Hee‐Young Kim

ORCID: 0000-0002-9400-3098
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About
Contact & Profiles
Research Areas
  • Ear Surgery and Otitis Media
  • Vestibular and auditory disorders
  • Food Quality and Safety Studies
  • Voice and Speech Disorders
  • Hepatitis C virus research
  • Obstructive Sleep Apnea Research
  • Dysphagia Assessment and Management
  • Health and Wellbeing Research
  • Ear and Head Tumors
  • Diverse Approaches in Healthcare and Education Studies
  • Gastroesophageal reflux and treatments
  • Cerebral Palsy and Movement Disorders
  • Stroke Rehabilitation and Recovery
  • Hepatitis B Virus Studies
  • Bone health and osteoporosis research
  • Respiratory and Cough-Related Research
  • Nutrition and Health in Aging
  • Psychosocial Factors Impacting Youth
  • Healthcare and Venom Research
  • HIV Research and Treatment
  • Pharmacological Effects of Natural Compounds
  • Subtitles and Audiovisual Media
  • Cultural and Historical Studies
  • Nutrition, Health and Food Behavior
  • Family and Disability Support Research

Kyung Hee University
2024

Kim's Eye Hospital
2014-2023

Samsung (South Korea)
2023

Harvard University
2023

Boston University
2023

Seoul Medical Center
2023

Chonnam National University Hospital
2020

Institut Pasteur Korea
2013-2017

Pusan National University
2013-2016

University of Ulsan
2012

Alternatenobaric vertigo (ABV) develops when the middle ear pressure (MEP) is not equal at same height in sea or air. This possible altitude changes. Eustachian tube dysfunction (ETD) a common cause of ABV. In this case report, we discuss patient who experienced repeated bouts ground-level alternobaric (GLABV) due to ETD. We also how Conversational Generative Pre-trained Transformer (ChatGPT) might be used creation report. A 41-year-old male complained ground level on several occasions. His...

10.7759/cureus.36830 article EN Cureus 2023-03-28

The purpose of this study was to analyze patients with epiglottic collapse, especially their clinical characteristics related obstructive sleep apnea and phenotype labeling using drug-induced endoscopy.An age-sex matched case-control conducted compare the collapse (Epi group) without (non-Epi group). All underwent endoscopy January, 2015, March, 2019, in a tertiary hospital for suspected symptoms. Demographic factors, underlying disease, overnight polysomnography, were analyzed.There no...

10.5664/jcsm.8904 article EN Journal of Clinical Sleep Medicine 2020-10-23

Patients who suffer from Eustachian tube dysfunction (ETD) experience a significant decline in quality of life. To enhance patient outcomes, it is crucial to establish an accurate diagnosis, assess treatment effectiveness, and evaluate the severity condition. Substantial progress has recently been made identifying biomarkers (BMs) developing ETD clinical outcome assessments (COAs). This study examines current state BMs COAs ETD, including methods evaluated historically their potential...

10.21801/ppcrj.2024.101.3 article EN Principles and Practice of Clinical Research Journal 2024-04-12

Despite recent advances in curing chronic hepatitis C (CHC), the high economic burden to therapy, viral drug resistance, difficult treat virus (HCV) genotypes and patient groups are still of concern. To address this unmet medical needs, we devised strategies identify novel interventions through target-free high-throughput screening small molecules utilizing a phenotypic-based HCV infection assay. Thereby, very potent (EC50 46 ± 26 pM) iminodipyridinopyrimidine (IDPP) candidate was selected,...

10.1038/srep44676 article EN cc-by Scientific Reports 2017-03-23

Hepatitis C virus (HCV) infection is a global health concern with chronic liver damage threatening 3% of the world's population. To date, standard care combination pegylated interferon-alpha ribavirin, and recently two direct acting antivirals have entered clinics. However, because side effects, drug resistance viral genotype-specific differences in efficacy current potentially also future therapies their limitations. Here, we describe development phenotypic high-throughput assay to identify...

10.1016/j.antiviral.2013.04.020 article EN cc-by-nc-nd Antiviral Research 2013-05-06

This editorial explores the notion of "within normal limits" (WNL) in tympanometry, focusing on its limitations identifying conditions such as alternobaric vertigo (AV) and ground-level (GLAV). Tympanometry is a simple diagnostic instrument that measures middle ear (ME) pressure, compliance, canal volume, width tympanogram. While WNL ranges are based average values from population, they often do not account for individual differences, leading to possible misdiagnoses. Conditions AV, caused...

10.15406/joentr.2024.16.00546 article EN Journal of Otolaryngology-ENT Research 2024-07-02

To investigate the contributions of carboxyl-terminal nucleic acid binding domain HBV core (C) protein for hepatitis B virus (HBV) replication, chimeric C proteins were generated by substituting varying lengths carboxyl-terminus duck (DHBV) corresponding regions protein. All formed particles. A with 221–262 amino acids DHBV protein, in place 146–185 supported pregenomic RNA (pgRNA) encapsidation and DNA synthesis: 40% sequence identity or 45% homology nucleic-acid was sufficient pgRNA...

10.1371/journal.pone.0041087 article EN cc-by PLoS ONE 2012-07-20

My own experience in the medical treatment of a lot patients for 20 years has proved that many cases have both Laryngopharyngeal reflux (LPR) and Eustachian tube obstruction (ETO) at same time.In these cases, ETO can be cause LPR, or, conversely, LPR ETO, hence it is natural concept 'reciprocal causal relationship between ETO' emerges from it.A combination like 'hearing loss' or/and 'ear fullness' 'dizziness (vertigo) 'tinnitus' 'headache (migraine)' due to regarded as consisting major...

10.15406/joentr.2015.02.00046 article EN cc-by-nc Journal of Otolaryngology-ENT Research 2015-06-15

본 연구는 뇌졸중 후 상지기능의 관련 요인과 각 요인의 상대적 영향력을 알아보기 위해 시행되었다. MMSE-K(Mini Mental State Examination Korean version) 24점 이상인 100명의 환자를 대상으로 하였다. 상지기능은 성별, 우세손, 뇌손상 원인, 뇌반구 손상부위, 신체마비 부위, 언어장애 유무와는 유의한 차이가 없었으나(p>0.05), 아탈구 유무는 상지기능에 차이를 보였다(p<0.05). 상지근력(Manual Muscle Testing), 고유수용성감각(Proprioception), 근 긴장도 (Modified Ashworth Scale), 장악력(Grip strength), 통증(Visual Analog Scale)과 상관관계를 위의 변수를 모두 포함하여 분석하면 77.6%의 상지기능 설명력을 보였고 이 중 상지근력이 가장 높은 보였다. 환자의 재활을 위해서는 특히 상지근력 강화와 더불어 고유수용성감각, 긴장도, 장악력, 통증 그리고...

10.5392/jkca.2009.9.7.202 article EN The Journal of the Korea Contents Association 2009-07-28

The aim of this paper is to present the thesis that necessity Eustachian tube catheterization can be rationalized irrespective time, through a text summary knowledges and discoveries by senior doctors for long time.Focusing on concept development related from 1724 1861, its process subdivided into seven sub-themes: 1) Beginning therapeutic reasons.2) Evaluation patency tube.3) Normal state as prerequisite normal hearing.4) Therapeutic test inflation tube.5) diagnostic reasons.6) first step...

10.15406/joentr.2016.04.00084 article EN cc-by-nc Journal of Otolaryngology-ENT Research 2016-01-19

ustachian tube dysfunction (ETD) can lead to a loss of vestibular function and eventually give rise peripheral [1].

10.24983/scitemed.aohns.2017.00017 article EN cc-by 2017-01-01

Decades of research have been devoted to understanding the complicated connections between ears, nose, throat, and stomach. Pioneers in discipline otolaryngology/ear, throat (ENT), James Yearsley (1805–1869) Peter Allen (1826–1844), produced theories concepts that allowed us determine relationship these items. The current study has contributed clarifying complex Eustachian tube dysfunction (ETD), alternobaric vertigo (ABV), gastroesophageal reflux disease (GERD), laryngopharyngeal (LPR),...

10.15406/joentr.2023.15.00521 article EN cc-by-nc Journal of Otolaryngology-ENT Research 2023-02-22

Background: Mild cognitive impairment (MCI) is considered as a transitional state between normal aging and dementia can be subdivided into amnestic vs. nonamnestic single multiple domains types. It suggested that these clinical subtypes may have different underlying etiologies outcomes. The MCI differs in the performance profile on memory testing: retention retrieval deficit. Generally, deficit attributed to medial temporal dysfunction frontal dysfunction. We tried determine whether there...

10.12779/dnd.2012.11.1.18 article EN Dementia and Neurocognitive Disorders 2012-01-01

Generally, most people who experience problems report such things as 'hearing loss' or/ and 'ear fullness' or/and 'dizziness (vertigo) 'tinnitus' 'headache (migraine)'.In all cases, some process should be performed to rule out possible mechanical causes for above mentioned symptoms middle ear effusion Eustachian tube obstruction before all.Ideally normal cavity pressure with balance between both ears.This is the essential prerequisite tests of vestibular function, tinnitus, headache,...

10.15406/joentr.2014.01.00001 article EN cc-by-nc Journal of Otolaryngology-ENT Research 2014-11-19

Submit Manuscript | http://medcraveonline.com J Otolaryngol ENT Res 2015, 3(2): 00057 The middle ear is very much like a specialized paranasal sinus, called the tympanic cavity; it, sinuses, hollow mucosa-lined cavity in skull that ventilated through nose [5]. Tympanic and mastoid are named on basis of anatomy. However, if we view things from different angle, can regard them as one ‘paranasal sinuses’, ‘tympanic sinus’ maxillary or frontal ethmoid sphenoid sinus physiology function [1]. This...

10.15406/joentr.2015.03.00057 article EN cc-by-nc Journal of Otolaryngology-ENT Research 2015-09-02

Letter to the Editor in reference to: "Eustachian tube dysfunction: Consensus statement on definition, types, clinical presentation and diagnosis"Dear Editor,After reading editorial comment article entitled, diagnosis" published Clinical Otolaryngology (2015;40 (5): 407–411), I would like congratulate authors for their successful consensus, wish make some contributions discussion.In article, alternobaric vertigo (ABV) was left off consensus statement, even though baro-challenge-induced...

10.22541/au.170665730.07580554/v1 preprint EN Authorea (Authorea) 2024-01-30

Although there is an established link between Magnolia Cortex (MO) and lipid metabolism in previous research, its exploration within the context of obesity has been limited. Therefore, present study investigated therapeutic effects MO on mechanism action vitro vivo. Our chromatography analysis revealed that Honokiol Magnolol are contained extract. In experiments showed droplets, adipogenic, lipogenic genes were notably diminished by increasing sirtuin 1 (SIRT1) AMP-activated kinase (AMPK)...

10.1016/j.heliyon.2024.e27600 article EN cc-by-nc-nd Heliyon 2024-03-01

Introduction: Chronic obstructive pulmonary disease (COPD) is one of the leading causes death worldwide and has a prevalence 11.7%. Current treatment focuses on reducing symptoms exacerbations, as no definitive intervention exists. Regenerative treatments such mesenchymal stem cell (MSCs) therapy have shown promise in preclinical clinical studies. This article presents study protocol to evaluate efficacy adipose-derived (AD) MSCs improving FEV-1 COPD patients. Methods: A phase III,...

10.21801/ppcrj.2024.101.1 article EN Principles and Practice of Clinical Research Journal 2024-04-12
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