A5082193061- Cervical Cancer and HPV Research
- Global Cancer Incidence and Screening
- Adolescent Sexual and Reproductive Health
- HIV/AIDS Research and Interventions
- Colorectal Cancer Screening and Detection
- Hepatitis B Virus Studies
- Genital Health and Disease
- Reproductive Health and Contraception
- BRCA gene mutations in cancer
- Cancer Risks and Factors
- Reproductive tract infections research
- Global Maternal and Child Health
- Advances in Oncology and Radiotherapy
- Vaccine Coverage and Hesitancy
- Child and Adolescent Health
- Family Support in Illness
- Reproductive Biology and Fertility
- Ovarian function and disorders
- Healthcare Policy and Management
- Childhood Cancer Survivors' Quality of Life
- Mobile Health and mHealth Applications
- Primary Care and Health Outcomes
- Health Literacy and Information Accessibility
- Cardiac, Anesthesia and Surgical Outcomes
- Reproductive Health and Technologies
University of Cape Town
2016-2025
South African Medical Research Council
2016-2024
University of KwaZulu-Natal
2002-2024
Groote Schuur Hospital
2020-2022
Women's Health Research Institute
2019-2022
Western Cape Department of Health
2018-2022
Family Research Institute
2021
ORCID
2021
South African Tuberculosis Vaccine Initiative
2018-2020
South African Radio Astronomy Observatory
2019
The aim of this study was to explore and understand women's pathways breast cancer diagnosis factors influencing journey.Indepth interviews were conducted with clients at a tertiary level clinic in Cape Town, South Africa. A thematic analysis performed underpinned by the theoretical concepts Model Pathways Treatment framework.20 women interviewed within 1 week being diagnosed cancer.The average time between discovery bodily changes 8.5 months. Deficits self-awareness knowledge symptoms...
Cervical cancer and infection with human immunodeficiency virus (HIV) are both major public health problems in South Africa. The aim of this study was to determine the risk cervical pre-cancer among HIV positive women Data were derived from a case-control that examined association between hormonal contraceptives invasive cancer. conducted Western Cape (South Africa), January 1998 December 2001. There 486 cancer, 103 control atypical squamous cells undetermined significance (ASCUS), 53...
The advent of democracy in South Africa 1994 created a unique opportunity for new laws and policies to be passed. Today, decade later, African reproductive health the that underwrite them are among most progressive comprehensive world terms recognition they give human rights, including sexual rights. This paper documents changes policy services have occurred, focusing particularly on key areas health: contraception, maternal health, termination pregnancy, cervical breast cancer, gender-based...
This study examined the concordance of genital human papillomavirus (HPV) infection in 254 heterosexually active couples and impact HIV coinfection. Genital HPV detection was significantly more common among HIV-infected women than HIV-seronegative (99 [68%] 145 vs. 33 [31%] 107 women; P < .001); similarly, men (67 [72%] 93 65 [43%] 150 men, respectively; .001). male partners had a greater prevalence did (38 [58%] 27 [32%] 85 men; = .001), indicating that coinfection one partner has...
The prevention of unintended pregnancies among HIV positive women is a neglected strategy in the fight against HIV/AIDS. Women who want to avoid can do this by using modern contraceptive method. Contraceptive choice, particular use long acting and permanent methods (LAPMs), poorly understood HIV-positive women. This study aimed compare factors that influence women's choice contraception knowledge attitudes towards IUD female sterilization HIV-status high prevalence setting, Cape Town, South...
Abstract Background Human papillomavirus (HPV) is the aetiological agent for cervical cancer and genital warts. Concurrent HPV HIV infection in South African population high. positive (+) women are often infected with multiple, rare undetermined types. Data on incidence genotype distribution based commercial detection kits, but these kits may not detect all types + women. The objectives of this study were to (i) identify detected by genotyping present a specimen from an woman using next...
HPV-based screen and treat is the recommended approach for cervical cancer screening in low-resource settings, but quite low specificity of human papillomavirus (HPV) testing, particularly women living with HIV, leads to overtreatment. We evaluated whether HPV type restriction more stringent cutoffs on Xpert optimise performance characteristics this assay treat.We recruited HIV-negative HIV-positive aged 30-65 years from a primary care facility referral colposcopy clinic Cape Town, South...
Cancer screening programs hold much potential for reducing the cervical cancer disease burden in developing countries. The aim of this study was to determine feasibility mobile health (mHealth) phone technology improve management and follow-up clients with precursor lesions. A sequential mixed methods design employed study. Quantitative data collected using a cross-sectional survey 364 women eligible Pap smear at public sector services Cape Town, South Africa. Information on...
Diagnosing cancer earlier can enable timely treatment and optimize outcomes. Worldwide, national control plans increasingly encompass early diagnosis programs for symptomatic patients, commonly comprising awareness campaigns to encourage prompt help-seeking possible symptoms health system policies support diagnostic assessment access treatment. By their nature, involve complex public interventions aiming address unmet needs by acting on patient, clinical, factors. However, there is...
Abstract Objectives To explore healthcare workers (HCW) experiences, barriers and facilitators in managing patients with symptoms of possible breast, cervical or colorectal cancer. Design A qualitative in-depth interview study HCWs cancer symptoms. We also conducted workshops a group to check the credibility findings. Setting The was staff working primary, secondary tertiary health facilities Eastern Western Cape South Africa (SA) Harare Bulawayo their referral provinces Zimbabwe....
The value of screening for cervical cancer has been proven. Such in developed countries achieved a decrease incidence and mortality by about 80%. Although facilities are available certain parts developing countries, the remains very high many patients present with late stage disease. study was performed among women from different socioeconomic circumstances (low, middle, upper social/financial backgrounds). assessment means questionnaire. majority lower socio-economic multiple risk factors...
Abstract Qualitative research was conducted with HIV-positive women and men of reproductive age attending HIV/AIDS care treatment services at a public health clinic in Cape Town, South Africa. Focus group discussions were held (n = 4) 4), in-depth interviews four to explore perceptions experiences sexual (SRH) care. Respondents praised their treatment, reflected on how it improved quality life contrasted this suboptimal other facilities, including SRH services. Women wanted integrated...
Cervical cancer and infection with human immunodeficiency virus (HIV) are both important public health problems in South Africa (SA). The aim of this study was to determine the prevalence cervical squamous intraepithelial lesions (SILs), high-risk papillomavirus (HR-HPV), HPV viral load genotypes HIV positive women initiating anti-retroviral (ARV) therapy. A cross-sectional survey conducted at an treatment clinic Cape Town, SA 2007. specimens were taken for cytological analysis testing....
Objective The aim of this study was to explore and understand women's experience with cervical cancer screening the referral pathways for abnormal Papanicolau (Pap) smears. Design setting Focus group discussions were conducted first time colposcopy clinic attendees at a tertiary hospital in Cape Town, South Africa during November 2014. A thematic analysis identify key themes. Initial coding categories drawn from interview guide. Participants 27 women participated 4 focus discussions. Results...