- Ethics and bioethics in healthcare
- Tryptophan and brain disorders
- Stress Responses and Cortisol
- Cardiac Health and Mental Health
- Stress and Burnout Research
- Mental Health Research Topics
- Menopause: Health Impacts and Treatments
- Mental Health Treatment and Access
- Schizophrenia research and treatment
- Child and Adolescent Psychosocial and Emotional Development
- Bipolar Disorder and Treatment
- Ethics in medical practice
- Anesthesia and Neurotoxicity Research
- Diabetes Treatment and Management
- Cardiovascular Function and Risk Factors
- Human Health and Disease
- Treatment of Major Depression
- Cerebrovascular and Carotid Artery Diseases
- Heart Rate Variability and Autonomic Control
- Family Caregiving in Mental Illness
- Electroconvulsive Therapy Studies
- Neurological Disorders and Treatments
- Psychological Treatments and Disorders
- Nursing care and research
- Health and Medical Education
University of Chile
2009-2023
Hospital Clínico de la Universidad de Chile
2011-2022
London School of Hygiene & Tropical Medicine
2010
The treatment gap for people with mental disorders exceeds 50% in all countries of the world, approaching astonishingly high rates 90% least resourced countries, even serious associated significant role impairments 1,2,3. A number recent initiatives have called action to scale up services based on evidence effective interventions and respect human rights 4,5. Evidence treatments has been synthesized forthcoming Mental Health Gap Action Programme (mhGAP) guidelines World Organization (WHO)...
Major depressive disorder (MDD) is a prevalent condition which has well-known association with ischemic cardiomyopathy, probably explained by an inflammatory mediator mechanism. Statins, besides reducing cholesterol production, have pleiotropic effects including anti-inflammatory activity. The goal was to evaluate the effect of statins as addition standard therapy on mood status, brain perfusion, and neurocognitive performance in MDD.We studied 20 MDD patients single-photon emission...
<b><i>Background:</i></b> Major depressive disorder (MDD) is an important independent risk factor for cardiovascular disease. Cumulative data suggest that patients exhibit derangement in regional cerebral blood flow (rCBF), although underlying mechanisms remain mostly unknown. Endothelial dysfunction (ED), defined as different forms of abnormal endothelial activity, plays a key role the pathogenesis vascular ED associated with several clinical conditions characterized...
The practices and systems of mental health in Latin America the Caribbean are heterogeneous connected to dissociation between national macro complex quotidian that occurs daily attention pathologies. care experiences diverse go back 1960s; these took a boost with Caracas Declaration 1990. Health Care Reform has had several stages, lately focused strength derives from growing psychiatric epidemiology "base". In addition, it notes majority countries have National Plan Mental Health, but they...
In ethical terms the profile that doctor's rôle has acquired in today's society not been sufficiently considered as an analysis' object neither among medical corps nor other reflection instances, even though effects of this insensible but significant change can be noticed multiple aspects professional practice.To begin with, "legalization" activity, path from a doctor-patient relationship to another one type doctor-client, pressure administrated medicine puts on temporality act, etc.,...
Medwave es una revista electrónica revisada por pares y de acceso gratuito, que contiene artículos originales revisión sobre determinantes clínicos, sociales, políticos económicos en salud, investigación el ámbito clínico biomédico. is an online-only, peer-reviewed and open Access biomedical general journal with original review articles con clinical, social, political economic determinants of health, research on clinical aspects.
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Objetivos: La relación entre diversas variaciones de la ingesta alimentaria y los trastornos del ánimo es un fenómeno bien conocido para diversos clÃnicos. No obstante estos fenómenos han sido escasamente estudiados a fecha. Los métodos evaluación atracón o âcravingâ son diversos, lo que ha generado hallazgos heterogéneos superficiales. El objetivo esta revisión análisis fenomenologÃa craving las relaciones nutrición ánimo, especÃficamente con el trastorno bipolar (TBP).
Medwave es una revista electrónica revisada por pares y de acceso gratuito, que contiene artículos originales revisión sobre determinantes clínicos, sociales, políticos económicos en salud, investigación el ámbito clínico biomédico. is an online-only, peer-reviewed and open Access biomedical general journal with original review articles con clinical, social, political economic determinants of health, research on clinical aspects.
Statins are widely used as an effective therapy for ischemic vascular disorders and employed primary secondary prevention in cardiac cerebrovascular diseases. Their hemostatic mechanism has also been shown to induce changes cerebral blood flow that may result neurocognitive improvement subjects with Major Depressive Disorder. Behavioral data, various tests, resting-state brain perfusion data were obtained at the start of this study three months post-therapy from a small cohort participants...