. Scutellariae Barbatae Herba (SBH) exhibits significant antitumor activity; however, its mechanism against TC remains unclear. This study aims to explore immunotherapeutic of SBH in treating through network pharmacology, bioinformatics analysis, and experimental validation. In TCMSP database, active components potential targets were screened construct drug-component-target-disease network....

10.1038/s41598-025-86733-1 article EN cc-by-nc-nd Scientific Reports 2025-01-20

10.1016/0148-9062(93)90701-e article EN International Journal of Rock Mechanics and Mining Sciences & Geomechanics Abstracts 1993-04-01

Abstract Background Recently, a percutaneous spinal endoscopy unilateral posterior interlaminar approach to perform bilateral decompression has been proposed for use in treatment of lumbar stenosis, As development and supplement traditional surgery, its advantages regarding therapeutic effects prognosis, such as minor soft tissue damage, little intraoperative blood loss, quick return daily life. However, there are few analyses this surgery with follow-up more than 1 year,we conducted study...

10.1186/s12891-021-04100-3 article EN cc-by BMC Musculoskeletal Disorders 2021-03-01

With the application of large amount pulverised coal injection into blast furnace, hydrogen content in gas will increase, which accelerates reduction iron ore lump zone furnace as well carbon-deposition reaction. This study has investigated effect addition on reaction during pellets through thermodynamic calculation and experiment. The results show that H2 can promote reaction, while increase temperature CO2 significantly inhibit it. preference region for C formation is about 600°C....

10.1080/03019233.2016.1263782 article EN Ironmaking & Steelmaking Processes Products and Applications 2016-12-20

10.1007/bf01042858 article EN Rock Mechanics and Rock Engineering 1991-01-01

This prospective observational study included 22 patients who were diagnosed with symptomatic degenerative disc disease treated via artificial replacement (ADR) a laparoscopic technique.The current aimed to assess the safety and efficacy of ADR using technique for lumbar herniation.Symptomatic is major cause low back pain segmental instability. has increased in popularity as an alternative treatment herniation. However, traditional approach spinal surgery carries risk catastrophic bleeding...

10.1097/brs.0000000000001820 article EN Spine 2016-09-20

Multilevel cervical reconstruction and fusion after tuberculosis has always been a challenge. The current implantation materials for fusion, including titanium mesh, cage, plate are limited by its inferior biological mechanical characteristics the properties of metallic material. This led to increased risk recurrent infection surgery. In addition, unique nature results in low rate high recurrence. case report presents 1 patient who suffered from long segmental had surgery using vascularized...

10.1097/md.0000000000009382 article EN cc-by-nc Medicine 2018-01-01

Early-onset scoliosis (EOS) remains a challenging condition for which current nonfusion surgeries require iterative lengthening surgeries. A growing rod with sliding pedicle screw system (GRSPSS) was developed to treat spinal deformities without repeated operative lengthening. This study performed evaluate whether GRSPSS had similar stability as conventional maintain deformity correction. serial-linkage robotic manipulator six-axis load cell positioned on the end-effector utilized mechanical...

10.1155/2019/9535070 article EN cc-by Journal of Healthcare Engineering 2019-06-12

Study Design Retrospective study. Objective To analyze the causes of and factors influencing early recurrence after TELD performed in treatment lumbar disc herniation. Methods We included 285 patients with single-segment herniation treated using transforaminal endoscopy discectomy from January 2017 to December 2019 at First Affiliated Hospital University South China. Patients were classified into non-early groups based on clinical symptoms MRI reexamination. Imaging data (eg, height index...

10.1177/21925682221096061 article EN cc-by-nc-nd Global Spine Journal 2022-05-17

Abstract Purpose Inflammatory and oxidative stress upregulates matrix metalloproteinase (MMP) activity, leading to intervertebral disc degeneration (IDD). Gene therapy using human tissue inhibitor of 1 (hTIMP1) has effectively treated IDD in animal models. However, persistent unregulated transgene expression may have negative side effects. We developed a recombinant adeno-associated viral (AAV) gene vector, AAV-NFκB-hTIMP1, that only expresses the hTIMP1 under conditions stress. Methods...

10.1007/s00586-021-06728-0 article EN cc-by European Spine Journal 2021-02-01

Abstract Developing a method for the tandem hydrogenative hydrogenolysis of bio‐based furfuryl aldehydes to methylfurans is crucial synthesizing sustainable biofuels and chemicals; however, it poses challenge due easy hydrogenation C=C bond difficult cleavage C−O bond. Herein, palladium (Pd) single‐atom‐supported covalent organic framework was fabricated showed unique 2,5‐dimethylfuran yield up 98.2 % when reacted with 5‐methyl aldehyde in an unprecedented water solvent at 30 °C....

10.1002/ange.202418790 article EN Angewandte Chemie 2024-11-06

Underground mining activities make the fractures in natural rock mass develop randomly. The elastic modulus of fractured Em is changed with redistribution and development fractures. An equivalent model structured to represent hydraulic conductivity strain because continuum theory. Dimensional analysis very useful build relationship parameters complex physical phenomena. Based on engineering phenomenon groundwater flowing into goaf along fracture mass, a fuzzy expression among such as...

10.1155/2021/2803837 article EN Mathematical Problems in Engineering 2021-02-12

In engineering, the method of charts can provide a convenient query for specific engineering problems. To basis potential hazard evaluation and rational governance goaf, it is necessary to study quantitative range goaf roof caving. Undoubtedly, used visually caving simplify workload evaluation. Therefore, methods dimensional analysis, numerical simulation, linear interpolation are introduced dimensionless predicting range. The analysis establish fuzzy function relationship among influence...

10.1155/2021/7382550 article EN Mathematical Problems in Engineering 2021-07-31

10.1016/0307-904x(89)90161-3 article EN Applied Mathematical Modelling 1989-12-01
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