- Genetic and phenotypic traits in livestock
- Genetic Mapping and Diversity in Plants and Animals
- Animal Nutrition and Physiology
- Meat and Animal Product Quality
- Food Quality and Safety Studies
- Livestock and Poultry Management
- Agriculture, Soil, Plant Science
- Fish Biology and Ecology Studies
- Healthcare and Venom Research
- Animal Behavior and Welfare Studies
- Genetic Associations and Epidemiology
- Aquaculture disease management and microbiota
- Metabolism, Diabetes, and Cancer
- Genetics and Plant Breeding
- Aquaculture Nutrition and Growth
- Muscle Physiology and Disorders
- Adipose Tissue and Metabolism
- Cancer-related molecular mechanisms research
- Nutrition, Health and Food Behavior
- Biochemical Analysis and Sensing Techniques
- RNA and protein synthesis mechanisms
- Effects of Environmental Stressors on Livestock
- Ziziphus Jujuba Studies and Applications
- Ginseng Biological Effects and Applications
- Biochemical effects in animals
Kongju National University
2019-2024
National Institute of Animal Science
2014-2023
Rural Development Administration
2016-2018
Chungnam National University
2013-2016
Gyeongsang National University
2011-2015
Seoul National University
1993-2015
Lund University
2006-2011
Uppsala University
2005-2006
Northwestern University
1968
University of Illinois Chicago
1963-1968
Certain of the data accumulated over course more than 4 years in a prospective study coronary heart disease being carried on an industrial population have been presented. In base 1,989 men, 88 cases developed: angina pectoris, 47 men; myocardial infarction, 28 death from coronary, disease, 13 men. This approximates one case per 100 men year. The development clinical has shown association with early age father, history "noncardiac" chest discomfort, chronic cough, shortness breath, peptic...
The aim of this study was to examine the effect chicken line on contents endogenous compounds, including carnosine, anserine, creatine, and inosine 5′-monophosphate (IMP), in breast thigh meats from 5 lines Korean native for development high-quality meat breeds. Additionally, effects sex (male or female) type (breast meat) were examined. In total, 595 F1 progeny [black: 90 (male: 45, female: 45); gray-brown: 110 52, 58); red-brown: 136 68, 68); white: 126 63, 63); yellow-brown: 133 62, 71)]...
Muscle development and lipid accumulation in muscle critically affect meat quality of livestock. However, the genetic factors underlying myofiber-type specification intramuscular fat (IMF) remain to be elucidated. Using two independent intercrosses between Western commercial breeds Korean native pigs (KNPs) a joint linkage-linkage disequilibrium analysis, we identified 488.1-kb region on porcine chromosome 12 that affects both reddish color (a*) IMF. In this critical region, only MYH3 gene,...
The high- and low-growth lines of chickens have been developed from a single founder population by divergent selection for body weight at 56 days age more than 40 generations. two show ninefold difference in several interesting correlated responses such as altered composition metabolic differences. We generated reciprocal intercross comprising >800 F 2 birds. In previous study, we reported the detection 13 quantitative trait loci (QTLs) affecting growth. Here report QTLs (fat deposition,...
Two growth-selected lines in chickens have been developed from a single founder population by divergent selection for body weight at 56 days of age. After more than 40 generations they show nine-fold difference age and large differences growth rate, appetite, fat deposition metabolic characteristics. We generated intercross between these comprising 800 F2 birds. QTL mapping revealed 13 loci affecting growth. The most striking observation was that the allele high line all cases associated...
Objective This study estimated the genetic parameters for body weight gain and growth curve parameter traits in Korean native chicken (KNC). Methods A total of 585 F1 chickens were used along with 88 their F0 birds. Body weights measured every 2 weeks from hatching to 20 age measure at 2-week intervals. For each individual, a logistic model was fitted longitudinal dataset obtain three (α, asymptotic final weight; β, inflection point; γ, constant scale that proportional overall rate). Genetic...
Abstract Niddm1i, a 16-Mb locus within the major diabetes QTL in diabetic GK rat, causes impaired glucose tolerance congenic NIDDM1I strain. Niddm1i is homologous to both human and mouse regions linked with type 2 susceptibility. We employed multiple analyses of F2 progeny selected for one recombination event combined characterization subcongenic strains. Fine mapping located hyperglycemia 700 kb (Niddm1i4, P = 5 × 10−6). Two adjacent loci were also detected, allele at Niddm1i2 (500 kb)...
This study was aimed at comparing the taste-related compound content in breast and leg meat from 100-d-old Korean native chickens (KNC-100) 32-d-old commercial broilers (CB-32) determining changes these compounds during cooking. Cocks certified meat-type broiler (Ross) chicken (Woorimatdag) strains were raised under similar standard conditions, a total of 10 birds each breed slaughtered 32 100 d age, which represents their market ages, respectively. Raw cooked samples prepared separately...
We conducted a genome-wide linkage analysis to identify quantitative trait loci (QTL) that influence meat quality-related traits in large F2 intercross between Landrace and Korean native pigs. Thirteen of the m. longissimus lumborum et thoracis were measured more than 830 progeny. All these animals genotyped with 173 microsatellite markers located throughout pig genome, GridQTL program based on least squares regression model was used perform QTL analysis. identified 23 significant eight...
Myosin heavy chain (MyHC) isoforms consist of Myh7, Myh2, Myh1, and Myh4, which are expressed in skeletal muscle tissues during postnatal development. These genes influence the contraction–relaxation activity muscles involved determining composition such as proportion fast-to-slow and/or slow-to-fast fiber types. Among them, Myh1 is associated with contraction both transition. However, transition mechanism not well understood. For this study, we first produced porcine transgenic (TG) mice to...
This study investigated the proximate composition and l-carnitine betaine content of meats from 5 lines Korean indigenous chicken (KIC) for developing highly nutritious meat breeds with health benefits bioactive compounds such as in meat. In addition, relevance gender (male female) type (breast thigh meat) was examined. A total 595 F1 progeny (black [B], grey-brown [G], red-brown [R], white [W], yellow-brown [Y]) 70 full-sib families were used. The moisture, protein, fat, ash contents...
Abstract In livestock social interactions, genetic effects (SGE) represent associations between phenotype of one individual and genotype another. Such occur when the trait interest is affected by transmissible phenotypes partners. The aim this study was to estimate SGE direct (DGE, an on its own phenotype) average daily gain (ADG) in Landrace pigs, conduct single-step genome-wide association using DGE as dependent variables identify quantitative loci (QTLs) their positional candidate genes....
Meningocele and meningoencephalocele of the skull are congenital deformities. Various species, such as pigs, dogs, cats, susceptible to meningocele incidence is higher in large white landrace pigs. In this study, swelling was observed fontanel areas median planes cap two female piglets same litter. Gross clinical examination, neurological computed tomography (CT), magnetic resonance imaging (MRI) were conducted on symptomatic piglets. The gross examinations revealed no specific findings,...
재래닭고기는 broiler 닭고기와 비교하여 단백질 함량은 높고, 지방 낮을 뿐만 아니라, 독특한 풍미 및 조직 감으로 인해 고품질 식육자원으로 여겨지고 있다. 게다가 최근 고유 유전자원 확보 유전자원의 다양성이 요구되고 있고, 식육에 대한 소비자의 요구가 증가함에 따라 재래닭을 이용한 새로운 고급 육질형 종계의 생산이 시도되고 따라서 본 연구는 깃털색에 흑색, 회갈색, 적갈색, 백색 황갈색으로 분류되어 있는 한국 재래닭 5계통 닭고기의 품질 특성을 측정 종계 생산을 위한 선발 개량 육종 계획에 필요한 정보를 제공하고자 수행되었다. 연구 수행을 위해 5계통의 총 595 <TEX>$F_1$</TEX> 개체를 20주령에 도계하였으며, 닭고기 특성으로써 가슴육과 다리육의 도계 후 15분 pH, 최종 보수력 육색을 측정하여 간 차이를 비교하였고, 성별에 따른 차이 또한 비교하였다. 연구의 결과, pH는 계통 성별 간에 유의적인 차이가 것으로 나타났다(P<0.05). 하지만 pH...
Pork belly is a cut of meat with high worldwide demand. However, although the comprised multiple muscles and fat, unlike loin muscle, research on their genetic parameters has yet to focus representative cut. To use swine breeding, it necessary estimate heritability against pork traits. Moreover, estimating correlations needed identify relationship among traditional carcass quality This study sought carcass, belly, component traits, as well them, confirm whether these traits can be improved.A...
The proper function of mammalian mitochondria necessitates a coordinated expression both nuclear and mitochondrial genes, most likely due to the co-evolution genomes. non-protein coding regions DNA (mtDNA) including D-loop, tRNA rRNA genes form major component this regulated unit. Here we present comparative analyses non-protein-coding from 27 Rattus norvegicus mtDNA sequences. There were two variable positions in 12S rRNA, 20 16S eight within 13 D-loop. Only one three neutrality tests used...
Clinical-chemical traits are essential when examining the health status of individuals. The aim this study was to identify quantitative trait loci (QTL) and associated positional candidate genes affecting clinical-chemical in a reciprocal F(2) intercross between Landrace Korean native pigs. Following an overnight fast, 25 serum phenotypes related (e.g., hepatic function parameters, renal electrolyte, lipids) were measured >970 progeny. All experimental samples subjected genotyping analysis...
Muscle satellite cells (MSCs) represent a devoted stem cell population that is responsible for postnatal muscle growth and skeletal regeneration. An important characteristic of MSCs they encompass multi potential mesenchymal activity are able to differentiate into myocytes adipocytes. To achieve global view the genes differentially expressed in MSCs, myotube formed-cells (MFCs) adipocyte-like (ALCs), we performed large-scale EST sequencing normalized cDNA libraries developed from bovine...
Fatty acid composition is one of the most important meat quality traits because it can contribute to functional, sensorial, and nutritional factors. In this study, quantitative trait locus (QTL) analyses for fatty were investigated in thigh breast Korean native chicken (KNC).In total, 18 from each sample using 83 parents, 595 F1 chicks 20 week old. Genotype assessment was performed 171 informative DNA markers on 26 autosomes. The KNC linkage map constructed by CRI-MAP software, which...