A5017819504- Diphtheria, Corynebacterium, and Tetanus
- Intramuscular injections and effects
- Cardiac, Anesthesia and Surgical Outcomes
- Historical Medical Research and Treatments
- Immune Response and Inflammation
- Adrenal Hormones and Disorders
- Intestinal and Peritoneal Adhesions
- Muscle and Compartmental Disorders
- Respiratory viral infections research
- Frailty in Older Adults
- Immunodeficiency and Autoimmune Disorders
- Electrolyte and hormonal disorders
- Anesthesia and Sedative Agents
- Airway Management and Intubation Techniques
- Hip and Femur Fractures
Karlstad Central Hospital
2015-2021
Institut Pierre Louis d‘Épidémiologie et de Santé Publique
2021
Assistance Publique – Hôpitaux de Paris
2021
Inserm
2021
Sorbonne Université
2021
Autosomal inborn errors of type I IFN immunity and autoantibodies against these cytokines underlie at least 10% critical COVID-19 pneumonia cases. We report very rare, biochemically deleterious X-linked TLR7 variants in 16 unrelated male individuals aged 7 to 71 years (mean: 36.7 years) from a cohort 1,202 patients 0.5 99 52.9 with unexplained pneumonia. None the 331 asymptomatically or mildly infected 1.3 102 38.7 tested carry such (p = 3.5 × 10-5). The phenotypes five hemizygous relatives...