- Transplantation: Methods and Outcomes
- Mechanical Circulatory Support Devices
- Renal Transplantation Outcomes and Treatments
- Organ Transplantation Techniques and Outcomes
- Cardiac Structural Anomalies and Repair
- COVID-19 and healthcare impacts
- Head and Neck Cancer Studies
- Congenital Heart Disease Studies
- Organ and Tissue Transplantation Research
- Hepatitis C virus research
- Cardiac Valve Diseases and Treatments
- Cardiac pacing and defibrillation studies
- Cardiac Arrhythmias and Treatments
- Migration, Health and Trauma
- Meta-analysis and systematic reviews
- Cardiac and Coronary Surgery Techniques
- Cardiomyopathy and Myosin Studies
- Racial and Ethnic Identity Research
- Cardiovascular Health and Risk Factors
- Cardiac, Anesthesia and Surgical Outcomes
- Organ Donation and Transplantation
- Tracheal and airway disorders
- Heart Failure Treatment and Management
- Cardiovascular Issues in Pregnancy
- Fuel Cells and Related Materials
Medical University of South Carolina
2022-2024
Washington University in St. Louis
2024
University Hospitals of Cleveland
2019-2023
Damascus University
2012
Limited donor availability and evolution in procurement techniques have renewed interest heart transplantation (HT) with donation after circulatory death (DCD). The aim of this study is to evaluate outcomes HT using DCD the United States.The Network for Organ Sharing registry was used identify adult recipients from 2019 2021. Recipients were stratified between brain death. Propensity-score matching performed. Cox proportional hazards independent predictors 1-year mortality. Kaplan-Meier...
Objectives: The aim of this study was to summarize waitlist and transplant outcomes in kidney, liver, lung, heart transplantation using organ donation after circulatory death (DCD). Summary Background: DCD has expanded the donor pool for solid transplantation, most recently transplantation. Methods: United Network Organ Sharing registry used identify adult candidates recipients recent allocation policy eras transplant. Transplant were grouped by acceptance criteria versus brain-dead donors...
Background: No reliable serum diagnostic test currently exists for peripheral arterial disease (PAD). We previously observed that circulating Fatty Acid Synthase (cFAS) is elevated in individuals with chronic limb threatening ischemia (CLTI). Objectives: hypothesized cFAS can be an independent biomarker PAD and CLTI. Methods: Patients with/without CLTI were retrospectively reviewed. Total content was evaluated using ELISA normalized to total protein. Patient demographics incidence collected...
Background Impella devices are increasingly utilized as a bridge to heart transplantation (BTT) and now prioritized Status 2 under the current allocation policy. This study evaluated waitlist post-transplant outcomes of patients supported with 5.0/5.5 devices. Methods The United Network Organ Sharing registry was used identify adults waitlisted or transplanted 5.0 5.5 from 2010 2021. Separate analyses were performed for by Competing analysis included rates transplantation, recovery, death...
Healthcare providers currently calculate risk of the composite outcome morbidity or mortality associated with a coronary artery bypass grafting (CABG) surgery through manual input variables into logistic regression-based calculator. This study indicates that automated artificial intelligence (AI)-based techniques can instead risk. Specifically, we present novel numerical embedding enable NLP (natural language processing) models to achieve higher performance than calculator using single...
Abstract OBJECTIVES The gold standard metric for centre-level performance in orthotopic heart transplantation (OHT) is 1-year post-OHT survival. However, it unclear whether centre at 1 year predictive of longer-term outcomes. This study evaluated factors impacting OHT. METHODS Patients who underwent OHT the USA between 2010 and 2021 were identified using United Network Organ Sharing data registry. primary outcome was 5-year survival conditional on following Multivariable Cox proportional...
Objectives. The upper limit of recipient age for combined heart-kidney transplantation (HKT) remains controversial. This study evaluated the outcomes HKT in patients aged ≥65 years. Methods. United Network Organ Sharing (UNOS) was used to identify undergoing from 2005 2021. Patients were stratified by at transplantation: <65 and ≥ 65 primary outcome one-year mortality. Secondary included 90-day 5-year mortality, postoperative new-onset dialysis, stroke, acute rejection prior discharge,...
Heart-lung transplantation (HLTx) is relatively uncommon, and there a paucity of literature to suggest an age at which older recipients may be exposed excess risk for mortality. This analysis aimed identify threshold that predicts adverse outcomes after HLTx.The United Network Organ Sharing registry was used adult patients undergoing HLTx from 2005 2021. The primary outcome 1-year Threshold regression the impacts Kaplan-Meier model survival, Cox proportional hazards modeling...
Objectives. Heart transplantation (HT) is a definitive therapy for refractory heart failure, making it the gold-standard treatment recipients with end-stage disease. allocation policy (HAP) in United States was changed on October 18th, 2018. The aim of this study to assess effect new racial disparities outcomes. Methods. Network Organ Sharing (UNOS) registry used identify adult undergoing isolated HT between 2010 and 2021. Recipients were stratified into pre-HAP (January September 2018) vs....